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BM-M01
Concepts and Context of Biomedical Sciences
This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics:¿¿
- Human Anatomy and Physiology ¿ across the life span¿
- Good laboratory practice and Sustainability¿
- Key principles of cellular pathology, clinical biochemistry, medical microbiology, clinical immunology, clinical genetics and haematology¿
- Quality Management: Internal Quality Control (IQC), External Quality Assessment (EQA) and risk management
This module provides students with an opportunity to further develop and explore the fundamental concepts and context of biomedical sciences across the various discipline subject areas, with a primary focus on developing their technical skill competency, adherence with professional standards, embedding the principles of evidence-based practice and the integration of core biomedical science knowledge using a patient-centred clinical case study approach.
The module will support students to actively engage with real-world case studies to apply the fundamental knowledge and technical skills to develop their diagnostic decision making, understanding of the various analytical techniques and develop a proactive approach to applying their problem-solving skills to complex problems. Throughout the module, the theme of professional development and patient experience is highlighted in a syllabus that is focused on quality assurance, laboratory safety and sustainability, data governance, data interpretation, the principles of Good Laboratory Practice (GLP), adherence to professional practice standards, ethical practice and the multidisciplinary context of healthcare based on a patient-centred approach.
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BM-M04
Clinical Biochemistry - Metabolism and Nutrition
This module offers an in-depth exploration of clinical biochemistry as it relates to nutrition, metabolic disorders, and diagnostic science. It covers essential topics including nutritional requirements, fluid and electrolyte balance, bone and mineral metabolism, lipid metabolism, gastrointestinal disorders, and specific protein analysis. The curriculum extends to the biochemical basis and laboratory diagnosis of diabetes, hypoglycaemia, inherited metabolic disorders, and acid-base disturbances. Emphasis is placed on laboratory roles in clinical diagnosis, sample interpretation, and monitoring treatment strategies. Practical laboratory sessions in lipid analysis and blood gas interpretation complement theoretical knowledge, while the module concludes with foundational toxicology and drug metabolism principles relevant to clinical practice.
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BM-M05
Clinical Biochemistry in Pathology
This module explores the biochemical and diagnostic aspects of major organ systems and disease states, focusing on their laboratory investigation and clinical relevance. Topics include renal function and disorders such as AKI and CKD, liver disease pathology and biomarker interpretation, and the use of cardiac biomarkers in diagnosing cardiovascular conditions. Endocrine system investigations cover reproductive, thyroid, pituitary, and adrenal function, with emphasis on hormone regulation and associated disorders.
Additional lectures address pregnancy biochemistry, cancer biomarkers, and therapeutic drug monitoring (TDM), providing students with a comprehensive understanding of laboratory roles in disease diagnosis, monitoring, and management across a wide range of clinical contexts.
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PM-015
Scientific Skills: Lab to Literature
Academic, scientific, and laboratory skills are essential for success in Higher Education and for maintaining safe, professional laboratory practice. This module will help students to develop the knowledge and confidence to work safely in laboratory settings, with particular emphasis on understanding health and safety protocols, including risk assessments and compliance with COSHH regulations.
Through a series of practical sessions, students will gain hands-on experience with key laboratory techniques such as preparing solutions, identifying the basic composition of unknown solutions containing biomolecules, using various chromatography assays, and constructing standard curves using spectrophotometry. Alongside these practical skills, the module fosters competence in data analysis, performing replicates to ensure reliability of data.
In addition to laboratory training, students will build a robust set of academic skills. Workshops will cover effective literature searching strategies, correct referencing practices, techniques to avoid plagiarism, and the principles of clear and persuasive scientific communication. The module also guides students in developing confidence when presenting their work and in producing structured scientific writing.
Through a combination of interactive workshops and laboratory practical sessions, students will develop both theoretical understanding and practical abilities across core areas of biomedical sciences. Hands-on activities will include analysing experimental data and applying essential laboratory and academic techniques. The module will equip students with a strong scientific foundation, preparing them for more advanced study and professional practice in the biomedical field.
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PM-138
Skills for being a Medical Scientist
The aim of this module is to provide students with an initial experience of what it is to be a modern medical scientist, from the initial experimental planning, to performing experiments within the laboratory with data acquisition and analysis and finally to the communication of scientific findings to a wider audience.
Students will develop basic skill sets in the four most important research skill areas of practical laboratory skills, data analysis, collaboration and communication. The module will be both theoretical and applied, where the student will be instructed in methods essential for data acquisition and data analyses but will also actively participate in the laboratory, using broadly applicable experimental techniques. In addition, students will learn about health and safety within a laboratory environment and the current ethics regulations surrounding the use of humans, human tissue and animals within medical research.
Furthermore, students will develop their communication skill sets not only through essay writing but also will develop their oral presentation skill set and their collaboration skills through a group presentation and tutorial classes.
