Professor Catherine Thornton

Professor Catherine Thornton
Personal Chair
Medicine
Telephone: (01792) 602122
Room: Academic Office - 214
Second Floor
Institute of Life Science 1
Singleton Campus

Publications

  1. A high-throughput serum Raman spectroscopy platform and methodology for colorectal cancer diagnostics. Analyst
  2. & Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation. Frontiers in Immunology 8
  3. & Ovine leukocyte microparticles generated by the CentriMag ventricular assist device in vitro. Artificial Organs
  4. & The effect of ventricular assist device-associated biomaterials on human blood leukocytes. Journal of Biomedical Materials Research Part B: Applied Biomaterials
  5. & Expression and function of NOD-like receptors by human term gestation-associated tissues. Placenta 58, 25-32.

See more...

Teaching

  • PM-249 Human Immunology

    The course is designed as an introduction to immunology and the human immune system. The course covers the fundamentals of immunology including functional perturbations associated with disease and experimental approaches to the study of immunology.

  • PM-304 Biomolecular Research Project

    *

  • PM-341 Human Biology and the Environment

    This module is intended to provide an understanding of how our environmental factors impact on key aspects of human biology. Various environmental factors such as diet, stress, and pollution will be considered with a focus on their effects on epigenetics, inflammation, gut microbiota, mitochondrial health, and oxidative stress in non-communicable diseases in particular (e.g. chronic respiratory disease, cancer and metabolic disorders). The effect of extreme environments (e.g. altitude, space) and ageing on multiple organ systems will be considered. Students will gain practical experience in communicating these issues to scientific and non-scientific audiences.

  • PM-344 Capstone Project

    The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project. Depending on the student's employability strand within the programme, the project may be laboratory, data, or education-based, but it will always involve a research question that is drawn from the literature, focused on a topic relevant to medical science. It will ask a novel research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through creating an introductory presentation on the project background, and a written dissertation and oral presentation on their research conclusions.

  • PM-347 Human Immunopathology

    The module aims to provide students with a greater understanding of the human immune system and the causes of a range of diseases associated with immune dysfunction including autoimmune diseases, metabolic disorders and neurological conditions.

  • PMLM01 Separation science and sample handling

    This module will enable students to understand the basic and advanced concepts of separation science, how it is integrated with several forms of compound detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to compound chemical characteristics and method application.

  • PMLM05 LC/MS Applications IV: Medical and life sciences

    Students will have the opportunity to gain extensive knowledge of the role mass spectrometry plays in biomarker discovery (proteins and small molecules).with its application to clinical diagnosis including the analysis of carbohydrates, glycoproteins and nucleic acids using activity-based proteomics and techniques for affinity pull-down.

Supervision

  • The X4A trial: exercise for Asthma (current)

    Student name:
    PhD
    Other supervisor: Prof Gareth Stratton
    Other supervisor: Prof Gwyneth Davies
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Melitta Mcnarry
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Prof Kenith Meissner
    Other supervisor: Prof Peter Dunstan
  • Raman spectroscopy and colorectal cancer: towards early diagnosis and personalised medicine (current)

    Student name:
    PhD
    Other supervisor: Prof Peter Dunstan
    Other supervisor: Prof Catherine Thornton
  • Assessing the Role of the Ghrelin-axis in Extra-Hypothalamic Brain Function (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Jeffrey Davies
  • Ghrelin AMPK mediated mitochondrial dynamics (current)

    Student name:
    MSc
    Other supervisor: Dr Alwena Morgan
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Jeffrey Davies
  • Maternal Immunological Adaptation to Pregnancy (current)

    Student name:
    MPhil
    Other supervisor: Dr James Cronin
    Other supervisor: Prof Catherine Thornton
  • Characterisation of proteins by Raman Spectroscopy and linkage to performance of commercial immunoassays. (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Prof Peter Dunstan
  • Investigation of Candida diversity in an infertile cohort using next generation genetic analysis (current)

    Student name:
    PhD
    Other supervisor: Prof Paul Dyson
    Other supervisor: Prof Catherine Thornton
  • Inhibiting IL-17 Production by Blocking Endogenous RORγt Agonists for the Treatment of Autoimmune Diseases (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Prof William Griffiths
    Other supervisor: Dr Jonathan Mullins
    Other supervisor: Prof Yuqin Wang
  • Regulation of Metabolism in Multiple Myeloma (MM) in Humans (current)

    Student name:
    PhD
    Other supervisor: Dr James Cronin
    Other supervisor: Prof Catherine Thornton
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Dr Ed Dudley
    Other supervisor: Prof Catherine Thornton
  • Disrupting the diagnostic paradigm for gestational diabetes using blood-based Raman spectroscopy. (current)

    Student name:
    PhD
    Other supervisor: Dr Ed Dudley
    Other supervisor: Prof Catherine Thornton
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Deb Roy
  • no changes required to the thesis title (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Ed Dudley
  • 3D Bioprinting Facial Cartilage Using Tissue Specific Stem/Progenitor Cells And Novel Nanocellulose Bioinks (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Prof Iain Whitaker
  • 'Assessing the effects of a viral mimic Poly (I:C) on insect (Galleria mellonella) innate immunity' (awarded 2018)

    Student name:
    MRes
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Christopher Coates
  • 'Natural and Synthetic GHSR1a Agonists as Neuroprotective Agents in Models of Parkinson's Disease' (awarded 2018)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Jeffrey Davies
  • 'Impact of ventricular assist devices on the activity of white blood cells and the implications for device design and testing.' (awarded 2018)

    Student name:
    PhD
    Other supervisor: Dr Karl Hawkins
    Other supervisor: Prof Catherine Thornton
  • 'Determining the bioenergetic capacity of insect (Galleria mellonella) haemocytes' (awarded 2018)

    Student name:
    MRes
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Christopher Coates