Yr Athro Rhiannon Owen

Uchafbwyntiau Ymchwil

1. Lyons, J., Akbari, A., Abrams, K., Lorenzo, A., Dhafari, T., Chess, J., Denaxas, S., Fry, R., Gale, C., Gallacher, J., Griffiths, L., Guthrie, B., Hall, M., Jalali-najafabadi, F., John, A., MacRae, C., McCowan, C., Peek, N., O’Reilly, D...., & Owen, R. (2023). Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005–2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals. The Lancet Regional Health - Europe, 32, 100687

   https://doi.org/10.1016/j.lanepe.2023.100687, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63905

   http://dx.doi.org/10.1016/j.lanepe.2023.100687
2. Owen, R., Lyons, J., Akbari, A., Guthrie, B., Agrawal, U., Alexander, D., Azcoaga-Lorenzo, A., Brookes, A., Denaxas, S., Dezateux, C., Fagbamigbe, A., Harper, G., Kirk, P., Özyiğit, E., Richardson, S., Staniszewska, S., McCowan, C., Lyons, R., & Abrams, K. (2023). Effect on life expectancy of temporal sequence in a multimorbidity cluster of psychosis, diabetes, and congestive heart failure among 1·7 million individuals in Wales with 20-year follow-up: a retrospective cohort study using linked data. The Lancet Public Health, 8(7), e535-e545.

   https://doi.org/10.1016/s2468-2667(23)00098-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63756

   http://dx.doi.org/10.1016/s2468-2667(23)00098-1
3. Fagbamigbe, A., Agrawal, U., Azcoaga-Lorenzo, A., MacKerron, B., Özyiğit, E., Alexander, D., Akbari, A., Owen, R., Lyons, J., Lyons, R., Denaxas, S., Kirk, P., Miller, A., Harper, G., Dezateux, C., Brookes, A., Richardson, S., Nirantharakumar, K., Guthrie, B...., & McCowan, C. (2023). Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland. PLOS ONE, 18(11), e0294666

   https://doi.org/10.1371/journal.pone.0294666, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65255
4. Tsang, R., Agrawal, U., Joy, M., Byford, R., Robertson, C., Anand, S., Hinton, W., Mayor, N., Kar, D., Williams, J., Victor, W., Akbari, A., Bradley, D., Murphy, S., O’Reilly, D., Owen, R., Chuter, A., Beggs, J., Howsam, G...., & Lusignan, S. (2023). Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study. Journal of the Royal Society of Medicine

   https://doi.org/10.1177/01410768231205430, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65099

   http://dx.doi.org/10.1177/01410768231205430
5. Umemneku-Chikere, C., Wheaton, L., Poad, H., Ray, D., Andrade, I., Khan, S., Tappenden, P., Abrams, K., Owen, R., & Bujkiewicz, S. (2023). Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis. Journal of Clinical Epidemiology, 164, 96-103.

   https://doi.org/10.1016/j.jclinepi.2023.10.018, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65015

   http://dx.doi.org/10.1016/j.jclinepi.2023.10.018
6. Lowthian, E., Abbasizanjani, H., Bedston, S., Akbari, A., Cowley, L., Fry, R., Owen, R., Hollinghurst, J., Rudan, I., Beggs, J., Marchant, E., Torabi, F., Lusignan, S., Crick, T., Moore, G., Sheikh, A., & Lyons, R. (2023). Trends in SARS-CoV-2 infection and vaccination in school staff, students and their household members from 2020 to 2022 in Wales, UK: an electronic cohort study. Journal of the Royal Society of Medicine, 116(12), 413-424.

   https://doi.org/10.1177/01410768231181268, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63604

   http://dx.doi.org/10.1177/01410768231181268
7. Oppen, J., Owen, R., Jones, W., Beishon, L., & Coats, T. (n.d.) The effect of relative hypotension on 30-day mortality in older people receiving emergency care. Internal and Emergency Medicine

   https://doi.org/10.1007/s11739-023-03468-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64945

   http://dx.doi.org/10.1007/s11739-023-03468-5
8. Lowthian, E., Abbasizanjani, H., Bedston, S., Akbari, A., Cowley, L., Fry, R., Owen, R., Hollinghurst, J., Rudan, I., Beggs, J., Marchant, E., Torabi, F., Lusignan, S., Crick, T., Moore, G., Sheikh, A., & Lyons, R. (2023). Trends in SARS-CoV-2 infection and vaccination in school staff, students and their household members from 2020 to 2022 in Wales, UK: an electronic cohort study. Journal of the Royal Society of Medicine, 116(12), 413-424.

