Dr Zhidao Xia

Uchafbwyntiau Ymchwil

1. Huang, L., Xia, Z., Wade, D., Liu, J., Zhou, G., Yu, C., Dawes, H., Esser, P., Wei, S., Song, J., & Wade, L. (2024). Knee osteoarthritis pendulum therapy: In vivo evaluation and a randomised, single-blind feasibility clinical trial. Journal of Orthopaedic Translation, 45, 266-276.

   https://doi.org/10.1016/j.jot.2024.02.008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65986

   http://dx.doi.org/10.1016/j.jot.2024.02.008
2. Xia, Z., Ricciardi, B., Liu, Z., Ruhland, C., Ward, M., Lord, A., Hughes, L., Goldring, S., Purdue, E., Murray, D., & Perino, G. (2017). Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty. Nanomedicine: Nanotechnology, Biology and Medicine, 13(3), 1205-1217.

   https://doi.org/10.1016/j.nano.2016.11.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31554
3. Shi, Y., Pan, T., Zhu, W., Yan, C., & Xia, Z. (2020). Artificial bone scaffolds of coral imitation prepared by selective laser sintering. Journal of the Mechanical Behavior of Biomedical Materials, 104, 103664

   https://doi.org/10.1016/j.jmbbm.2020.103664, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53582
4. Francis, W., Owens, S., Kanamarlapudi, V., & Xia, Z. (2021). Role of hypoxia inducible factor 1alpha in cobalt nanoparticle induced cytotoxicity of human THP-1 macrophages. Biomaterials Translational, 2(2), 143-150.

   https://doi.org/10.12336/biomatertransl.2021.02.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57975
5. Li, X., Yan, C., Wang, D., Lu, H., & Xia, Z. (2021). Fabrication of Micro-Nano Bioactive Glass Scaffold Incorporated with Siglec-15 for Bone Repair and Postoperative Treatment of Osteosarcoma. Science of Advanced Materials, 13(8), 1445-1451.

   https://doi.org/10.1166/sam.2021.4000, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58672
6. Liu, Z., Liu, H., Vowden, R., Hughes, L., Qi, D., Francis, W., Perino, G., Pink, R., Xiao, J., Li, B., & Xia, Z. (2023). Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo. Journal of Orthopaedic Translation, 38, 203-212.

   https://doi.org/10.1016/j.jot.2022.10.013, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63234

   http://dx.doi.org/10.1016/j.jot.2022.10.013
7. Rahbari, R., Francis, L., Guy, O., Sharma, S., Ruhland, C., & Xia, Z. (2023). Microneedle-Assisted Transfersomes as a Transdermal Delivery System for Aspirin. Pharmaceutics, 16(1), 57

   https://doi.org/10.3390/pharmaceutics16010057, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65386

   http://dx.doi.org/10.3390/pharmaceutics16010057
8. Konstantinou, D., Lei, M., Xia, Z., & Kanamarlapudi, V. (2014). Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. Cell Biology International, 39(4), 502-507.

   https://doi.org/10.1002/cbin.10409, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19760
9. Williams, A., Flynn, K., Xia, Z., & Dunstan, P. (2016). Multivariate spectral analysis of pH SERS probes for improved sensing capabilities. Journal of Raman Spectroscopy

   https://doi.org/10.1002/jrs.4910, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26714
10. Naderi, N., Wilde, C., Haque, T., Francis, W., Seifalian, A., Thornton, C., Xia, Z., & Whitaker, I. (2014). Adipogenic differentiation of adipose-derived stem cells in 3-dimensional spheroid cultures (microtissue): Implications for the reconstructive surgeon. Journal of Plastic, Reconstructive & Aesthetic Surgery, 67(12), 1726-1734.

    https://doi.org/10.1016/j.bjps.2014.08.013, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18931
11. Day, A., Francis, W., Fu, K., Pieper, I., Guy, O., Xia, Z., Guy, O., Francis, W., & Xia, Z. (2018). Osteogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells on Coralline Hydroxyapatite/Calcium Carbonate Microparticles. Stem Cells International, 2018, 1-9.

