Dr Ann Hunter

Research Officer - Mass Spectrometry, Biomedical Sciences

a.p.hunter@swansea.ac.uk

Office - 160
Ground Floor
Grove Building
Singleton Campus

Available For Postgraduate Supervision

Research Links

ResearcherID

About

Ann is an experienced analytical research scientist, with a particular interest in the development and application of mass spectrometry (MS) and chromatography techniques to the high resolution and accurate characterisation of a broad spectrum of chemical and biochemical compounds.

Ann is involved in training staff and external parties in MS, and in undergraduate and postgraduate teaching in the Medical School, as well as supporting a range of Outreach activities for students from primary school to A-level age (https://nmsf.swan.ac.uk/assets/documents/) and beyond (https://nmsf.swan.ac.uk/news-and-events/). With her colleagues in NMSF and Waters Corp., she contributed to the development of an educational resource for undergraduates,

ACQUITY QDa Practical MS Education Package.

Item no. 715005631 Waters Corp (2018).

Waters Corp, Owen RN, Hunter AP, Wyatt MF

Ann is a member of the British Mass Spectrometry Society and American Society for Mass Spectrometry.

Career Highlights

Teaching Interests

Organic Chemistry: An Introduction for Life Sciences.

Chemical Analysis: from Composition to Structure Elucidation; an Introduction for Life Sciences.

Mass Spectrometry - basics and fundamentals.

Professional Management and laboratory practice.

A general introduction to small molecule mass spectrometry.

Advances in Toxicology: Pick Your Poison.

Drug Development and Regulation.

Publications

Research Highlights

Patel, C., Bassin, J., Scott, M., Flye, J., Hunter, A., Martin, L., & Goyal, M. (2016). Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives. Molecules, 21(7), 861
https://doi.org/10.3390/molecules21070861, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61776
Delgado Gallardo, J., Sullivan, G., TOKARYK, M., Russell, J., Davies, G., Johns, K., Hunter, A., Watson, T., & Sarp, S. (2022). Disposable FFP2 and Type IIR Medical-Grade Face Masks: An Exhaustive Analysis into the Leaching of Micro- and Nanoparticles and Chemical Pollutants Linked to the COVID-19 Pandemic. ACS EST Water, 2(4), 527-538.
https://doi.org/10.1021/acsestwater.1c00319, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59905
Godfrey, R., Dunscombe, J., Gravell, A., Hunter, A., Barrow, M., Van Keulen, G., Desbrow, C., & Townsend, R. (2022). Use of QuEChERS as a manual and automated high-throughput protocol for investigating environmental matrices. Chemosphere, 308, 136313
https://doi.org/10.1016/j.chemosphere.2022.136313, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61153

All Research

Journal Articles

Godfrey, R., Dunscombe, J., Gravell, A., Hunter, A., Barrow, M., Van Keulen, G., Desbrow, C., & Townsend, R. (2022). Use of QuEChERS as a manual and automated high-throughput protocol for investigating environmental matrices. Chemosphere, 308, 136313
https://doi.org/10.1016/j.chemosphere.2022.136313, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61153
Delgado Gallardo, J., Sullivan, G., TOKARYK, M., Russell, J., Davies, G., Johns, K., Hunter, A., Watson, T., & Sarp, S. (2022). Disposable FFP2 and Type IIR Medical-Grade Face Masks: An Exhaustive Analysis into the Leaching of Micro- and Nanoparticles and Chemical Pollutants Linked to the COVID-19 Pandemic. ACS EST Water, 2(4), 527-538.
https://doi.org/10.1021/acsestwater.1c00319, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59905
Patel, C., Bassin, J., Scott, M., Flye, J., Hunter, A., Martin, L., & Goyal, M. (2016). Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives. Molecules, 21(7), 861
https://doi.org/10.3390/molecules21070861, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61776

Taught Modules

PM-273 Advances in Toxicology: Pick Your Poison

We are surrounded by substances that may do our bodies harm i.e. poisons. The harm these poisons causes depends on our exposure - the dose. The science of toxicology, a discipline that crosscuts biology, chemistry, pharmacology, and medicine, is based on the principle that the dose makes the poison. This module is compulsory for BSc Medical Pharmacology students and acts as a follow on from PM-147 Introduction to Toxicology: The Dose Makes the Poison. This module will provide students with the opportunity to expand their toxicology knowledge and apply it to three distinct fields within toxicology; analytical toxicology, forensic toxicology and clinical toxicology. Students will learn about the experimental procedures and techniques we employ for the isolation and detection of compounds as well as their effects on biological systems. Students will then learn about the role of employing these methods in the field of forensic toxicology and the role of toxicology within the legal system. Within the module, students will also learn about the role of clinical toxicology and patient presentation following poisoning events and the techniques we have for detection and treatment of toxicology within the clinical setting.
PM-355 Drug Development and Regulation

This is an applications and project management driven module designed to provide the student with an introduction to drug development and the key role of separation science and mass spectrometry within the pharmaceutical industry. This module will introduce Good Laboratory, Clinical and Manufacturing Practice (GLP, GCP, GMP), assay validation (as requested by the Food and Drug Administration (FDA)), the need and implementation of SOPs with particular focus on the pharmaceutical and medical industries, and how these correlate with stringent quality control procedures and health and safety existing due to current legislation. The ethical principles of research, including clinical trials and animal research (design, implementation and reporting) will be outlined, as well as the essential nature of the principles of reduction, refinement and replacement for the use of animals in research. Students will also be able to characterize and map the path of a drug from administration, to metabolism and elimination, for critical evaluation of drug design.
PMLM00 Mass Spectrometry - basics and fundamentals

This module will enable students to gain a sound knowledgebase of the basic concepts of mass spectrometry including the individual components, linking to modern separation techniques, instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.
PMLM01 Laboratory Measurement Techniques for Medicinal Chemistry and Nanomedicine

This module will enable students to understand the basic and advanced concepts of measurement techniques used in medicinal chemistry and nanomedicine, how they may be applied with relevant methods of detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to target molecule characteristics and method application.
PMLM22 Laboratory Measurement Techniques for Medical Sciences

This module will enable students to understand the basic and advanced concepts of laboratory and measurement techniques used in medical sciences, how they may be applied with relevant methods of detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to target molecule characteristics and method application.
PMZM00A A general introduction to small molecule mass spectrometry

This module will enable students to gain knowledge of the basic concepts of small molecule mass spectrometry including typical instrumentation, linking to modern separation techniques, principles of valid analytical measurement and instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.
PMZM00B A general introduction to small molecule mass spectometry

This module will enable students to gain knowledge of the basic concepts of small molecule mass spectrometry including typical instrumentation, linking to modern separation techniques, principles of valid analytical measurement and instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.

Dr Ann Hunter

Email address

Research Links

About

Career Highlights

Publications

Research Highlights

All Research

Journal Articles

Taught Modules

PM-273 Advances in Toxicology: Pick Your Poison

PM-355 Drug Development and Regulation

PMLM00 Mass Spectrometry - basics and fundamentals

PMLM01 Laboratory Measurement Techniques for Medicinal Chemistry and Nanomedicine

PMLM22 Laboratory Measurement Techniques for Medical Sciences

PMZM00A A general introduction to small molecule mass spectrometry

PMZM00B A general introduction to small molecule mass spectometry