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PM-138
Skills for being a Medical Scientist
The aim of this module is to provide students with an initial experience of what it is to be a modern medical scientist, from the initial experimental planning, to performing experiments within the laboratory with data acquisition and analysis and finally to the communication of scientific findings to a wider audience.
Students will develop basic skill sets in the four most important research skill areas of practical laboratory skills, data analysis, collaboration and communication. The module will be both theoretical and applied, where the student will be instructed in methods essential for data acquisition and data analyses but will also actively participate in the laboratory, using broadly applicable experimental techniques. In addition, students will learn about health and safety within a laboratory environment and the current ethics regulations surrounding the use of humans, human tissue and animals within medical research.
Furthermore, students will develop their communication skill sets not only through essay writing but also will develop their oral presentation skill set and their collaboration skills through a group presentation and tutorial classes.
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PM-161
Cell Biology
Cells are the fundamental units of life, forming the basis of all biological systems. This module provides a comprehensive introduction to cell biology, covering both eukaryotic and prokaryotic cells, their origins, and their evolutionary significance. Students will explore the molecular building blocks of life, gaining insight into how atoms and molecules combine to form essential macromolecules, ultimately giving rise to cells.
The module examines the organization and function of eukaryotic cells, focusing on key organelles such as the nucleus (genetic regulation), mitochondria (energy production), cytoskeleton (structural support and transport), endoplasmic reticulum (protein processing), and Golgi apparatus (lipid processing). Students will also explore cell-to-cell communication via ligands and receptors, as well as the mechanisms of controlled cell death (apoptosis). Additionally, the module covers specialized eukaryotic cells, including those of the nervous and immune systems, as well as the role of stem cells in development.
Prokaryotic cell biology will be explored in depth, covering the structure, function, and diversity of bacteria and archaea. Topics include cell envelope composition, motility, defense mechanisms, communication strategies, and adaptation to extreme environments. The module will also highlight the significance of prokaryotes in health, disease, and biotechnology. Furthermore, students will examine non-living entities such as viruses and bacteriophages, comparing their unique properties with those of eukaryotic and prokaryotic cells.
Through a combination of lectures, laboratory sessions, and workshops, this module will provide students with both theoretical knowledge and practical skills in cell biology, emphasizing its relevance to human health and scientific research.
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PM-161C
Bioleg Celloedd
Celloedd yw unedau sylfaenol bywyd, gan ffurfio sylfaen yr holl systemau biolegol. Mae'r modiwl hwn yn cynnig cyflwyniad cynhwysfawr i fioleg celloedd, gan gynnwys celloedd ewcaryotig a phrocaryotig, eu tarddleoedd, a'u harwyddocâd esblygol. Bydd myfyrwyr yn archwilio seiliau bywyd moleciwlaidd, gan ennill dealltwriaeth o sut mae atomau a moleciwlau yn cyfuno i ffurfio macrofoleciwlau hanfodol, sydd yn y pen draw yn achosi i gelloedd ddatblygu.
Mae'r modiwl yn archwilio trefniadaeth a swyddogaeth celloedd ewcaryotig, gan ganolbwyntio ar organynnau allweddol megis y cnewyllyn (rheoleiddio genetig), mitocondria (cynhyrchu egni), cytosgerbwd (cymorth a chludiant strwythurol), reticwlwm endoplasmig (prosesu protein), a'r organigyn Golgi (prosesu lipidau). Bydd myfyrwyr hefyd yn archwilio cyfathrebu rhwng celloedd drwy gyfrwng ligandau a derbynyddion, yn ogystal â dulliau marwolaeth celloedd a reolir (apoptosis). Yn ogystal, mae'r modiwl yn cynnwys celloedd ewcaryotig arbenigol, gan gynnwys rhai y system nerfol a'r system imiwnedd, yn ogystal â rôl bôn-gelloedd sy'n datblygu.
Archwilir bioleg celloedd procaryotig mewn manylder, gan drafod adeiledd, gweithrediad, ac amrywiaeth bacteria ac archaea. Mae pynciau'n cynnwys cyfansoddiad cell amlen, symudoldeb, mecanweithiau amddiffyn, strategaethau cyfathrebu, ac addasu i amgylcheddau eithafol. Bydd y modiwl hwn hefyd yn amlygu pwysigrwydd procaryotau mewn iechyd, afiechyd, a biotechnoleg. Ar ben hynny, bydd myfyrwyr yn archwilio endidau anfyw megis firysau a bacterioffagau, gan gymharu eu priodoleddau unigryw â phriodoleddau celloedd ewcaryotig a phrocaryotig.
Drwy gyfuniad o ddarlithoedd, sesiynau mewn labordy, a gweithdai, bydd y modiwl hwn yn darparu gwybodaeth ddamcaniaethol a sgiliau ymarferol mewn bioleg celloedd i fyfyrwyr, gan bwysleisio ei berthnasedd i iechyd dynol ac ymchwil wyddonol.
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PM-277
Techniques in Molecular Biology
The module will provide a sound theoretical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, gene expression detection, transcriptomics, proteomics and mass spectrometry.
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PM-277C
Technegau Bioleg Foleciwlaidd
Bydd y modiwl yn cynnig sylfaen ddamcaniaethol gadarn ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoddir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, canfod mynegiad genynnau, trawsgriptomeg, proteomeg a sbectrometreg màs.
