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PM-138C
Sgiliau ar gyfer Gwyddorau Meddygol
Nod y modiwl hwn yw cynnig profiad cychwynnol i fyfyrwyr o waith gwyddonydd meddygol modern, o gamau cychwynnol cynllunio arbrofion, i gynnal arbrofion mewn labordy ynghyd â chasglu a dadansoddi data ac, yn olaf, gyfleu'r canfyddiadau gwyddonol i gynulleidfa ehangach.
Bydd myfyrwyr yn datblygu set o sgiliau sylfaenol yn y pedwar maes sgiliau ymchwil pwysicaf sef sgiliau labordy ymarferol, dadansoddi data, cydweithio a chyfathrebu. Bydd y modiwl hwn yn un damcaniaethol a chymhwysol, lle bydd myfyrwyr yn cael eu hyfforddi mewn dulliau sy'n hanfodol ar gyfer casglu a dadansoddi data ond hefyd bydd disgwyl iddynt gymryd rhan yn y labordy, gan ddefnyddio dulliau arbrofol â chymhwysiad eang. Yn ogystal, bydd myfyrwyr yn dysgu am iechyd a diogelwch mewn amgylchedd labordy a'r rheoliadau moeseg presennol o ran y defnydd o bobl, meinwe dynol ac anifeiliaid mewn ymchwil feddygol.
Ar ben hynny, bydd myfyrwyr yn datblygu eu set o sgiliau cyfathrebu nid yn unig drwy ysgrifennu traethodau ond byddant hefyd yn datblygu eu sgiliau cyflwyno llafar a'u sgiliau cydweithio drwy gyflwyniad gr¿p a dosbarthiadau tiwtorial.
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PM-148
Foundations of Community Medicine
Communities now play a key role in improving and sustaining good health and the delivery of care. Community Medicine is often considered synonymous with Preventative and Social Medicine (PSM), Public Health, and Community Health because of a shared concern with the prevention of disease and promotion of health and wellbeing. This module introduces students to the wide range of approaches encompassed within Community Medicine. These include preventative, promotive, curative and rehabilitative approaches aimed at improving population health through community-based health and care.
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PM-164
Genetics, Genomics & Evolution
The module will provide a foundation in genetics and evolution. Concepts such as DNA discovery, structure and replication, gene transcription and translation, mechanisms of gene transmission, genome organisation, epigenetic modifications and mutations will be covered with an appreciation of how these mechanisms have an impact on human disease and antibiotic resistance. The latter part of the module will start with the work of Plato, Cuvier, Lamarck, Wallace and Darwin and how they (and others) influenced the development of an evolutionary theory framework. Using this knowledge the module will then look at the processes involved in speciation and how they can be applied at both the gene and whole organismal level.
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PM-292
Molecular Evolution
The module aims to critically evaluate concepts and apply scientific methods pertaining to the study of molecular evolution, in prokaryotic and eukaryotic organisms.
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PM-292C
Esblygiad Moleciwlaidd
Mae'r modiwl yn anelu at werthuso'n feirniadol y cysyniadau a chymhwyso dulliau gwyddonol sy'n ymwneud â'r astudiaeth o esblygiad moleciwlaidd , mewn organebau procaryotig ac ewcaryotig.
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PM-317
Genetics of Cancer
This module extensively explores the molecular and genetic foundations underlying key aspects of cancer, including angiogenesis, apoptosis, cell signalling, DNA damage, molecular pathology, invasion and metastasis, inflammation, and the Warburg effect. Expert insights will be shared by a consultant gastroenterologist and a consultant pathologist during select lectures. This approach aims to offer students a well-rounded understanding that integrates academic knowledge, research insights, and practical clinical expertise.
Additionally, the module seeks to broaden students' perspectives by dedicating a final lecture to an individual who shares firsthand experiences of living with cancer. This unique session provides students with valuable insights into the human aspect of the disease, fostering empathy and a deeper appreciation of the patient's journey.
An appreciation for the way in which an individual¿s own genome can influence diagnosis, prognosis and treatment is also included.
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PM-344
Capstone Project
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
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PM-354
Cancer Pharmacology
Cancer remains a significant cause of mortality in the modern world. Current and emerging chemotherapies, and the rationale, experimental, and clinical evidence of the pathways or molecules targeted will be explored. Causes of treatment-related side effects, and the therapies used to address these, will be discussed along with the mechanisms that lead to anti-cancer drug resistance.
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PM-M34
Advanced Research Manuscript
The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period. The projects undertaken will fall into one of the current medically related research themes. Students will employ a range of advanced analytical procedures to investigate a specific topic. Research topics will be assigned that are appropriate to a specific degree title.
This module focuses on developing core research skills, methodological understanding, and supervised project planning, providing a structured introduction to research practice.
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PM-M34C
Llawysgrif Ymchwil Uwch
Mae'r prosiect ymchwil uwch yn elfen allweddol o'r flwyddyn olaf o astudio, gan roi profiad i fyfyrwyr o gynnal ymchwil arloesol yn y Sefydliad Gwyddor Bywyd a'r Ganolfan Nanoiechyd dros gyfnod estynedig. Bydd y prosiectau a wneir yn dod o dan un o'r themâu ymchwil meddygol presennol. Bydd myfyrwyr yn defnyddio ystod o weithdrefnau dadansoddol uwch i ymchwilio i bwnc penodol. Bydd pynciau ymchwil yn cael eu neilltuo sy'n briodol i deitl gradd penodol.
