The course is designed as an introduction to immunology and the human immune system. The course covers
the fundamentals of immunology including functional perturbations associated with disease and
experimental approaches to the study of immunology.
Skills for Researchers
The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
Sgiliau i Ymchwilwyr
Disgwylir i'r myfyriwr gwyddonol modern graddedig ennill profiad helaeth mewn labordy ac mae hyn yn sicr yn hanfodol i unrhyw fyfyriwr sy'n bwriadu dilyn gyrfa yn seiliedig ar ymchwil. Mae Sgiliau i Ymchwilwyr yn rhoi cyfle i fyfyrwyr gaffael y sgiliau craidd i allu cynnal, dadansoddi, dehongli a chyflwyno arbrofion gwyddonol. Bydd cyfran fawr o'r modiwl yn cael ei wario yn y labordy yn ennill profiad ymarferol. Bydd sgiliau a gaffaelir yn y modiwl hwn yn sail ar gyfer gwaith arbrofol yn y dyfodol, gan gynnwys prosiect y flwyddyn olaf. Bydd myfyrwyr yn cael cyfle i roi adborth i gyfoedion ac ymgysylltu ag amrywiaeth o ddeunyddiau dysgu ar-lein.
The course is designed to provide an advanced study of the identification of human genes and the determination of the influence of human genes upon disease and health status. Gene identification provides targets for the development of new pharmaceuticals and the range of variation present in the population.
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a novel research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through creating an introductory presentation on the project background, and a written dissertation and oral presentation on their research conclusions.
The module aims to provide students with a greater understanding of the human immune system and the causes of a range of diseases associated with immune dysfunction including autoimmune diseases, metabolic disorders and neurological conditions.
Biomedical Laboratory Techniques
The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.
Technegau Labordy Biofeddygol
Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.
Advanced Research Project A
The advanced research project is a key component of the final year of study, providing students with experience of
conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period of time.
The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and
Immunity; Devices and health informatics. Students will employ a range of advanced analytical procedures to investigate a specific topic.
In addition, they will gain experience in preparing a research proposal and presenting their data in various formats.
Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student
could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique
of RNA interference.
The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-400
includes the following components: (1) Preparation of a research poster, (2) A 15-minute audio recording giving a presentation of the research area and (3) Oral defence of the project in a viva.
Advanced Research Project Dissertation
The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an extended period. The projects undertaken will fall into one of the current medically-related research themes. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title.
Nanomedicines, pharmaceuticals and advanced therapeutics
This module will explore the history and development of molecular medicines and pharmaceuticals, providing the basis for an advanced understanding of next generation therapeutic approaches. Using landmark technology and chemical development phases informed by separation science and mass spectrometry, the module uses an application driven approach to provide the student with an extensive knowledgebase of drug development, the pharmaceutical industry and nanotherapeutics.
Students will be able to characterize and map the path of a drug from administration, to metabolism and elimination, and critically evaluate drug design and delivery approaches. Traditional small chemical entities used in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. Common target oncology and non-oncology disorders will provide the context; with students encouraged to explore targeted nanoparticle fabrication, drug encapsulation and release profiling, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems. Future molecular medicines such as antibody drug conjugates and kinase inhibitors will be taught by guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.
Postgraduate Taught Masters Dissertation
In this module the student will be able to gain extensive specialist expertise in a chosen topic which could be targeted to their future career in the field of nanomedicine.
Students will be supervised by University academics and/or members of their research and innovation teams. A variety of project types are available that include:
1. Laboratory based experimental research and data analysis (dependant on laboratory access and capacity).
2. Analysis of experimental data originating from the project supervisor¿s laboratory*
3. Meta-analysis of publicly available experimental data*
4. Systematic analysis of publicly available reported data*
*potentially linking with Swansea¿s data health science or clinical trials unit.
Working with a dedicated academic supervisor students will develop a clear research question, experimental plan and derive, analyse and present research data.
The research topic choice will be made in conjunction with the supervisor, based upon novelty, feasibility and practical considerations on a 'first come first served' basis. The final approval of the topic rests with the project supervisor.
The module lead and academic tutor will provide additional support available throughout the module period.
A series of information sessions and engagement events such as the 3 Minute Thesis and employability for an innovative and integral part of this module.
A small number of placement opportunities may arise with external academic and industry partners. These opportunities will be highlighted early in the first semester, with placements, in the event of high demand, based on student academic performance.
Nanomedicines and Therapeutics
The module will explore the history and development of molecular medicines. Using landmark technology and chemical development phases, the traditional small chemical entities using in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. The common target oncology and non oncology disorders will outlined and their respective targets for such medicines detailed alongside drug modes of action and delivery (IV and oral). Further exploration of targeted nanoparticle delivery, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems, will expand the knowledge to future molecular medicines such as antibody drug conjugates and kinase inhibitors. Excitingly the module will include guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.