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PM-138
Skills for being a Medical Scientist
The aim of this module is to provide students with an initial experience of what it is to be a modern medical scientist, from the initial experimental planning, to performing experiments within the laboratory with data acquisition and analysis and finally to the communication of scientific findings to a wider audience.
Students will develop basic skill sets in the four most important research skill areas of practical laboratory skills, data analysis, collaboration and communication. The module will be both theoretical and applied, where the student will be instructed in methods essential for data acquisition and data analyses but will also actively participate in the laboratory, using broadly applicable experimental techniques. In addition, students will learn about health and safety within a laboratory environment and the current ethics regulations surrounding the use of humans, human tissue and animals within medical research.
Furthermore, students will develop their communication skill sets not only through essay writing but also will develop their oral presentation skill set and their collaboration skills through a group presentation and tutorial classes.
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PM-138C
Sgiliau ar gyfer Gwyddorau Meddygol
Nod y modiwl hwn yw cynnig profiad cychwynnol i fyfyrwyr o waith gwyddonydd meddygol modern, o gamau cychwynnol cynllunio arbrofion, i gynnal arbrofion mewn labordy ynghyd â chasglu a dadansoddi data ac, yn olaf, gyfleu'r canfyddiadau gwyddonol i gynulleidfa ehangach.
Bydd myfyrwyr yn datblygu set o sgiliau sylfaenol yn y pedwar maes sgiliau ymchwil pwysicaf sef sgiliau labordy ymarferol, dadansoddi data, cydweithio a chyfathrebu. Bydd y modiwl hwn yn un damcaniaethol a chymhwysol, lle bydd myfyrwyr yn cael eu hyfforddi mewn dulliau sy'n hanfodol ar gyfer casglu a dadansoddi data ond hefyd bydd disgwyl iddynt gymryd rhan yn y labordy, gan ddefnyddio dulliau arbrofol â chymhwysiad eang. Yn ogystal, bydd myfyrwyr yn dysgu am iechyd a diogelwch mewn amgylchedd labordy a'r rheoliadau moeseg presennol o ran y defnydd o bobl, meinwe dynol ac anifeiliaid mewn ymchwil feddygol.
Ar ben hynny, bydd myfyrwyr yn datblygu eu set o sgiliau cyfathrebu nid yn unig drwy ysgrifennu traethodau ond byddant hefyd yn datblygu eu sgiliau cyflwyno llafar a'u sgiliau cydweithio drwy gyflwyniad gr¿p a dosbarthiadau tiwtorial.
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PM-143
Academic support and professional development
This is a non-credit bearing module, which aims to provide key academic support to students during their first semester at Swansea University. It will help with the transition into university life and support students to make the most out of their time at university. The module will cover vital academic skills needed to succeed, as well as provide key information around student support, the academic community, maintaining academic integrity, and career planning. The information will complement what is delivered as part of the academic program to support professional and academic development.
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PM-243
Clinical Biochemistry & Physiology
The module begins with a discussion of selected metabolic disorders of carbohydrate metabolism and their pathological consequences with particular emphasis on diabetes mellitus. The molecular mechanisms underlying polycystic ovarian syndrome are then considered. Next, there will be a discussion of the analytical tests used by the NHS to diagnose and monitor diseases such as diabetes (for instance the glycated haemoglobin or Hba1c test) how the test(s) can be affected by haemoglobinopathies and the length of time that has elapsed since someone has taken their medication. Finally the module reviews mechanisms of protein transport and their relevance to storage diseases.
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PM-245
Metabolic Regulation: Enzymes & Signal Transduction
This module reviews the basic elements of enzyme kinetics, including their mechanism and inhibition. The control of enzyme function by allosteric mechanisms is considered together with an appreciation of the significance of sigmoid kinetics. An overview of coenzymes and (metal) co-factors in enzyme function is given together with a description of the role played by vitamins in co-enzyme production.
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PM-277
Techniques in Molecular Biology
The module will provide a sound theoretical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, gene expression detection, transcriptomics, proteomics and mass spectrometry.
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PM-277C
Technegau Bioleg Foleciwlaidd
Bydd y modiwl yn cynnig sylfaen ddamcaniaethol gadarn ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoddir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, canfod mynegiad genynnau, trawsgriptomeg, proteomeg a sbectrometreg màs.
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PM-278
Carbohydrate and lipid metabolism
This module provides an in-depth exploration of the metabolic processes governing the major macronutrients carbohydrates and fatty acids. It focuses on the central biochemical pathways through which energy derived from food is converted into ATP, the cell¿s primary energy currency. Key pathways such as glycolysis, the citric acid cycle, and oxidative phosphorylation are examined in detail.
The module will also provide an understanding of tissue and organ specificity in metabolism. The module also covers the uptake and metabolism of glucose and other common carbohydrates, emphasizing their integration into central metabolic networks. Alternative and linked carbohydrate metabolic pathways, including the pentose phosphate pathway, the Entner-Doudoroff pathway, and glycogen metabolism are discussed, along with their relevance to health and disease.
In addition, the module covers the ß-oxidation and biosynthesis of fatty acids, with a focus on its clinical implications. Finally, the structural and functional roles of sugars in glycobiology are explored, particularly in the context of health and disease.
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PM-280
Skills for Researchers
The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
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PM-285
Metabolic Regulation, Enzymology and Endocrinology
The module begins with consideration of metabolic regulation at the protein level considering practical and theoretical aspects of enzyme kinetics and enzymology principles, including an example of an enzyme catalysed reaction mechanism and cofactors. The module then reviews fundamental metabolism pathways before considering the regulation of these via hormonal control and the processes involved in these regulation mechanisms. The module ends by considering disorders in which alteration in hormone levels and signaling cause dysregulation of biochemical pathways, namely diabetes mellitus and Polycystic Ovarian Syndrome (PCOS).
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PM-285C
Rheoli Metabolaidd, Ensymoleg ac Endocrinoleg
Mae'r modiwl yn dechrau drwy ystyried rheoleiddio metabolaidd ar lefel protein gan ystyried agweddau ymarferol a damcaniaethol ar gineteg ensymau ac egwyddorion ensymoleg, gan gynnwys enghraifft o ddulliau adwaith wedi'i gatalyddu gan ensymau a chyd-ffactorau. Yna mae'r modiwl yn adolygu llwybrau metaboledd sylfaenol cyn ystyried rheoleiddio'r rhain trwy reolaeth hormonaidd a'r prosesau sy'n gysylltiedig â'r mecanweithiau rheoleiddio hyn. Mae'r modiwl yn gorffen trwy ystyried anhwylderau lle mae newid mewn lefelau hormonau a signalau yn achosi camreoleiddio llwybrau biocemegol, sef diabetes mellitus a Syndrom Ofarïaidd Polycystig (PCOS).
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PM-319
Membranes and Energy Transduction
An appreciation of the molecular architecture of energy-conserving membranes is provided together with an understanding of the molecular mechanisms involved in energy transduction. The course also provides an understanding of the structure and properties of membranes, the lipids contained within them and the techniques used to study them.
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PM-331
Membrane Trafficking
The module provides an understanding of the subcellular organelles, the regulation of their biosynthesis and how
impairment of this process leads to disease.
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PM-344
Capstone Project
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
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PMRM04
Capstone Research Project
This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study.
