Professor Yuqin Wang
Professor
Biomedical Sciences
Telephone: (01792) 602730
Room: Academic Office - 305
Third Floor
Institute of Life Science 1
Singleton Campus

Publications

  1. Robertson, K., Hsieh, W., Forster, T., Blanc, M., Lu, H., Crick, P., Yutuc, E., Watterson, S., Martin, K., Griffiths, S., Enright, A., Yamamoto, M., Pradeepa, M., Lennox, K., Behlke, M., Talbot, S., Haas, J., Dölken, L., Griffiths, W...., & Ghazal, P. An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway. PLOS Biology, 14(3), e1002364
  2. Kurowska-Stolarska, M., Hasoo, M., Welsh, D., Stewart, L., McIntyre, D., Morton, B., Johnstone, S., Miller, A., Asquith, D., Millar, N., Millar, A., Feghali-Bostwick, C., Hirani, N., Crick, P., Wang, Y., Griffiths, W., McInnes, I., & McSharry, C. The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. Journal of Allergy and Clinical Immunology, 139(6), 1946-1956.
  3. Griffiths, W., Ogundare, M., Meljon, A., Wang, Y., & Wang, Y. Mass Spectrometry Handbook
  4. Griffiths, W., Wang, Y., & Wang, Y. The Importance of Steroidomics in the Study of Neurodegenerative Disease and Ageing. Combinatorial Chemistry & High Throughput Screening, 12(2), 212-228.
    http://www.scopus.com/inward/record.url?eid=2-s2.0-64549148453&partnerID=MN8TOARS

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Teaching

  • PM-344 Capstone Project

    The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to medical science. It will ask a novel research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through creating an introductory presentation on the project background, and a written dissertation and oral presentation on their research conclusions.

  • PMLM02 LC/MS Applications I: Proteomics

    Proteomics sample preparation and separation: protein extraction from cell and tissue, 1D and 2D gel electrophresis, protein digestion (in gel and in solution), peptide separation by SCX and RP-HPLC Mass Spectrometry analysis: peptide fragmentation via CID, LC-MS/MS, interpretation of CID spectrum of peptide Protein identification by database search: principle of database search, software for database search, interpretation of the results Quantitative proteomics: 2D gel ¿based protein quantification, MS-based protein quantification Characterization PTM by mass spectrometry Sample preparation and analysis of phosphoproteome: enrichment of phosphoproteins or phosphopeptides, interpretation CID spectrum of phosphopeptide and identification of phosphorylation sites

  • PMLM05 LC/MS Applications IV: Medical and life sciences

    Students will have the opportunity to gain extensive knowledge of the role mass spectrometry plays in biomarker discovery (proteins and small molecules).with its application to clinical diagnosis including the analysis of carbohydrates, glycoproteins and nucleic acids using activity-based proteomics and techniques for affinity pull-down.

  • PMLM09 Dissertation: MS experimental project.

    Students will have the opportunity to join an established research group to work in a modern and well equipped laboratory or alternatively undertake a suitable non-laboratory based project. In this module the student will be able to gain extensive `hands on¿ specialist expertise in a chosen topic which could be targeted to their future career in the field of mass spectrometry.

Supervision

  • “Lipid Biomarker Discovery in Neurodegenerative Diseases” (current)

    PhD
    Other supervisor: Prof William Griffiths
    Other supervisor: Prof Michael Gravenor
    Other supervisor: Prof Yuqin Wang
  • Inhibiting IL-17 Production by Blocking Endogenous RORγt Agonists for the Treatment of Autoimmune Diseases (current)

    PhD
    Other supervisor: Prof William Griffiths
    Other supervisor: Dr Jonathan Mullins
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Prof Yuqin Wang
  • Development of Assays for Vitamins D and other Sterols using GC-TOF-MS and LC-MS (current)

    PhD
    Other supervisor: Prof Yuqin Wang
    Other supervisor: Prof William Griffiths
  • Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicles Generation and their Cellular Effects (current)

    PhD
    Other supervisor: Prof Yuqin Wang
    Other supervisor: Prof Venkat Kanamarlapudi
  • Models and Methods to Identify Biomarkers to Predict Bacterial Sepsis (awarded 2020)

    PhD
    Other supervisor: Prof Thomas Humphrey
    Other supervisor: Prof William Griffiths
    Other supervisor: Prof Yuqin Wang
    Other supervisor: Dr Thomas Wilkinson
  • 'Development of mass spectrometry based reference methods for the measurement of 25-hydroxyvitamins D2 and D3 and the discovery of related molecules in human serum' (awarded 2017)

    PhD
    Other supervisor: Prof Yuqin Wang
    Other supervisor: Prof William Griffiths
  • 'Lipidomic analysis of sterols in Human T Helper cells' (awarded 2017)

    PhD
    Other supervisor: Prof William Griffiths
    Other supervisor: Prof Yuqin Wang