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PM-138C
Sgiliau ar gyfer Gwyddorau Meddygol
Nod y modiwl hwn yw cynnig profiad cychwynnol i fyfyrwyr o waith gwyddonydd meddygol modern, o gamau cychwynnol cynllunio arbrofion, i gynnal arbrofion mewn labordy ynghyd â chasglu a dadansoddi data ac, yn olaf, gyfleu'r canfyddiadau gwyddonol i gynulleidfa ehangach.
Bydd myfyrwyr yn datblygu set o sgiliau sylfaenol yn y pedwar maes sgiliau ymchwil pwysicaf sef sgiliau labordy ymarferol, dadansoddi data, cydweithio a chyfathrebu. Bydd y modiwl hwn yn un damcaniaethol a chymhwysol, lle bydd myfyrwyr yn cael eu hyfforddi mewn dulliau sy'n hanfodol ar gyfer casglu a dadansoddi data ond hefyd bydd disgwyl iddynt gymryd rhan yn y labordy, gan ddefnyddio dulliau arbrofol â chymhwysiad eang. Yn ogystal, bydd myfyrwyr yn dysgu am iechyd a diogelwch mewn amgylchedd labordy a'r rheoliadau moeseg presennol o ran y defnydd o bobl, meinwe dynol ac anifeiliaid mewn ymchwil feddygol.
Ar ben hynny, bydd myfyrwyr yn datblygu eu set o sgiliau cyfathrebu nid yn unig drwy ysgrifennu traethodau ond byddant hefyd yn datblygu eu sgiliau cyflwyno llafar a'u sgiliau cydweithio drwy gyflwyniad gr¿p a dosbarthiadau tiwtorial.
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PM-150
Introductory Biochemistry
The module provides a broad study of the interactions between chemical processes and biological systems. It addresses the chemical processes used by organisms to utilize chemicals for energy production, structural functions and as building blocks of macromolecules.
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PM-150C
Biocemeg Gyflwyniadol
Mae'r modiwl yn darparu astudiaeth eang o'r rhyngweithiadau rhwng prosesau cemegol a systemau biolegol. Mae'n ymdrin â'r prosesau cemegol a ddefnyddir gan organebau i fanteisio ar gemegau at ddiben cynhyrchu egni, at ddibenion strwythurol ac fel blociau adeiladu macromoleciwlau.
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PM-162
Organic and Analytical Chemistry: an Introduction for Life Sciences
This module covers the fundamentals of organic chemistry, with a focus on stereochemistry and the mechanisms behind organic reactions. Additionally, it introduces analytical chemistry principles, emphasizing key instrumental techniques for both quantitative and qualitative analysis, as well as structure elucidation.
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PM-245
Metabolic Regulation: Enzymes & Signal Transduction
This module reviews the basic elements of enzyme kinetics, including their mechanism and inhibition. The control of enzyme function by allosteric mechanisms is considered together with an appreciation of the significance of sigmoid kinetics. An overview of coenzymes and (metal) co-factors in enzyme function is given together with a description of the role played by vitamins in co-enzyme production.
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PM-254
Doctors, patients & the goals of medicine
The educational intention of the module is to allow the student to consider the contemporary practice of Medicine within the United Kingdom. This will include understanding the professional regulation, financial constraints and societal and personal challenges, within which medicine and other healthcare activities are practiced.
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PM-277
Techniques in Molecular Biology
The module will provide a sound theoretical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, gene expression detection, transcriptomics, proteomics and mass spectrometry.
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PM-277C
Technegau Bioleg Foleciwlaidd
Bydd y modiwl yn cynnig sylfaen ddamcaniaethol gadarn ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoddir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, canfod mynegiad genynnau, trawsgriptomeg, proteomeg a sbectrometreg màs.
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PM-278C
Metabolaeth carbohydrad a lipid
Mae'r modiwl hwn yn darparu archwiliad manwl o'r prosesau metabolig sy'n llywodraethu'r prif mfacrofaetholion, carbohydradau ac asidau brasterog. Mae'n canolbwyntio ar y llwybrau biocemegol canolog lle mae egni sy'n deillio o fwyd yn cael ei drawsnewid yn ATP, sef sail egni sylfaenol y gell. Archwilir llwybrau allweddol fel glycolysis, y cylch asid sitrig, a ffosfforyliad ocsideiddiol yn fanwl.
Bydd y modiwl hefyd yn darparu dealltwriaeth o benodolrwydd meinwe ac organau mewn metaboledd. Mae'r modiwl hefyd yn ymdrin â mewnlifiad a metaboledd glwcos a charbohydradau cyffredin eraill, gan bwysleisio sut cânt eu hintegreiddio i rwydweithiau metabolig canolog. Trafodir llwybrau metabolig carbohydrad amgen a chysylltiedig, gan gynnwys y llwybr ffosffad pentos, llwybr Entner-Doudoroff, a metaboledd glycogen, ynghyd â'u perthnasedd i iechyd a chlefydau.