    https://doi.org/10.1155/2018/4258613, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46128
12. Perino, G., Sunitsch, S., Huber, M., Ramirez, D., Gallo, J., Vaculova, J., Natu, S., Kretzer, J., Müller, S., Thomas, P., Thomsen, M., Krukemeyer, M., Resch, H., Hügle, T., Waldstein, W., Böettner, F., Gehrke, T., Sesselmann, S., Rüther, W...., & Xia, Z. (2018). Diagnostic guidelines for the histological particle algorithm in the periprosthetic neo-synovial tissue. BMC Clinical Pathology, 18(1)

    https://doi.org/10.1186/s12907-018-0074-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43694
13. Xia, Z., Shi, Y., He, H., Pan, Y., & Liu, C. (2017). Development of Biodegradable Bone Graft Substitutes Using 3D Printing. Developments and Applications of Calcium Phosphate Bone Cements (pp. 517-545). Springer, Singapore

    https://doi.org/10.1007/978-981-10-5975-9_13, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46129
14. Qiu, Y., Wang, X., Zhang, Y., Carr, A., Zhu, L., Xia, Z., & Sabokbar, A. (2013). In vitrotwo-dimensional and three-dimensional tenocyte culture for tendon tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 10(3), E216-E226.

    https://doi.org/10.1002/term.1791, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46152
15. Chaudhury, S., Xia, Z., Thakkar, D., Hakimi, O., & Carr, A. (2016). Gene expression profiles of changes underlying different-sized human rotator cuff tendon tears. Journal of Shoulder and Elbow Surgery, 25(10), 1561-1570.

    https://doi.org/10.1016/j.jse.2016.02.037, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27846
16. Xue, H., Tu, Y., Ma, T., Liu, X., Wen, T., Cai, M., Xia, Z., & Mei, J. (2015). Lactoferrin Inhibits IL-1�-Induced Chondrocyte Apoptosis Through AKT1-Induced CREB1 Activation. Cellular Physiology and Biochemistry, 36(6), 2456-2465.

    https://doi.org/10.1159/000430206, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa24016
17. Cray, J., Yang, Z., Chen, W., Xia, Z., Liu, Y., Peggrem, S., Geng, T., Yang, Z., Li, H., Xu, B., Zhang, C., Triffitt, J., & Zhang, Y. (2015). Local Application of Ibandronate/Gelatin Sponge Improves Osteotomy Healing in Rabbits. PLOS ONE, 10(5), e0125807

    https://doi.org/10.1371/journal.pone.0125807, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa24017
18. Francis, W., Owens, S., Xia, Z., & Kanamarlapudi, V. (2014). The temporal expression of estrogen receptor alpha-36 and runx2 in human bone marrow derived mesenchymal stromal cells during osteogenesis. Biochem Biophys Res Commun

    https://doi.org/10.1016/j.bbrc.2014.09.111, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19126

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=25281901
19. Xia, Z. (2014). Improvement of femoral component size prediction using a C-arm intensifier guide and our established algorithm in unicompartmental knee arthroplasty: a report from a Chinese population. Knee, 21, 435-438.

    https://doi.org/10.1016/j.knee.2013.06.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19125

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=23890472
20. Zhang, Y., Wang, X., Qiu, Y., Cornish, J., Carr, A., & Xia, Z. (2014). Effect of indomethacin and lactoferrin on human tenocyte proliferation and collagen formation in vitro. Biochemical and Biophysical Research Communications, 454(2), 301-307.

    https://doi.org/10.1016/j.bbrc.2014.10.061, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46130
21. Tu, Y., Xue, H., Francis, W., Davies, A., Pallister, I., Kanamarlapudi, V., & Xia, Z. (2013). Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3. Biochemical and Biophysical Research Communications, 441(1), 249-255.

