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PM-152
Population Genomics
Population genomics is the study of genetic variation within populations and involves the examination of changes in the frequency of gene and alleles across space and time. Concepts such as natural selection, genetic drift, gene pool, genetic diversity, migration and environmental diversity all contribute to create genetic diversity within sub populations. Students will be taught these key concepts along with the real life sub populations examples where genotype variation has led to the diversity in genetics. Such as, the prevalence of disease in the specific populations, the evolution of genetically distinct populations and the genomics behind genetic diversity in sport. This module will take you across the world in multidisciplinary topics and show how genomics is weaved throughout, to create the strengths, weakness, and purely, what makes us who we are.
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PM-261
Pharmacology: Dynamics and Kinetics
Pharmacology is the science of how drugs act on the body and how the body acts on drugs. Pharmacology investigates the chemical and physical properties of drugs, how those properties confer actions on living tissues and how those actions affect health and disease. In this module, students will examine how the body interacts with drugs (pharmacokinetics) and how the drug interacts with the body (pharmacodynamics). Students will learn how the body absorbs, distributed, metabolizes and excretes drugs as well as complex nature of how drugs produce their beneficial, or harmful, effects in living organisms.
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PM-344
Capstone Project
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
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PM-366
Teaching Science
This module is for students with an interest in teaching, science communication, and medicine. Students will complete an enquiry-based research project, based within the field of pedagogy or science communication, with guidance from an academic supervisor. Projects may be completed in collaboration with local schools/colleges, community groups, science outreach programmes (e.g. Oriel Science), in clinical/patient settings, or within Higher Education. Students will engage with workshops and digital resources to introduce various themes surrounding pedagogy and science communication to prepare them for their research project. Students will be required to critically analyse their research findings and produce a teaching or outreach activity/resource. Students will refine their oral and written communication skills to graduate level through an oral presentation and dissertation.
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PMGM00
Bioinformatics for Genome Analysis
The module will cover the fundamental principles of informatics and bioinformatics applied to clinical genomics, find and use major genomic and genetic data resources; use software packages, in silico tools, databases and literature searches to align sequence data to the reference genome, critically assess, annotate and interpret findings from genetic and genomic analyses. Theoretical sessions will be coupled with practical assignments of analysing and annotating predefined data sets.
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PMGM11
Introduction to Human Genetics and Genomics
The Introduction to Human Genetics and Genomics module is a subject-specific module in the MSc Genomic Medicine programme. This unit will provide essential and contemporary knowledge relating to genetic science and genetic disease. The module will prepare participants to understand disease genetics, how genomic medicine can be utilised to elucidate disease mechanisms and biology in the context of genomic medicine. It will provide core knowledge underpinning later modules.
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PMGM14
Cancer Genomics
This module covers the molecular mechanisms that underlie cancer development, growth and metastasis, and the differences between different cancers. It will explore the different molecular and cellular actions of anti-cancer treatments, the genomic factors affecting response and resistance to treatment, and the research approaches to anti-cancer drug design and development. Broad situations which confer a high cancer risk to a person and/or to other members of the same family will be discussed in the context of how genomic information may be integrated into cancer screening programmes. This module will prepare the students to interrogate the cancer data sets from the 100,000 Genomes Project as well as to interrogate cancer genomic datasets in general.
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PMGM16
Genomics of Common and Rare Inherited Disease
This module will provide an introduction to the clinical presentation and manifestations of rare inherited and common diseases, and considers the patient and family perspective with respect to the role and impact of genomics. It reviews traditional and current strategies and techniques used to identify genes responsible for both common multifactorial and rare inherited diseases.
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PMGM17
Dissertation Project
The module is for students to build on their previous knowledge, skills and experience by undertaking a laboratory based or suitable non-laboratory based project on a specific subject related to genomics.
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PMGM22
Introduction to Human Genetics and Genomics
The Introduction to Human Genetics and Genomics module is a subject-specific module in the MSc Genomic Medicine programme. This unit will provide essential and contemporary knowledge relating to genetic science and genetic disease. The module will prepare participants to understand disease genetics, how genomic medicine can be utilised to elucidate disease mechanisms and biology in the context of genomic medicine. It will provide core knowledge underpinning later modules.