Yn ogystal â hyn, mae'r modiwl yn cwmpasu ß-ocsideiddiad a biosynthesis asidau brasterog, gyda ffocws ar eu goblygiadau clinigol. Yn olaf, archwilir rolau strwythurol a swyddogaethol siwgrau mewn glycobioleg yn enwedig yng nghyd-destun iechyd a chlefydau.
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PM-280
Skills for Researchers
The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
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PM-285
Metabolic Regulation, Enzymology and Endocrinology
The module begins with consideration of metabolic regulation at the protein level considering practical and theoretical aspects of enzyme kinetics and enzymology principles, including an example of an enzyme catalysed reaction mechanism and cofactors. The module then reviews fundamental metabolism pathways before considering the regulation of these via hormonal control and the processes involved in these regulation mechanisms. The module ends by considering disorders in which alteration in hormone levels and signaling cause dysregulation of biochemical pathways, namely diabetes mellitus and Polycystic Ovarian Syndrome (PCOS).
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PM-285C
Rheoli Metabolaidd, Ensymoleg ac Endocrinoleg
Mae'r modiwl yn dechrau drwy ystyried rheoleiddio metabolaidd ar lefel protein gan ystyried agweddau ymarferol a damcaniaethol ar gineteg ensymau ac egwyddorion ensymoleg, gan gynnwys enghraifft o ddulliau adwaith wedi'i gatalyddu gan ensymau a chyd-ffactorau. Yna mae'r modiwl yn adolygu llwybrau metaboledd sylfaenol cyn ystyried rheoleiddio'r rhain trwy reolaeth hormonaidd a'r prosesau sy'n gysylltiedig â'r mecanweithiau rheoleiddio hyn. Mae'r modiwl yn gorffen trwy ystyried anhwylderau lle mae newid mewn lefelau hormonau a signalau yn achosi camreoleiddio llwybrau biocemegol, sef diabetes mellitus a Syndrom Ofarïaidd Polycystig (PCOS).
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PM-287
Clinical Biochemistry
This module explores the biochemical basis of disease and the clinical application of biochemical tests for diagnosis and monitoring. Students will examine key metabolic pathways, organ function, and molecular disorders, alongside the use and interpretation of biochemical data in a healthcare context. Emphasis is placed on understanding analytical techniques, physiological variation, and the principles of diagnostic testing. Laboratory work and data interpretation exercises develop the skills needed for roles in research, clinical diagnostics, and applied biomedical sciences.
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PM-287C
Biocemeg Glinigol
Mae'r modiwl hwn yn archwilio sail fiocemegol clefydau a chymhwysiad clinigol profion biocemegol ar gyfer diagnosis a monitro. Bydd myfyrwyr yn archwilio llwybrau metabolaidd craidd, swyddogaeth organau, a chlefydau moleciwlaidd, ochr yn ochr â'r ffyrdd y caiff data biocemegol ei ddefnyddio a¿i ddehongli yn y cyd-destun gofal iechyd. Rhoddir pwyslais ar ddeall technegau dadansoddol, amrywiaeth ffisiolegol, ac egwyddorion profi diagnostig. Mae gwaith labordy ac ymarferion dehongli data'n datblygu'r sgiliau sydd eu hangen ar gyfer rolau mewn ymchwil, diagnosteg glinigol, a'r gwyddorau biofeddygol cymhwysol.
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PM-330
Nucleic acids: components, metabolism and modification
The module provides an understanding of the metabolism of nucleic acids and the biological relevance of their natural modification. The use of modified nucleic acid products clinically is also covered.
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PM-344
Capstone Project
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
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PMCB01
Clinical Biochemistry - Metabolism and Nutrition
This module will explore the key clinical biochemical principles that are relevant to the application of the principles of clinical biochemistry to evaluate the function of the various physiological systems, the biochemistry of the processes involved that support life; from the cellular to whole physiological systems and explore how clinical biochemistry can detect pathological dysfunction. It will critically develop your understanding of the various biochemical processes involved in the analytical detection of function and dysfunction within health and disease states across the life span.
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PMGM12
Omics Techniques and their Application to Genomic Medicine
This module explores the state of the art genomics techniques used for DNA sequencing (e.g. targeted approaches, whole exome and whole genome sequencing) and RNA sequencing. This module will include introductory bioinformatics approaches required for the analysis of genomic data, which will provide a solid foundation for the Bioinformatics module. The module will also cover the use of array based methodologies and RNA sequencing in estimating levels of protein expression, micro RNAs and gene manipulation technologies. A comprehensive introduction to metabolomics and proteomics, which are important for the functional interpretation of genomic data and discovery of disease biomarkers will also be included.¿
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PMLM22
Laboratory Measurement Techniques for Medical Sciences
This module will enable students to understand the basic and advanced concepts of laboratory and measurement techniques used in medical sciences, how they may be applied with relevant methods of detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to target molecule characteristics and method application.
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PMRM04
Capstone Research Project
This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study.