    https://doi.org/10.1016/j.bbrc.2013.10.047, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16395
22. Xia, Z. (2013). Characterization of a biodegradable coralline hydroxyapatite/calcium carbonate composite and its clinical implementation. Biomed Mater, 8(6), 065007

    https://doi.org/10.1088/1748-6041/8/6/065007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19127

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=24288015
23. Qiu, Y., Wang, X., Zhang, Y., Carr, A., Zhu, L., Xia, Z., & Sabokbar, A. (2013). In vitro two-dimensional and three-dimensional tenocyte culture for tendon tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, n/a-n/a.

    https://doi.org/10.1002/term.1791, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16394
24. Yahyouche, A., Xia, Z., Triffitt, J., Czernuszka, J., & Clover, A. (2013). Improved angiogenic cell penetration in vitro and in vivo in collagen scaffolds with internal channels. Journal of Materials Science: Materials in Medicine, 24(6), 1571-1580.

    https://doi.org/10.1007/s10856-013-4912-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16392

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=23890472
25. Xia, Z., Duan, X., Murray, D., Triffitt, J., & Price, A. (2013). A method of isolating viable chondrocytes with proliferative capacity from cryopreserved human articular cartilage. Cell and Tissue Banking, 14(2), 267-276.

    https://doi.org/10.1007/s10561-012-9328-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16393
26. Qiu, Y., Wang, X., Zhang, Y., Carr, A., Zhu, L., Xia, Z., & Sabokbar, A. (2013). In vitrotwo-dimensional and three-dimensional tenocyte culture for tendon tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 10(3), E216-E226.

    https://doi.org/10.1002/term.1791, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27843
27. Qiu, Y., Wang, X., Zhang, Y., Carr, A., Zhu, L., Xia, Z., & Sabokbar, A. (2013). Development of a Refined Tenocyte Differentiation Culture Technique for Tendon Tissue Engineering. Cells Tissues Organs, 197(1), 27-36.

    https://doi.org/10.1159/000341426, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16402
28. Qiu, Y., Wang, X., Zhang, Y., Carr, A., Zhu, L., Xia, Z., & Sabokbar, A. (2012). Development of a refined tenocyte expansion culture technique for tendon tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, n/a-n/a.

    https://doi.org/10.1002/term.1597, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16396
29. Wang, X., Qiu, Y., Triffitt, J., Carr, A., Xia, Z., & Sabokbar, A. (2012). Proliferation and differentiation of human tenocytes in response to platelet rich plasma: An in vitro and in vivo study. Journal of Orthopaedic Research, 30(6), 982-990.

    https://doi.org/10.1002/jor.22016, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16397
30. Xia, Z. (2012). [Effect of different concentrations of dexamethasone on apoptosis and expression of Fas/FasL in human osteoarthritis chondrocytes]..

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46131
31. Yahyouche, A., Xia, Z., Czernuszka, J., & Xia, Z. (2011). Macrophage-mediated degradation of crosslinked collagen scaffolds. Acta Biomaterialia, 7, 278-286.

    https://doi.org/10.1016/j.actbio.2010.08.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10245
32. Xia, Z., Kwon, Y., Mehmood, S., Downing, C., Jurkschat, K., & Murray, D. (2011). Characterization of metal-wear nanoparticles in pseudotumor following metal-on-metal hip resurfacing. Nanomedicine: Nanotechnology, Biology and Medicine, 7(6), 674-681.

    https://doi.org/10.1016/j.nano.2011.08.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10244
33. Wang, X., Qiu, Y., Carr, A., & Xia, Z. (2011). Improved human tenocyte proliferation and differentiation in vitro by optimized silk degumming. Biomedical Materials, 6, 35010

    https://doi.org/10.1088/1748-6041/6/3/035010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10246
34. Xia, Z., Bishop, J., & Xia, Z. (2011). Comprehensive Biotechnology

    https://doi.org/10.1016/B978-0-08-088504-9.00504-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46132
35. Fu, K., Xu, Q., Czernuszka, J., & Xia, Z. (2010). Prolonged osteogenesis from human mesenchymal stem cells implanted in immunodeficient mice by using coralline hydroxyapatite incorporating rhBMP2 microspheres.. J Biomed Mater Res A, 92, 1256-64.

