Dr Anna Seager

Rheolwr Diwylliant Ymchwil, Research Engagement & Innovation Services

a.l.seager@abertawe.ac.uk

Siaradwr Cymraeg Canolradd

246
Ail lawr
Adeilad Talbot
Campws Singleton

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

https://orcid.org/0000-0001-8926-5504

Trosolwg

Mae Anna Seager yn Swyddog Ymchwil wedi'i chyflogi ar brosiect BEACON a ariennir gan yr Undeb Ewropeaidd sy'n cysylltu ymchwil, entrepreneuriaeth ac arloesi yn rhanbarth cydgyfeirio de Cymru. Mae ymchwil BEACON Anna wedi amrywio o ddadansoddiad geneteg planhigion sydd wedi'u trin â gwrteithiau i fesur proffiliau tocsicolegol y pathogen gastrig, Cryptosporidiwm. Mae prosiectau ymchwil blaenorol yng ngyrfa Anna wedi cynnwys datblygu offer i leihau defnydd o anifeiliaid mewn profion arbrofol ac ymchwil tocsicoleg (NC3Rs).

Ochr yn ochr â'i rôl ymchwil, mae Anna'n cyfrannu at bortffolio addysgu'r Ysgol Feddygaeth, gan addysgu ar gyrsiau israddedig ac ôl-raddedig, megis Geneteg Canser a Ffarmacoleg a darparu mentora academaidd i fyfyrwyr. Yn 2018, dyfarnodd yr Academi Addysg Uwch gymrodoriaeth i Anna yn seiliedig ar ei hymagwedd wedi'i llywio gan ymchwil at addysg myfyrwyr.

Mae Anna yn llysgennad STEM ymrwymedig sy'n ymwneud â mentrau di-rif i ennyn diddordeb y cyhoedd a phlant mewn ymchwil, gan gynnwys Soapbox Science 2015, Gŵyl Wyddoniaeth Abertawe, Dydd Sadwrn Gwyddoniaeth Wych, Diwrnod Hwyl i'r Teulu Prifysgol Abertawe a Pint of Science 2019.

Drwy gydol ei gyrfa, mae Anna wedi bod yn angerddol am gydraddoldeb, amrywiaeth a chynwysoldeb, a adlewyrchir yn ei rôl wirfoddol barhaus fel arweinydd Athena SWAN yn yr Ysgol Feddygaeth. Mae Athena SWAN yn gynllun cenedlaethol â'r nod o gydnabod problemau ym maes cydraddoldeb a mynd i'r afael â nhw drwy gydnabod na fydd y gymuned academaidd ac addysg uwch yn gallu cyflawni eu potensial llawn oni bai y gallant elwa o ddoniau pawb. Dechreuodd ymrwymiad Anna i Gydraddoldeb, Amrywiaeth a Chynwysoldeb ym Mhrifysgol Abertawe yn 2012 pan ddaeth hi'n aelod o dîm Athena SWAN y Brifysgol ac wedi hynny'n Arweinydd yn nhîm Athena SWAN yr Ysgol Feddygaeth yn 2015. Anna sydd â chyfrifoldeb am y gyfres o seminarau Athena SWAN sy'n cynnal gweithdai ar gyfer staff a myfyrwyr (ar bynciau megis pendantrwydd, dyrchafiadau, rhagfarn ddiarwybod a sgiliau ysgrifennu), ac mae hi'n aelod o Bwyllgor Cydraddoldeb ac Amrywiaeth Ysgol Feddygaeth Prifysgol Abertawe a Grŵp Strategaeth Athena SWAN y Brifysgol.

Meysydd Arbenigedd

• Tocsicoleg
• Ffarmacoleg
• Bioleg Celloedd
• Microsgopeg a delweddu celloedd
• Technegau moleciwlaidd

Uchafbwyntiau Gyrfa

Prif Wobrau

Cafodd cyfraniad personol Anna at Gydraddoldeb, Amrywiaeth a Chynwysoldeb yn y Brifysgol ei gydnabod drwy ddyfarnu Gwobr Mary Williams iddi yn 2019.

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Shah, U., Seager, A., Fowler, P., Doak, S., Johnson, G., Scott, S., Scott, A., & Jenkins, G. (2016). A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 808, 8-19.
https://doi.org/10.1016/j.mrgentox.2016.06.009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa29535
Patni, S., Wynen, L., Seager, A., Morgan, G., White, J., & Thornton, C. (2009). Expression and Activity of Toll-Like Receptors 1–9 in the Human Term Placenta and Changes Associated with Labor at Term. Biology of Reproduction, 80(2), 243-248.
https://doi.org/10.1095/biolreprod.108.069252, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10151
Macfarlane, T., Seager, A., Moller, M., Morgan, G., & Thornton, C. (2010). Thymic stromal lymphopoietin is present in human breast milk. Pediatric Allergy and Immunology, 21(2p2), e454-e456.
https://doi.org/10.1111/j.1399-3038.2009.00916.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10152
Seager, A., Shah, U., Mikhail, J., Nelson, B., Marquis, B., Doak, S., Johnson, G., Griffiths, S., Carmichael, P., Scott, S., Scott, A., Jenkins, G., Jenkins, G., Doak, S., Seager, A., Johnson, G., & Mikhail, J. (2012). Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance. Toxicological Sciences, 128(2), 387-397.
https://doi.org/10.1093/toxsci/kfs152, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10909
http://toxsci.oxfordjournals.org/content/early/2012/04/26/toxsci.kfs152.abstract
Seager, A., Shah, U., Brusehafer, K., Wills, J., Manshian, B., Chapman, K., Thomas, A., Scott, A., Doherty, A., Doak, S., Johnson, G., Jenkins, G., Jenkins, G., Doak, S., Seager, A., Johnson, G., Bruesehafer, K., Shah, U., & Chapman, K. (2014). Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells. Mutagenesis, 29(3), 155-164.
https://doi.org/10.1093/mutage/geu008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa17804
Chapman, K., Wilde, E., Chapman, F., Verma, J., Shah, U., Stannard, L., Seager, A., Tonkin, J., Brown, R., Doherty, A., Johnson, G., Doak, S., & Jenkins, G. (2021). Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action. Archives of Toxicology, 95(1), 321-336.
https://doi.org/10.1007/s00204-020-02902-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55186