   https://doi.org/10.1177/01410768231181268, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64085

   http://dx.doi.org/10.1177/01410768231181268
9. Stannard, S., Berrington, A., Paranjothy, S., Owen, R., Fraser, S., Hoyle, R., Boniface, M., Wilkinson, B., Akbari, A., Batchelor, S., Jones, W., Ashworth, M., Welch, J., Mair, F., & Alwan, N. (2023). A conceptual framework for characterising lifecourse determinants of multiple long-term condition multimorbidity. Journal of Multimorbidity and Comorbidity, 13, 1-13.

   https://doi.org/10.1177/26335565231193951, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64502

   http://dx.doi.org/10.1177/26335565231193951
10. Fraser, S., Stannard, S., Holland, E., Boniface, M., Hoyle, R., Wilkinson, R., Akbari, A., Ashworth, M., Berrington, A., Chiovoloni, R., Enright, J., Francis, N., Giles, G., Gulliford, M., Macdonald, S., Mair, F., Owen, R., Paranjothy, S., Parsons, H...., & Alwan, N. (2023). Multidisciplinary ecosystem to study lifecourse determinants and prevention of early-onset burdensome multimorbidity (MELD-B) – protocol for a research collaboration. Journal of Multimorbidity and Comorbidity, 13

    https://doi.org/10.1177/26335565231204544, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64623

    http://dx.doi.org/10.1177/26335565231204544
11. Lowthian, E., Bedston, S., Kristensen, S., Akbari, A., Fry, R., Huxley, K., Johnson, R., Kim, H., Owen, R., Taylor, C., & Griffiths, L. (2023). Maternal Mental Health and Children’s Problem Behaviours: A Bi-directional Relationship?. Research on Child and Adolescent Psychopathology

    https://doi.org/10.1007/s10802-023-01086-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63770

    http://dx.doi.org/10.1007/s10802-023-01086-5
12. Tsang, R., Joy, M., Byford, R., Robertson, C., Anand, S., Hinton, W., Mayor, N., Kar, D., Williams, J., Victor, W., Akbari, A., Bradley, D., Murphy, S., O’Reilly, D., Owen, R., Chuter, A., Beggs, J., Howsam, G., Sheikh, A...., & Lusignan, S. (2023). Adverse events following first and second dose COVID-19 vaccination in England, October 2020 to September 2021: a national vaccine surveillance platform self-controlled case series study. Eurosurveillance, 28(3)

    https://doi.org/10.2807/1560-7917.es.2023.28.3.2200195, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62389
13. Bedston, S., Lowthian, E., Jarvis, C., Akbari, A., Beggs, J., Bradley, D., Lusignan, S., Griffiths, R., Herbert, L., Hobbs, R., Kerr, S., Lyons, J., Midgley, W., Owen, R., Quint, J., Tsang, R., Torabi, F., Sheikh, A., & Lyons, R. (2023). COVID-19 booster vaccination uptake and infection breakthrough amongst health care workers in Wales: A national prospective cohort study. Vaccine, 41(7), 1378-1389.

    https://doi.org/10.1016/j.vaccine.2023.01.023, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62336
14. Owen, R., Lyons, J., Akbari, A., Lyons, R., & Abrams, K. (2022). RWD115 Modelling the Effect of Multi-Indication Treatment in Patients With Multimorbidity Using Population-Scale Linked Electronic Health Records for Healthcare Policy and Decision-Making. Value in Health, 25(12), S471

    https://doi.org/10.1016/j.jval.2022.09.2340, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62208
15. Agrawal, U., Bedston, S., McCowan, C., Oke, J., Patterson, L., Robertson, C., Akbari, A., Azcoaga-Lorenzo, A., Bradley, D., Fagbamigbe, A., Grange, Z., Hall, E., Joy, M., Katikireddi, S., Kerr, S., Ritchie, L., Murphy, S., Owen, R., Rudan, I...., & Sheikh, A. (2022). Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales. The Lancet, 400(10360), 1305-1320.

