My research is focused on how to design, synthesise, characterise, assemble, fabricate, operate and develop functional molecular systems (drug delivery vehicles, sensors, motors, actuators, and other molecule-based devices and machines) for different applications.
I did my PhD in supramolecular chemistry at the University of Missouri-St Louis under the supervision of Lee Brammer and postdoctoral research in bioinorganic/bioorganic chemistry at MIT in the laboratory of Steve Lippard. I held posts at the EastCHEM School of Chemistry (Lecturer and Senior Lecturer) of the University of Edinburgh, the School of Engineering (Reader) of the University of Aberdeen, and The Centre for Cooperative Research in Biomaterials (CIC biomaGUNE) where I continue to be Ikerbasque Research Professor and Group Leader of the Theranostic Nanomedicine Laboratory.
I have an interest in integrating chemical, biological and electronic functions; on how to mix molecular building blocks on a single platform; how to retain/enhance function in moving from solution to a surface and from bulk to the nanoscale; surface functionalization of nano- and microparticles and for devices; understanding and resolving the interference between building blocks; molecules, materials and systems that display stimuli-responsiveness.
My lab seeks the development and screening of novel types of organised nano/microscale architectures that are spontaneously self-assembled from multiple components and which when combined together exert special (therapeutic, diagnostic, molecular recognition, sensing or catalytic) functions. An important current focus in the lab is the design, development and study of molecules and nanoparticle constructs for immunomodulation and cancer immunotherapy.