Dr Rowan Brown
Associate Professor
Engineering
Telephone: (01792) 295206
Room: Academic Office - A_016
Ground Floor
Engineering Central
Bay Campus

Specialist Subjects: Stochastic Analysis, Systems Biology, Cytometry, Evolutionary Computing, Intelligent Large-Scale Data Analysis/Simulation, Fractal Generation and Analysis

Systems Cytometry/Microscopy

High throughput experimental techniques, such as flow cytometry, provide detailed information of cell-cycle characteristics for large-scale cellular populations (i.e. > 104 cells). The Systems Cytometry group, formed as an alliance between Swansea and Cardiff universities, employ various stochastic simulation techniques to interpret experimental measurements that allow elucidation and clarification of cellular response and recovery to pharamacodynamic agents' over multiple generations.

Blood Coagulation

Quantification of a blood clot is of extreme importance to the monitoring and treatment of blood diseases and disorders. At present, no universally accepted measure of blood clotting exists, here in Swansea, we have and continue to apply fractal based measures to inform on both incipient and mature clot forms. These measures provide insight into both spatial arrangement of mass and ensuing clot complexity.

Evolutionary Programming

Many population-based evolutionary strategies have their origin in physical-biological processes; here in Swansea we are developing alternative and complementary optimisers' and seek to employ these to solve 'real-life' optimisation problems.

Publications

  1. & Predicting effective control parameters for differential evolution using cluster analysis of objective function features. Journal of Heuristics
  2. & The origin of heterogeneous nanoparticle uptake by cells. Nature Communications 10(1)
  3. & A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells. Archives of Toxicology
  4. & European sea bass show behavioural resilience to near-future ocean acidification. Royal Society Open Science 3(11), 160656
  5. An Analysis of the Practicalities of Multi-Color Nanoparticle Cellular Bar-Coding. Combinatorial Chemistry & High Throughput Screening 19(5), 362-369.

See more...

Teaching

  • EG-353 Research Project

    The module involves the application of scientific and engineering principles to the solution of a practical problem associated with engineering systems and processes. The student will gain experience in working independently on a substantial, individually assigned task, using accepted planning procedures. It will require and develop self-organisation and the critical evaluation of options and results, as well as developing technical knowledge in the chosen topic.

  • EGA215 Rocket and Space Technology

    The module introduces the concepts associated with rocket dynamics, trajectories and orbits of space vehicles and space missions.

  • EGA308 Implant and prosthetic Technology

    This module looks at medical devices implanted within the human body and prosthetics, from two perspectives; i) how to engineer devices/implants to best deliver the required biological function and ii) the impact of implants on the human body.

  • EGNM03 Nanoscale Simulation

    ¿ Quantum mechanics ¿ Bohr model of the atom, Schrodinger equation, energy eigenvalues and wave functions of the hydrogen atom. ¿ Application of quantum mechanics to nano-scale semiconductor structures ¿ Semiconductor band structure, effective mass approximation, quantum wells, wires and dots, density of states for electrons, quantum devices. ¿ Molecular modelling ¿ Basic atomic forces and bonding, small molecule models, proteins, molecular modelling packages. ¿ Transport of particles ¿ Electron transport; diffusion and conduction, nano-fluidics, rate equations and Monte Carlo simulations.

  • PM-230 Selected Medical Diagnostic Techniques

    This module looks at the design and operation of a wide range of instrumentation used to make measurements for diagnostic and monitoring purposes. The emphasis is on the underlying electrical, mechanical, chemical, optical and other engineering principles.

Supervision

  • Validation of a Bespoke Instrumented Mouthguard (current)

    Student name:
    MSc
    Other supervisor: Dr Elisabeth Williams
  • The assembly of novel collagens for regenerative medicine (current)

    Student name:
    MSc
    Other supervisor: Dr Christopher Wright
  • Investigation Head Impact Dynamics in Female Ice Hockey (current)

    Student name:
    MSc
    Other supervisor: Dr Elisabeth Williams
  • Collective movement of cells and fish using computer vision techniques (current)

    Student name:
    PhD
    Other supervisor: Dr Andrew King
    Other supervisor: Dr Ines Fuertbauer
  • Alpine ungulates movement (ALPEN): Quantification of spatiotemporal environmental energetics and social interaction. (current)

    Student name:
    PhD
    Other supervisor: Prof Luca Borger
  • Thermoelectric energy harvesting, design and modelling (current)

    Student name:
    PhD
    Other supervisor: Prof Lijie Li
  • Solving the MOVement Rubik’s Cube: uncovering intra and interspecific«br /»«br /» movement strategies of large herbivores subjected to 6«br /»«br /» major movement constraints (current)

    Student name:
    PhD
    Other supervisor: Prof Luca Borger
  • Collective behaviour: from cells to humans (awarded 2019)

    Student name:
    PhD
    Other supervisor: Dr Andrew King
    Other supervisor: Dr Ines Fuertbauer