    https://doi.org/10.1016/s0140-6736(22)01656-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61579
16. Torabi, F., Bedston, S., Lowthian, E., Akbari, A., Owen, R., Bradley, D., Agrawal, U., Collins, P., Fry, R., Griffiths, L., Beggs, J., Davies, G., Hollinghurst, J., Lyons, J., Abbasizanjani, H., Cottrell, S., Perry, M., Roberts, R., Azcoaga-Lorenzo, A...., & Lyons, R. (2022). Risk of thrombocytopenic, haemorrhagic and thromboembolic disorders following COVID-19 vaccination and positive test: a self-controlled case series analysis in Wales. Scientific Reports, 12(1)

    https://doi.org/10.1038/s41598-022-20118-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61394
17. Lowthian, E., Bedston, S., Akbari, A., Fry, R., Huxley, K., Johnson, R., Kristensen, S., Owen, R., Taylor, C., & Griffiths, L. (2022). Maternal mental health and children’s development: a bi-directional relationship?. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v7i3.1936, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61244
18. Owen, R., Lyons, J., Akbari, A., Davies, G., Griffiths, R., Torabi, F., & Lyons, R. (2022). Direct and indirect effects of the COVID-19 pandemic on mortality: an individual-level population-scale analysis.. International Journal of Population Data Science, 7(3)

    https://doi.org/10.23889/ijpds.v7i3.1922, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61241
19. Akbari, A., Bedston, S., Abbasizanjani, H., Davies, G., Fry, R., Lowthian, E., Lyons, J., Owen, R., Torabi, F., Khunti, K., & Lyons, R. (2022). Developing a population-scale harmonised ethnicity-spine in Wales.. In International Journal of Population Data ScienceSwansea University.

    https://doi.org/10.23889/ijpds.v7i3.1930, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61240
20. Delanerolle, G., Williams, R., Stipancic, A., Byford, R., Forbes, A., Tsang, R., Anand, S., Bradley, D., Murphy, S., Akbari, A., Bedston, S., Lyons, R., Owen, R., Torabi, F., Beggs, J., Chuter, A., Balharry, D., Joy, M., Sheikh, A...., & Lusignan, S. (2022). Methodological Issues in Using a Common Data Model of COVID-19 Vaccine Uptake and Important Adverse Events of Interest: Feasibility Study of Data and Connectivity COVID-19 Vaccines Pharmacovigilance in the United Kingdom. JMIR Formative Research, 6(8), e37821

    https://doi.org/10.2196/37821, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60874
21. Umemneku-Chikere, C., Ayodele, O., Soares, M., Khan, S., Abrams, K., Owen, R., & Bujkiewicz, S. (2022). Comparative review of pharmacological therapies in individuals with HER2-positive advanced breast cancer with focus on hormone receptor subgroups. Frontiers in Oncology, 12

    https://doi.org/10.3389/fonc.2022.943154, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60626
22. Murphy, S., O'Reilly, D., Owen, R., Akbari, A., Lowthian, E., Bedston, S., Torabi, F., Beggs, J., Chuter, A., Lusignan, S., Hobbs, R., Robertson, C., Katikireddi, S., Sheikh, A., & Bradley, D. (2022). Variations in COVID-19 vaccination uptake among people in receipt of psychotropic drugs: cross-sectional analysis of a national population-based prospective cohort. The British Journal of Psychiatry, 221(1), 417-424.

    https://doi.org/10.1192/bjp.2022.36, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59519
23. Maynou, L., Owen, R., Konstant-Hambling, R., Imam, T., Arkill, S., Bertfield, D., Street, A., Abrams, K., & Conroy, S. (2022). The association between frailty risk and COVID-19-associated all-mortality in hospitalised older people: a national cohort study. European Geriatric Medicine, 13, 1149-1157.