    https://doi.org/10.1002/jbm.a.32453, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10218
36. Lawson, M., Xia, Z., Barnett, B., & Xia, Z. (2010). Differences between bisphosphonates in binding affinities for hydroxyapatite. J Biomed Mater Res B Appl Biomater,, 92, 149-55.

    https://doi.org/10.1002/jbm.b.31500, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10219
37. Fu, K., Xu, Q., Czernuszka, J., McKenna, C., Ebetino, F., Russell, R., Triffitt, J., & Xia, Z. (2010). Prolonged osteogenesis from human mesenchymal stem cells implanted in immunodeficient mice by using coralline hydroxyapatite incorporating rhBMP2 microspheres. Journal of Biomedical Materials Research Part A, 9999A, NA-NA.

    https://doi.org/10.1002/jbm.a.32453, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46133
38. Walpole, A., Xia, Z., Wilson, C., & Xia, Z. (2009). A novel nano-porous alumina biomaterial with potential for loading with bioactive materials.. J Biomed Mater Res A, 90, 46-54.

    https://doi.org/10.1002/jbm.a.32067, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10221
39. Kwon, Y., Xia, Z., Glyn-Jones, S., Beard, D., Gill, H., & Murray, D. (2009). Dose-dependent cytotoxicity of clinically relevant cobalt nanoparticles and ions on macrophagesin vitro. Biomedical Materials, 4(2), 025018

    https://doi.org/10.1088/1748-6041/4/2/025018, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10023
40. Walpole, A., Xia, Z., Wilson, C., Triffitt, J., & Wilshaw, P. (2009). A novel nano-porous alumina biomaterial with potential for loading with bioactive materials. Journal of Biomedical Materials Research Part A, 90A(1), 46-54.

    https://doi.org/10.1002/jbm.a.32067, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46134
41. Xia, Z. (2009). Attachment and proliferation of tenocytes /macrophages on silks with different treatments.

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46135
42. Xia, Z. (2009). Combination of PDGF-BB and bFGF reduces differentiation but maintains proliferation of human tenocytes in low bovine serum culture in vitro.

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46136
43. Kashemirov, B., Bala, J., Chen, X., Ebetino, F., Xia, Z., Russell, R., Coxon, F., Roelofs, A., Rogers, M., & McKenna, C. (2008). Fluorescently Labeled Risedronate and Related Analogues: “Magic Linker” Synthesis. Bioconjugate Chemistry, 19(12), 2308

    https://doi.org/10.1021/bc800369c, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10020
44. Xia, Z., Murray, D., Hulley, P., & Xia, Z. (2008). The viability and proliferation of human chondrocytes following cryopreservation.. J Bone Joint Surg Br, 90, 1245-8.

    https://doi.org/10.1302/0301-620X.90B9.20652, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10220
45. Xia, Z., Locklin, R., & Triffitt, J. (2008). Fates and osteogenic differentiation potential of human mesenchymal stem cells in immunocompromised mice. European Journal of Cell Biology, 87(6), 353

    https://doi.org/10.1016/j.ejcb.2008.02.013, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10021
46. Liu, C., Xia, Z., Han, Z., & Xia, Z. (2008). Novel 3D collagen scaffolds fabricated by indirect printing technique for tissue engineering. J Biomed Mater Res B Appl Biomater,, 85(2), 519-28.