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PM-280
Skills for Researchers
The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
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PM-280C
Sgiliau i Ymchwilwyr
Disgwylir i raddedigion gwyddoniaeth modern fod wedi ennill profiad helaeth mewn labordai, ac mae hyn yn bendant yn hanfodol ar gyfer unrhyw fyfyriwr sy'n bwriadu ymgymryd â gyrfa sy'n seiliedig ar ymchwil. Mae Sgiliau i Ymchwilwyr yn rhoi cyfle i fyfyrwyr feithrin y sgiliau craidd i allu cynnal, dadansoddi, dehongli a chyflwyno arbrofion gwyddonol. Treulir cyfran o'r modiwl yn y labordy yn ennill profiad ymarferol. Bydd sgiliau a addysgir yn ystod y modiwl hwn yn ffurfio'r sylfaen ar gyfer gwaith arbrofol yn y dyfodol, gan gynnwys y prosiect yn ystod y flwyddyn olaf. Bydd gan fyfyrwyr y cyfle i roi adborth i gyfoedion ac ymgysylltu ag amrywiaeth o ddeunyddiau dysgu ar-lein.
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PM-317
Genetics of Cancer
This module extensively explores the molecular and genetic foundations underlying key aspects of cancer, including angiogenesis, apoptosis, cell signalling, DNA damage, molecular pathology, invasion and metastasis, inflammation, and the Warburg effect. Expert insights will be shared by a consultant gastroenterologist and a consultant pathologist during select lectures. This approach aims to offer students a well-rounded understanding that integrates academic knowledge, research insights, and practical clinical expertise.
Additionally, the module seeks to broaden students' perspectives by dedicating a final lecture to an individual who shares firsthand experiences of living with cancer. This unique session provides students with valuable insights into the human aspect of the disease, fostering empathy and a deeper appreciation of the patient's journey.
An appreciation for the way in which an individual¿s own genome can influence diagnosis, prognosis and treatment is also included.
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PM-344
Capstone Project
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
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PM-347
Human Immunopathology
The module aims to provide students with a greater understanding of the human immune system and the causes of a range of diseases associated with immune dysfunction including autoimmune diseases, metabolic disorders and neurological conditions.
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PM-378
Biomedical Laboratory Techniques
The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.
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PM-378C
Technegau Labordy Biofeddygol
Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.
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PM-M34
Advanced Research Manuscript
The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period. The projects undertaken will fall into one of the current medically related research themes. Students will employ a range of advanced analytical procedures to investigate a specific topic. Research topics will be assigned that are appropriate to a specific degree title.
This module focuses on developing core research skills, methodological understanding, and supervised project planning, providing a structured introduction to research practice.
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PM-M34C
Llawysgrif Ymchwil Uwch
Mae'r prosiect ymchwil uwch yn elfen allweddol o'r flwyddyn olaf o astudio, gan roi profiad i fyfyrwyr o gynnal ymchwil arloesol yn y Sefydliad Gwyddor Bywyd a'r Ganolfan Nanoiechyd dros gyfnod estynedig. Bydd y prosiectau a wneir yn dod o dan un o'r themâu ymchwil meddygol presennol. Bydd myfyrwyr yn defnyddio ystod o weithdrefnau dadansoddol uwch i ymchwilio i bwnc penodol. Bydd pynciau ymchwil yn cael eu neilltuo sy'n briodol i deitl gradd penodol.
Mae'r modiwl hwn yn canolbwyntio ar ddatblygu sgiliau ymchwil craidd, dealltwriaeth fethodolegol, a chynllunio prosiectau dan oruchwyliaeth, gan gynnig cyflwyniad strwythuredig i ymarfer ymchwil.
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PM-M35
Advanced Research Project
The advanced research project provides students with experience of conducting cutting-edge research over an extended period of time. The project will fall into one of the current medically related research themes; Biomarkers and Genes; Microbes and Immunity; Devices and Health Informatics. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title.
This module builds on PM-M34 by requiring students to undertake a more independent, in-depth research project, with greater emphasis on critical analysis, autonomy, and synthesis of findings
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PM-M35C
Prosiect Ymchwil Uwch
Mae'r prosiect ymchwil uwch yn rhoi profiad i fyfyrwyr o gynnal ymchwil arloesol dros gyfnod estynedig o amser. Bydd y prosiect yn gysylltiedig ag un o'r themâu ymchwil meddygol presennol; Biofarcwyr a Genynnau; Microbau ac Imiwnedd; Dyfeisiau a Gwybodeg Iechyd. Bydd myfyrwyr yn defnyddio ystod o weithdrefnau dadansoddol uwch i ymchwilio i bwnc penodol. Yn ogystal, byddant yn cael profiad o baratoi cynnig ymchwil a chyflwyno eu data mewn amrywiol fformatau. Bydd pynciau ymchwil yn cael eu neilltuo sy'n briodol i deitl gradd penodol.
Mae'r modiwl hwn yn adeiladu ar PM-M34C drwy ofyn i fyfyrwyr ymgymryd â phrosiect ymchwil fanylach, mwy annibynnol, gan bwysleisio'n fwy ar ddadansoddi beirniadol, ymreolaeth a syntheseiddio canfyddiadau.
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PMRM04
Capstone Research Project
This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study.