    https://doi.org/10.1007/s41999-022-00668-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60326
24. Owen, R., Lyons, J., Akbari, A., Guthrie, B., Agrawal, U., Alexander, D., Azcoaga-Lorenzo, A., Brookes, A., Denaxas, S., Dezateux, C., Fagbamigbe, A., Harper, G., Kirk, P., Özyiğit, E., Richardson, S., Staniszewska, S., McCowan, C., Lyons, R., & Abrams, K. (2022). Temporal sequencing in multimorbidity using population-scale linked data for 1.7 million individuals with 20-year follow-up. Research Square

    https://doi.org/10.21203/rs.3.rs-1537576/v1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59879
25. Delanerolle, G., Williams, R., Stipancic, A., Byford, R., Forbes, A., Anand, S., Bradley, D., Tsang, R., Murphy, S., Akbari, A., Bedston, S., Lyons, R., Owen, R., Beggs, J., Chuter, A., Balharry, D., Joy, M., Sheikh, A., Hobbs, F., & Lusignan, S. (2022). Methodological issues for using a common data model (CDM) of COVID-19 vaccine uptake and important adverse events of interest (AEIs): the Data and Connectivity COVID-19 Vaccines Pharmacovigilance (DaC-VaP) United Kingdom feasibility study. (Preprint). JMIR Formative Research

    https://doi.org/10.2196/preprints.37821, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59635
26. Kerr, S., Joy, M., Torabi, F., Bedston, S., Akbari, A., Agrawal, U., Beggs, J., Bradley, D., Chuter, A., Docherty, A., Ford, D., Hobbs, R., Katikireddi, S., Lowthian, E., Lusignan, S., Lyons, R., Marple, J., McCowan, C., McGagh, D...., & Sheikh, A. (2022). First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales. PLOS Medicine, 19(2), e1003927

    https://doi.org/10.1371/journal.pmed.1003927, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60273
27. Bedston, S., Akbari, A., Jarvis, C., Lowthian, E., Torabi, F., North, L., Lyons, J., Perry, M., Griffiths, L., Owen, R., Beggs, J., Chuter, A., Bradley, D., Lusignan, S., Fry, R., Hobbs, F., Hollinghurst, J., Katikireddi, S., Murphy, S...., & Lyons, R. (2022). COVID-19 vaccine uptake, effectiveness, and waning in 82,959 health care workers: A national prospective cohort study in Wales. Vaccine, 40(8), 1180-1189.

    https://doi.org/10.1016/j.vaccine.2021.11.061, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59218
28. Taylor-Rowan, M., Nafisi, S., Owen, R., Duffy, R., Patel, A., Burton, J., & Quinn, T. (2021). Informant-based screening tools for dementia: an overview of systematic reviews. Psychological Medicine, 53(2), 1-10.

    https://doi.org/10.1017/s0033291721002002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57119
29. Owen, R., Conroy, S., Taub, N., Jones, W., Bryden, D., Pareek, M., Faull, C., Abrams, K., Davis, D., & Banerjee, J. (2021). Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records. Age and Ageing, 50(2), 307-316.

    https://doi.org/10.1093/ageing/afaa167, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60666
30. Lyons, J., Akbari, A., Agrawal, U., Harper, G., Azcoaga-Lorenzo, A., Bailey, R., Rafferty, J., Watkins, A., Fry, R., McCowan, C., Dezateux, C., Robson, J., Peek, N., Holmes, C., Owen, R., Owen, R., Abrams, K., John, A., O'Reilly, D...., & Lyons, R. (2021). Protocol for the development of the Wales Multimorbidity e-Cohort (WMC): data sources and methods to construct a population-based research platform to investigate multimorbidity. BMJ Open, 11(1), e047101

    https://doi.org/10.1136/bmjopen-2020-047101, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56103
31. Owen, R., Bujkiewicz, S., Tincello, D., & Abrams, K. (2020). Multivariate network meta-analysis incorporating class effects. BMC Medical Research Methodology, 20(1)

    https://doi.org/10.1186/s12874-020-01025-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60667
32. Owen, R., Bradbury, N., Xin, Y., Cooper, N., & Sutton, A. (2019). MetaInsight: An interactive web‐based tool for analyzing, interrogating, and visualizing network meta‐analyses using R‐shiny and netmeta. Research Synthesis Methods, 10(4), 569-581.

