Dr Ann Hunter

Swyddog Ymchwil - Sbectrometreg Màs, Biomedical Sciences

a.p.hunter@abertawe.ac.uk

160
Llawr Gwaelod
Adeilad Grove
Campws Singleton

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

ResearcherID

Trosolwg

Mae Ann yn wyddonydd ymchwil dadansoddol profiadol, sydd â diddordeb arbennig yn natblygiad a chymhwysiad sbectromedreg màs a thechnegau cromatograffaeth i gydraniad uchel a nodweddiadu manwl-gywir sbectrwm eang o gyfansoddion cemegol a biocemegol.

Mae Ann yn rhan o’r gwaith o hyfforddi staff a phartïon allanol yn y maes sbectromedreg màs, ac yn addysgu cyrsiau gradd ac ôl-radd yn yr Ysgol Feddygaeth, yn ogystal â chefnogi gweithgareddau Allgymorth amrywiol ar gyfer disgyblion o oedran ysgol gynradd i Safon Uwch (https://nmsf.swan.ac.uk/assets/documents/) a thu hwnt (https://nmsf.swan.ac.uk/news-and-events/). Ochr yn ochr â’i chydweithwyr yn NMSF a Waters Corp., cyfrannodd at y gwaith o ddatblygu adnodd addysgol ar gyfer israddedigion,

ACQUITY QDa Practical MS Education Package.

Eitem rhif 715005631 Waters Corp (2018).

Waters Corp, Owen RN, Hunter AP, Wyatt MF

Mae Ann yn aelod o’r British Mass Spectrometry Society a’r American Society for Mass Spectrometry.

Uchafbwyntiau Gyrfa

Diddordebau Addysgu

Cemeg Organig: Cyflwyniad i Wyddorau Bywyd.

Dadansoddi Cemegol: Egluro Cyfansoddiad a Strwythur; Cyflwyniad i Wyddorau Bywyd.

Sbectromedreg Màs – yr elfennau sylfaenol a hanfodol.

Rheolaeth Broffesiynol ac arferion labordy.

Datblygiadau mewn Tocsicoleg: Dewis Eich Gwenwyn.

Datblygu a Rheoleiddio Cyffuriau.

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Patel, C., Bassin, J., Scott, M., Flye, J., Hunter, A., Martin, L., & Goyal, M. (2016). Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives. Molecules, 21(7), 861
https://doi.org/10.3390/molecules21070861, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61776
Delgado Gallardo, J., Sullivan, G., TOKARYK, M., Russell, J., Davies, G., Johns, K., Hunter, A., Watson, T., & Sarp, S. (2022). Disposable FFP2 and Type IIR Medical-Grade Face Masks: An Exhaustive Analysis into the Leaching of Micro- and Nanoparticles and Chemical Pollutants Linked to the COVID-19 Pandemic. ACS EST Water, 2(4), 527-538.
https://doi.org/10.1021/acsestwater.1c00319, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59905
Godfrey, R., Dunscombe, J., Gravell, A., Hunter, A., Barrow, M., Van Keulen, G., Desbrow, C., & Townsend, R. (2022). Use of QuEChERS as a manual and automated high-throughput protocol for investigating environmental matrices. Chemosphere, 308, 136313
https://doi.org/10.1016/j.chemosphere.2022.136313, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61153

Holl Ymchwil

Erthyglau Cylchgronau

Godfrey, R., Dunscombe, J., Gravell, A., Hunter, A., Barrow, M., Van Keulen, G., Desbrow, C., & Townsend, R. (2022). Use of QuEChERS as a manual and automated high-throughput protocol for investigating environmental matrices. Chemosphere, 308, 136313
https://doi.org/10.1016/j.chemosphere.2022.136313, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61153
Delgado Gallardo, J., Sullivan, G., TOKARYK, M., Russell, J., Davies, G., Johns, K., Hunter, A., Watson, T., & Sarp, S. (2022). Disposable FFP2 and Type IIR Medical-Grade Face Masks: An Exhaustive Analysis into the Leaching of Micro- and Nanoparticles and Chemical Pollutants Linked to the COVID-19 Pandemic. ACS EST Water, 2(4), 527-538.
https://doi.org/10.1021/acsestwater.1c00319, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59905
Patel, C., Bassin, J., Scott, M., Flye, J., Hunter, A., Martin, L., & Goyal, M. (2016). Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives. Molecules, 21(7), 861
https://doi.org/10.3390/molecules21070861, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61776

