Microbes and immunity theme encompasses work on inflammation, immunity, microbiology, and infection. We work on a range of diseases and infections that affect humans and animals.
Areas of interest in immunity include the mechanisms of host-pathogen interactions and the role of innate immunity in disease. Allergy and asthma research ranges from translational work on the genetic and immune aspects of asthma through to applied research on improved asthma management. Children and Women’s Health research extends from laboratory through to clinical based projects. Reproductive Immunobiology research focuses on the mechanisms of infection and immunity in the female genital tract, particularly the role of innate immunity in the endometrium and ovary.
Our research includes aspects of virulence and pathogenicity and extends to include genomics to address complex questions in the ecology, epidemiology and evolution of bacteria and of fungi. Others are exploring functional genomics, proteomics and metabolomics in streptomycetes, mycobacteria and fungi and are using microbes to produce chemical entities from biomass for use in industry and health care including by synthetic biology. Research is also directed at eukaryotic cell signalling, developing novel biotechnology approaches to counter a range of microbial infections including malaria, antimicrobial peptides, parasitology, synthetic chemicals towards new antifungal compounds and understanding antibacterial and antifungal drug resistance.
We are also home to the Cryptosporidium Reference Unit and the Toxoplasma Reference Laboratory located in the adjacent Singleton Hospital.