Dr Laura Thomas

• Investigating Mechanisms of Tumorigenesis in Familial Polyposis Syndrome (cyfredol)

  PhD

  Goruchwyliwr arall: Dr Nick Jones

• Genomics for precision medicine-based approaches to intestinal cancer therapy (cyfredol)

  PhD

  Goruchwyliwr arall: Dr James Cronin

• Targeting αβ-hydrolase domain-containing protein 11 (ABHD11) in T-cell acute lymphoblastic leukaemia (cyfredol)

  MPhil

  Goruchwyliwr arall: Dr Nick Jones

• PM-280 Skills for Researchers

  The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.

• PM-300 Medical Genetics

  The course is designed to provide an advanced study of the identification of human genes and the determination of the influence of human genes upon disease and health status. Gene identification provides targets for the development of new pharmaceuticals and the range of variation present in the population.

• PM-317 Genetics of Cancer

  This module will provide students with an advanced understanding about the genetic mechanisms involved in carcinogenesis, and how these underlying processes and molecules affect the human body.

• PM-344 Capstone Project

  The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.

• PM-361 Bioinformatics: From Sequence to Function

  The ever increasing availability of genome sequences and protein structure data demands that molecular biologists are proficient at performing extensive data analyses to guide and support traditional laboratory-based research. This Module will provide the theoretical basis and practical training on computational tools currently used to assemble and interrogate genome sequences, infer gene and protein functions, and to examine protein structure data.

• PM-378 Biomedical Laboratory Techniques

  The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.

• PM-378C Technegau Labordy Biofeddygol

  Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.

• PM-400 Advanced Research Project A

  The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period of time. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices and health informatics. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-405.

• PM-405 Advanced Research Project Dissertation

  The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period. The projects undertaken will fall into one of the current medically-related research themes. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title.

• PMGM00 Bioinformatics for Genome Analysis

  The module will cover the fundamental principles of informatics and bioinformatics applied to clinical genomics, find and use major genomic and genetic data resources; use software packages, in silico tools, databases and literature searches to align sequence data to the reference genome, critically assess, annotate and interpret findings from genetic and genomic analyses. Theoretical sessions will be coupled with practical assignments of analysing and annotating predefined data sets.

• PMGM14 Cancer Genomics

  This module covers the molecular mechanisms that underlie cancer development, growth and metastasis, and the differences between different cancers. It will explore the different molecular and cellular actions of anti-cancer treatments, the genomic factors affecting response and resistance to treatment, and the research approaches to anti-cancer drug design and development. Broad situations which confer a high cancer risk to a person and/or to other members of the same family will be discussed in the context of how genomic information may be integrated into cancer screening programmes. This module will prepare the students to interrogate the cancer data sets from the 100,000 Genomes Project as well as to interrogate cancer genomic datasets in general.

• PMGM17 Dissertation Project

  The module is for students to build on their previous knowledge, skills and experience by undertaking a laboratory based or suitable non-laboratory based project on a specific subject related to genomics.

• PMGM23 Cancer Genomics

  This module covers the molecular mechanisms that underlie cancer development, growth and metastasis, and the differences between different cancers. It will explore the different molecular and cellular actions of anti-cancer treatments, the genomic factors affecting response and resistance to treatment, and the research approaches to anti-cancer drug design and development. Broad situations which confer a high cancer risk to a person and/or to other members of the same family will be discussed in the context of how genomic information may be integrated into cancer screening programmes. This module will also prepare the students to interrogate and interpret various cancer data sets.

• Darlithydd, Prifysgol Abertawe

  Gorffennaf 2020 - Presennol

Mae Laura yn llysgennad STEM ac yn cyflwyno ei hymchwil yn rheolaidd mewn digwyddiadau a drefnir gan Barc Geneteg Cymru.