    https://doi.org/10.1002/jrsm.1373, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60669
33. Owen, R., Cooper, N., Quinn, T., Lees, R., & Sutton, A. (2018). Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for health care policy and decision-making. Journal of Clinical Epidemiology, 99, 64-74.

    https://doi.org/10.1016/j.jclinepi.2018.03.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60670
34. Owen, R., Abrams, K., Mayne, C., Slack, M., & Tincello, D. (2017). Comparison of the effectiveness of repeated injections of onabotulinum toxin A for refractory idiopathic detrusor overactivity: analysis of an open label extension of a randomized trial (the RELAX study). Neurourology and Urodynamics, 36(4), 1201-1207.

    https://doi.org/10.1002/nau.23095, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60671
35. Owen, R., Abrams, K., Mayne, C., Slack, M., & Tincello, D. (2017). Patient factors associated with onabotulinum toxin A treatment outcome in women with detrusor overactivity. Neurourology and Urodynamics, 36(2), 426-431.

    https://doi.org/10.1002/nau.22948, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60672
36. Owen, R., Tincello, D., & Keith, R. (2015). Network Meta-Analysis: Development of a Three-Level Hierarchical Modeling Approach Incorporating Dose-Related Constraints. Value in Health, 18(1), 116-126.

    https://doi.org/10.1016/j.jval.2014.10.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60673
37. Tincello, D., Owen, R., Slack, M., & Abrams, K. (2013). Validation of the Patient Global Impression scales for use in detrusor overactivity: secondary analysis of the RELAX study. BJOG: An International Journal of Obstetrics & Gynaecology, 120(2), 212-216.

    https://doi.org/10.1111/1471-0528.12069, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60674
38. Aldridge, S., Schmidt, A., Owen, R., Dolanski-Aghamanoukjan, L., Mathis-Edenhofer, S., Lyons, R., & Aldridge, S. (2023). Has the COVID-19 pandemic changed non-COVID-19 healthcare utilisation patterns across Europe?. European Journal of Public Health, 33(Supplement_2)

    https://doi.org/10.1093/eurpub/ckad160.1001, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65014
39. Akbari, A., Torabi, F., Bedston, S., Lowthian, E., Abbasizanjani, H., Fry, R., Lyons, J., Owen, R., Khunti, K., & Lyons, R. (n.d.) Developing a research ready population-scale linked data ethnicity-spine in Wales. medRxiv

    https://doi.org/10.1101/2022.11.28.22282810, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62091
40. Aldridge, S., Owen, R., Lyons, R., Schmidt, A., Thißen, M., Bernal-Delgado, E., Estupiñán-Romero, F., González-Galindo, J., Dolanski-Aghamanoukjan, L., Mathis-Edenhofer, S., Buble, T., Križ, K., Vuković, J., , L., Unim, B., & Meulman, I. (n.d.) Has the COVID-19 pandemic changed existing patterns of non-COVID-19 health care utilisation? A retrospective analysis of 6 regions in Europe. European Journal of Public Health (EJPH)

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65539
41. Stannard, S., Berrington, A., Fraser, S., Paranjothy, S., Hoyle, R., Owen, R., Akbari, A., Shiranirad, M., Chiovoloni, R., & Alwan, N. (n.d.) Mapping domains of early-life determinants of future multimorbidity across three UK longitudinal cohort studies. medRxiv

    https://doi.org/10.1101/2024.02.01.24301771, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65591
42. Aldridge, S., Agrawal, U., Murphy, S., Millington, T., Akbari, A., Almaghrabi, F., Anand, S., Bedston, S., Goudie, R., Griffiths, R., Joy, M., Lowthian, E., Lusignan, S., Patterson, L., Robertson, C., Rudan, I., Bradley, D., Lyons, R., Sheikh, A., & Owen, R. (2024). Uptake of COVID-19 vaccinations amongst 3,433,483 children and young people: meta-analysis of UK prospective cohorts. Nature Communications, 15(1)

    https://doi.org/10.1038/s41467-024-46451-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65851

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