Modiwlau a Addysgir

PM-273 Advances in Toxicology: Pick Your Poison

We are surrounded by substances that may do our bodies harm i.e. poisons. The harm these poisons causes depends on our exposure - the dose. The science of toxicology, a discipline that crosscuts biology, chemistry, pharmacology, and medicine, is based on the principle that the dose makes the poison. This module is compulsory for BSc Medical Pharmacology students and acts as a follow on from PM-147 Introduction to Toxicology: The Dose Makes the Poison. This module will provide students with the opportunity to expand their toxicology knowledge and apply it to three distinct fields within toxicology; analytical toxicology, forensic toxicology and clinical toxicology. Students will learn about the experimental procedures and techniques we employ for the isolation and detection of compounds as well as their effects on biological systems. Students will then learn about the role of employing these methods in the field of forensic toxicology and the role of toxicology within the legal system. Within the module, students will also learn about the role of clinical toxicology and patient presentation following poisoning events and the techniques we have for detection and treatment of toxicology within the clinical setting.
PM-355 Drug Development and Regulation

This is an applications and project management driven module designed to provide the student with an introduction to drug development and the key role of separation science and mass spectrometry within the pharmaceutical industry. This module will introduce Good Laboratory, Clinical and Manufacturing Practice (GLP, GCP, GMP), assay validation (as requested by the Food and Drug Administration (FDA)), the need and implementation of SOPs with particular focus on the pharmaceutical and medical industries, and how these correlate with stringent quality control procedures and health and safety existing due to current legislation. The ethical principles of research, including clinical trials and animal research (design, implementation and reporting) will be outlined, as well as the essential nature of the principles of reduction, refinement and replacement for the use of animals in research. Students will also be able to characterize and map the path of a drug from administration, to metabolism and elimination, for critical evaluation of drug design.
PMLM00 Mass Spectrometry - basics and fundamentals

This module will enable students to gain a sound knowledgebase of the basic concepts of mass spectrometry including the individual components, linking to modern separation techniques, instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.
PMLM01 Laboratory Measurement Techniques for Medicinal Chemistry and Nanomedicine

This module will enable students to understand the basic and advanced concepts of measurement techniques used in medicinal chemistry and nanomedicine, how they may be applied with relevant methods of detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to target molecule characteristics and method application.
PMLM22 Laboratory Measurement Techniques for Medical Sciences

This module will enable students to understand the basic and advanced concepts of laboratory and measurement techniques used in medical sciences, how they may be applied with relevant methods of detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to target molecule characteristics and method application.
PMZM00A A general introduction to small molecule mass spectrometry

This module will enable students to gain knowledge of the basic concepts of small molecule mass spectrometry including typical instrumentation, linking to modern separation techniques, principles of valid analytical measurement and instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.
PMZM00B A general introduction to small molecule mass spectometry

This module will enable students to gain knowledge of the basic concepts of small molecule mass spectrometry including typical instrumentation, linking to modern separation techniques, principles of valid analytical measurement and instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.

Dr Ann Hunter

Cyfeiriad ebost

Dolenni Ymchwil

Trosolwg

Uchafbwyntiau Gyrfa

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Holl Ymchwil

Erthyglau Cylchgronau

Modiwlau a Addysgir

PM-273 Advances in Toxicology: Pick Your Poison

PM-355 Drug Development and Regulation

PMLM00 Mass Spectrometry - basics and fundamentals

PMLM01 Laboratory Measurement Techniques for Medicinal Chemistry and Nanomedicine

PMLM22 Laboratory Measurement Techniques for Medical Sciences

PMZM00A A general introduction to small molecule mass spectrometry

PMZM00B A general introduction to small molecule mass spectometry