Mae'r modiwl hwn yn canolbwyntio ar ddatblygu sgiliau ymchwil craidd, dealltwriaeth fethodolegol, a chynllunio prosiectau dan oruchwyliaeth, gan gynnig cyflwyniad strwythuredig i ymarfer ymchwil.
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PM-M35
Advanced Research Project
The advanced research project provides students with experience of conducting cutting-edge research over an extended period of time. The project will fall into one of the current medically related research themes; Biomarkers and Genes; Microbes and Immunity; Devices and Health Informatics. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title.
This module builds on PM-M34 by requiring students to undertake a more independent, in-depth research project, with greater emphasis on critical analysis, autonomy, and synthesis of findings
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PM-M35C
Prosiect Ymchwil Uwch
Mae'r prosiect ymchwil uwch yn rhoi profiad i fyfyrwyr o gynnal ymchwil arloesol dros gyfnod estynedig o amser. Bydd y prosiect yn gysylltiedig ag un o'r themâu ymchwil meddygol presennol; Biofarcwyr a Genynnau; Microbau ac Imiwnedd; Dyfeisiau a Gwybodeg Iechyd. Bydd myfyrwyr yn defnyddio ystod o weithdrefnau dadansoddol uwch i ymchwilio i bwnc penodol. Yn ogystal, byddant yn cael profiad o baratoi cynnig ymchwil a chyflwyno eu data mewn amrywiol fformatau. Bydd pynciau ymchwil yn cael eu neilltuo sy'n briodol i deitl gradd penodol.
Mae'r modiwl hwn yn adeiladu ar PM-M34C drwy ofyn i fyfyrwyr ymgymryd â phrosiect ymchwil fanylach, mwy annibynnol, gan bwysleisio'n fwy ar ddadansoddi beirniadol, ymreolaeth a syntheseiddio canfyddiadau.
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PMGM16
Genomics of Common and Rare Inherited Disease
This module examines the clinical features and presentations of both common and rare inherited diseases, emphasising the transformative role of genomics in their understanding and management. It considers perspectives from researchers, clinicians, patients, and families to provide a comprehensive view of the impact of genetic insights. The module also examines traditional and modern approaches to gene discovery, highlighting key techniques and strategies used in the genetic analysis of inherited conditions.
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PMGM17
Research Dissertation
This module provides students with the opportunity to undertake an independent, substantive research project in a topic relevant to genomics. Working under the guidance of an academic supervisor, students will design and conduct a laboratory-based, computational, clinical, or literature-based study. The project will enable students to critically evaluate scientific literature, formulate a research question, develop and apply appropriate methodologies, and analyse and interpret findings. Outcomes will be communicated through a literature review, a research paper prepared in the style of a scientific journal article, and an oral presentation. The dissertation serves as the capstone of the MSc Genomic Medicine, allowing students to demonstrate advanced research competence, critical thinking, and professional skills in preparation for future academic or professional practice.
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PMGM22
Introduction to Human Genetics and Genomics
The Introduction to Human Genetics and Genomics module is a subject-specific module in the MSc Genomic Medicine programme. This unit will provide essential and contemporary knowledge relating to genetic science and genetic disease. The module will prepare participants to understand disease genetics, how genomic medicine can be utilised to elucidate disease mechanisms and biology in the context of genomic medicine. It will provide core knowledge underpinning later modules.¿
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PMGM23
Cancer Genomics
Through the lens of genomics, this module covers the molecular mechanisms that underlie cancer development, growth and metastasis, and the differences between different cancers. It will explore the different molecular and cellular actions of anti-cancer treatments, the genomic factors affecting response and resistance to treatment, and the research approaches to anti-cancer drug design and development. Broad situations which confer a high cancer risk to a person and/or to other members of the same family will be discussed in the context of how genomic information may be integrated into cancer screening programs. This module will also prepare the students to interrogate and interpret various cancer data sets.¿
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PMGM24
Application of Genomics in Infectious Disease
In this module the student will learn about the genomic structure of infectious agents, implication of acquisition or loss of nucleotides, genes and plasmids on pathogenicity, sensitivity of a pathogen to drug treatment and outbreak control. Students will learn about infection as a cause of national and global morbidity and mortality, transmission of human infections: person to person, food and water-borne, sexually transmitted, vector-borne, prokaryotes, their genome, replication and population genetics, genomic characterisation of viruses :DNA and RNA genomes, single- stranded, double stranded, segmented, genomic comparisons of microbial strains in the context of outbreaks and transmissions in hospitals and the community, laboratory diagnosis, including genomic techniques and technologies, and appropriate sample type, analysis and interpretation of genomic data, and the role of bioinformatics, anti-infective drug action, mutation rate and drug resistance, genomic evidence of individual susceptibility to specific infection and the role of genomics in: infectious disease diagnosis, drug selection, resistance, monitoring and epidemic control. The students will also learn how to perform aspects of in-silico analyses on microbial gene sequences, in a workshop setting.¿