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10022
47. Xia, Z., Murray, D., Hulley, P., Triffitt, J., Price, A., & Xia, Z. (2008). The viability and proliferation of human chondrocytes following cryopreservation. The Journal of Bone and Joint Surgery. British volume, 90-B(9), 1245-1248.

    https://doi.org/10.1302/0301-620X.90B9.20652, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46137
48. RUSSELL, R., XIA, Z., DUNFORD, J., OPPERMANN, U., KWAASI, A., HULLEY, P., KAVANAGH, K., TRIFFITT, J., LUNDY, M., PHIPPS, R., BARNETT, B., COXON, F., ROGERS, M., WATTS, N., EBETINO, F., & Xia, Z. (2007). Bisphosphonates: An Update on Mechanisms of Action and How These Relate to Clinical Efficacy

    https://doi.org/10.1196/annals.1402.089, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46138
49. Liu, C., Xia, Z., Czernuszka, J., & Xia, Z. (2007). Design and Development of Three-Dimensional Scaffolds for Tissue Engineering. Chemical Engineering Research and Design, 85(7), 1051-1064.

    https://doi.org/10.1205/cherd06196, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46139
50. Ye, H., Xia, Z., Ferguson, D., Triffitt, J., & Cui, Z. (2007). Studies on the use of hollow fibre membrane bioreactors for tissue generation by using rat bone marrow fibroblastic cells and a composite scaffold. Journal of Materials Science: Materials in Medicine, 18(4), 641-648.

    https://doi.org/10.1007/s10856-007-2314-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46140
51. Marma, M., Xia, Z., Stewart, C., Coxon, F., Dunford, J., Baron, R., Kashemirov, B., Ebetino, F., Triffitt, J., Russell, R., & McKenna, C. (2007). Synthesis and Biological Evaluation of α-Halogenated Bisphosphonate and Phosphonocarboxylate Analogues of Risedronate. Journal of Medicinal Chemistry, 50(24), 5967-5975.

    https://doi.org/10.1021/jm0702884, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46141
52. Xia, Z. & Triffitt, J. (2006). A review on macrophage responses to biomaterials. Biomedical Materials, 1(1), R1-R9.

    https://doi.org/10.1088/1748-6041/1/1/R01, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46142
53. Adamopoulos, I., Xia, Z., Lau, Y., & Athanasou, N. (2006). Hepatocyte growth factor can substitute for M-CSF to support osteoclastogenesis. Biochemical and Biophysical Research Communications, 350(2), 478-483.

    https://doi.org/10.1016/j.bbrc.2006.09.076, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46143
54. XIA, Z., GROVER, L., HUANG, Y., ADAMOPOULOS, I., GBURECK, U., TRIFFITT, J., SHELTON, R., BARRALET, J., & Xia, Z. (2006). In vitro biodegradation of three brushite calcium phosphate cements by a macrophage cell-line. Biomaterials, 27(26), 4557-4565.

    https://doi.org/10.1016/j.biomaterials.2006.04.030, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46144
55. Xia, Z., Taylor, P., Locklin, R., Gordon, S., Cui, Z., & Triffitt, J. (2006). Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice. Journal of Cellular Biochemistry, 98(4), 966-980.

    https://doi.org/10.1002/jcb.20730, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46145
56. Xia, Z., Huang, Y., Adamopoulos, I., Walpole, A., Triffitt, J., & Cui, Z. (2006). Macrophage-mediated biodegradation of poly(DL-lactide-co-glycolide)in vitro. Journal of Biomedical Materials Research Part A, 79A(3), 582-590.

    https://doi.org/10.1002/jbm.a.30853, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46146
57. Xia, Z., Ye, H., Locklin, R., Ferguson, D., Cui, Z., & Triffitt, J. (2005). Efficient characterisation of human cell–bioceramic interactions in vitro and in vivo by using enhanced GFP-labelled mesenchymal stem cells. Biomaterials, 26(29), 5790-5800.

    https://doi.org/10.1016/j.biomaterials.2005.02.018, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46147
58. Xia, Z. (2004). Innate immune response to human mesenchymal stem cell implantation in immunocompromised mice.

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46148
59. Xia, Z., Ye, H., Choong, C., Ferguson, D., Platt, N., Cui, Z., & Triffitt, J. (2004). Macrophagic response to human mesenchymal stem cell and poly(?-caprolactone) implantation in nonobese diabetic/severe combined immunodeficient mice. Journal of Biomedical Materials Research, 71A(3), 538-548.

    https://doi.org/10.1002/jbm.a.30185, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46149

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