Holl Ymchwil

Erthyglau Cylchgronau

Chapman, K., Wilde, E., Chapman, F., Verma, J., Shah, U., Stannard, L., Seager, A., Tonkin, J., Brown, R., Doherty, A., Johnson, G., Doak, S., & Jenkins, G. (2021). Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action. Archives of Toxicology, 95(1), 321-336.
https://doi.org/10.1007/s00204-020-02902-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55186
Shah, U., Seager, A., Fowler, P., Doak, S., Johnson, G., Scott, S., Scott, A., & Jenkins, G. (2016). A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 808, 8-19.
https://doi.org/10.1016/j.mrgentox.2016.06.009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa29535
Seager, A., Shah, U., Brusehafer, K., Wills, J., Manshian, B., Chapman, K., Thomas, A., Scott, A., Doherty, A., Doak, S., Johnson, G., Jenkins, G., Jenkins, G., Doak, S., Seager, A., Johnson, G., Bruesehafer, K., Shah, U., & Chapman, K. (2014). Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells. Mutagenesis, 29(3), 155-164.
https://doi.org/10.1093/mutage/geu008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa17804
Seager, A., Shah, U., Mikhail, J., Nelson, B., Marquis, B., Doak, S., Johnson, G., Griffiths, S., Carmichael, P., Scott, S., Scott, A., Jenkins, G., Jenkins, G., Doak, S., Seager, A., Johnson, G., & Mikhail, J. (2012). Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance. Toxicological Sciences, 128(2), 387-397.
https://doi.org/10.1093/toxsci/kfs152, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10909
http://toxsci.oxfordjournals.org/content/early/2012/04/26/toxsci.kfs152.abstract
Macfarlane, T., Seager, A., Moller, M., Morgan, G., & Thornton, C. (2010). Thymic stromal lymphopoietin is present in human breast milk. Pediatric Allergy and Immunology, 21(2p2), e454-e456.
https://doi.org/10.1111/j.1399-3038.2009.00916.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10152
Patni, S., Wynen, L., Seager, A., Morgan, G., White, J., & Thornton, C. (2009). Expression and Activity of Toll-Like Receptors 1–9 in the Human Term Placenta and Changes Associated with Labor at Term. Biology of Reproduction, 80(2), 243-248.
https://doi.org/10.1095/biolreprod.108.069252, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10151

Modiwlau a Addysgir

PM-317 Genetics of Cancer

This module will provide students with an advanced understanding about the genetic mechanisms involved in carcinogenesis, and how these underlying processes and molecules affect the human body.
PMBM02 Introduction to Biomedical Science Practice in Health Care

The role of Biomedical Science in the delivery and provision of Health Care will be explored and critically evaluated within this module. This module is designed to provide you with the fundamental and principal concepts of Health Care, specifically to support the role of Biomedical Science. It will provide learning activities based around the general themes of Biomedical Science in Health Care, Anatomy and Pathology, Patient Experience, Pharmacology and Professionalism.
PMBM03 Fundamentals of Biomedical Science

This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover key topic areas ranging from Good Laboratory Practice, Biomedical Diagnostics, Pathophysiology, the disciplines in Biomedical Science and the various approaches involved to ensure Quality Control and Laboratory Management.
PMBM03J Fundamentals of Biomedical Science

This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover key topic areas ranging from Good Laboratory Practice, Biomedical Diagnostics, Pathophysiology, the disciplines in Biomedical Science and the various approaches involved to ensure Quality Control and Laboratory Management.
PMRM00 Introduction to the practice of Medical Physicists & Clinical Engineers in Health Care

Provides a broad-based overview of the Medical Physics & Clinical Engineering discipline.

Dr Anna Seager

Cyfeiriad ebost

Welsh language proficiency

Dolenni Ymchwil

Trosolwg

Meysydd Arbenigedd

Uchafbwyntiau Gyrfa

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Holl Ymchwil

Erthyglau Cylchgronau

Modiwlau a Addysgir

PM-317 Genetics of Cancer

PMBM02 Introduction to Biomedical Science Practice in Health Care

PMBM03 Fundamentals of Biomedical Science

PMBM03J Fundamentals of Biomedical Science

PMRM00 Introduction to the practice of Medical Physicists & Clinical Engineers in Health Care