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Institute of Life Science 2 Internal Atrium

Miss Samantha Thomas

Research Assistant, Medicine

+44 (0) 1792

samantha.j.thomas@swansea.ac.uk

Basic Welsh Speaker

About

Samantha is currently based at ReNeuron as part of the RISE project, where her current research focuses on exosomes, and their development as a clinical therapeutic in collaboration with Ig Innovations and the Reproductive Biology and Gynaecological Oncology (RBGO) research group at Swansea University. Other research interests include the role of stress on female infertility, Polycystic Ovary Syndrome (PCOS), endometriosis, unexplained infertility and gynaecological cancers.

Areas Of Expertise

Extracellular vesicles and Exosomes
Reproductive Biology
Gynaecological Oncology

Career Highlights

Teaching Interests

Teaching Interests

Samantha has taught on the PNM11, Nanomedicine and advanced therapeutics module. She has also presented as a guest lecturer on the PM-358 Tissue Engineering and Regenerative Medicine module for the BSc course in Genetics and/or Biochemistry.

Taught Modules

PMNM11 Nanomedicines, pharmaceuticals and advanced therapeutics

This module will explore the history and development of molecular medicines and pharmaceuticals, providing the basis for an advanced understanding of next generation therapeutic approaches. Using landmark technology and chemical development phases informed by separation science and mass spectrometry, the module uses an application driven approach to provide the student with an extensive knowledgebase of drug development, the pharmaceutical industry and nanotherapeutics. Students will be able to characterize and map the path of a drug from administration, to metabolism and elimination, and critically evaluate drug design and delivery approaches. Traditional small chemical entities used in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. Common target oncology and non-oncology disorders will provide the context; with students encouraged to explore targeted nanoparticle fabrication, drug encapsulation and release profiling, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems. Future molecular medicines such as antibody drug conjugates and kinase inhibitors will be taught by guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.
PMNM12 Research Innovation and Management

The growth of the personalised medicine industry and advances within medicine and engineering that have led to the emergence of nanomedicine, present exciting opportunities for the development of advanced therapeutics. However, the management of research and innovation from discovery through to the transition to clinical trial, present unique project management, regulatory and ethical challenges that must be considered to effectively develop new diagnostics and therapeutics. This module will take students through the development process for a novel nanomedicine, highlighting the project management, ethical and regulatory considerations at each stage. The module will also explore the challenges faced from an academic and industry perspective, as well as providing the opportunity for students to learn from industry leaders with direct experience of the research and innovation journey.

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Miss Samantha Thomas

Telephone number

Email address

Welsh language proficiency

About

Areas Of Expertise

Career Highlights

Taught Modules

PMNM11 Nanomedicines, pharmaceuticals and advanced therapeutics

PMNM12 Research Innovation and Management