Dr Sze Chim Lee

Research Highlights

1. Beer-Hammer, S., Lee, S., Mauriac, S., Leiss, V., Groh, I., Novakovic, A., Piekorz, R., Bucher, K., Chen, C., Ni, K., Singer, W., Harasztosi, C., Schimmang, T., Zimmermann, U., Pfeffer, K., Birnbaumer, L., Forge, A., Montcouquiol, M., Knipper, M...., & Lee, S. (2018). Gα_i Proteins are Indispensable for Hearing. Cellular Physiology and Biochemistry, 1509-1532.

   https://doi.org/10.1159/000490867, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40822

   https://www.karger.com/Article/FullText/490867
2. John, A., McGregor, J., Jones, I., Lee, S., Walters, J., Owen, M., O'Donovan, M., DelPozo-Banos, M., Berridge, D., Lloyd, K., & Lee, S. (2018). Premature mortality among people with severe mental illness — New evidence from linked primary care data. Schizophrenia Research, 199, 154-162.

   https://doi.org/10.1016/j.schres.2018.04.009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39476
3. Wilke, T., Mueller, S., Lee, S., Majer, I., Heisen, M., & Lee, S. (2017). Drug survival of second biological DMARD therapy in patients with rheumatoid arthritis: a retrospective non-interventional cohort analysis. BMC Musculoskeletal Disorders, 18(1)

   https://doi.org/10.1186/s12891-017-1684-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38116
4. Mauriac, S., Hien, Y., Bird, J., Carvalho, S., Peyroutou, R., Lee, S., Moreau, M., Blanc, J., Geyser, A., Medina, C., Thoumine, O., Beer-Hammer, S., Friedman, T., Rüttiger, L., Forge, A., Nürnberg, B., Sans, N., Montcouquiol, M., & Lee, S. (2017). Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome. Nature Communications, 8, 14907

   https://doi.org/10.1038/ncomms14907, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38115
5. Möhrle, D., Ni, K., Varakina, K., Bing, D., Lee, S., Zimmermann, U., Knipper, M., Rüttiger, L., & Lee, S. (2016). Loss of auditory sensitivity from inner hair cell synaptopathy can be centrally compensated in the young but not old brain. Neurobiology of Aging, 44, 173-184.

   https://doi.org/10.1016/j.neurobiolaging.2016.05.001, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38113
6. Chumak, T., Rüttiger, L., Lee, S., Campanelli, D., Zuccotti, A., Singer, W., Popelář, J., Gutsche, K., Geisler, H., Schraven, S., Jaumann, M., Panford-Walsh, R., Hu, J., Schimmang, T., Zimmermann, U., Syka, J., Knipper, M., & Lee, S. (2015). BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury. Molecular Neurobiology, 53(8), 5607-5627.

   https://doi.org/10.1007/s12035-015-9474-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38114
7. Bing, D., Lee, S., Campanelli, D., Xiong, H., Matsumoto, M., Panford-Walsh, R., Wolpert, S., Praetorius, M., Zimmermann, U., Chu, H., Knipper, M., Rüttiger, L., Singer, W., & Lee, S. (2015). Cochlear NMDA Receptors as a Therapeutic Target of Noise-Induced Tinnitus. Cellular Physiology and Biochemistry, 35(5), 1905-1923.

   https://doi.org/10.1159/000374000, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38112
8. Dettling, J., Franz, C., Zimmermann, U., Lee, S., Bress, A., Brandt, N., Feil, R., Pfister, M., Engel, J., Flamant, F., Rüttiger, L., Knipper, M., & Lee, S. (2013). Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells. Molecular and Cellular Endocrinology, 382(1), 26-37.

   https://doi.org/10.1016/j.mce.2013.08.025, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38111
9. Zuccotti, A., Lee, S., Campanelli, D., Singer, W., Satheesh, S., Patriarchi, T., Geisler, H., Köpschall, I., Rohbock, K., Nothwang, H., Hu, J., Hell, J., Schimmang, T., Rüttiger, L., Knipper, M., & Lee, S. (2013). L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2-mediated control of cochlear BDNF expression. Frontiers in Molecular Neuroscience, 6

   https://doi.org/10.3389/fnmol.2013.00020, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38108
10. Rüttiger, L., Singer, W., Panford-Walsh, R., Matsumoto, M., Lee, S., Zuccotti, A., Zimmermann, U., Jaumann, M., Rohbock, K., Xiong, H., Knipper, M., & Lee, S. (2013). The Reduced Cochlear Output and the Failure to Adapt the Central Auditory Response Causes Tinnitus in Noise Exposed Rats. PLoS ONE, 8(3), e57247

    https://doi.org/10.1371/journal.pone.0057247, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38110
11. Singer, W., Zuccotti, A., Jaumann, M., Lee, S., Panford-Walsh, R., Xiong, H., Zimmermann, U., Franz, C., Geisler, H., Köpschall, I., Rohbock, K., Varakina, K., Verpoorten, S., Reinbothe, T., Schimmang, T., Rüttiger, L., Knipper, M., & Lee, S. (2012). Noise-Induced Inner Hair Cell Ribbon Loss Disturbs Central Arc Mobilization: A Novel Molecular Paradigm for Understanding Tinnitus. Molecular Neurobiology, 47(1), 261-279.

    https://doi.org/10.1007/s12035-012-8372-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38109
12. Rees, S., Akbari, A., Collins, H., Lee, S., Marchant, A., Rees, A., Thayer, D., Wang, T., Wood, S., & John, A. (2019). Developing a standardised approach to the aggregation of inpatient episodes into person-based spells in all specialties and psychiatric specialties. BMC Medical Informatics and Decision Making, 19(1)

    https://doi.org/10.1186/s12911-019-0953-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53019
13. Lee, S., del Pozo Banos, M., Lloyd, K., Jones, I., Walters, J., Owen, M., O'Donovan, M., & John, A. (2020). Area deprivation, urbanicity, severe mental illness and social drift — A population-based linkage study using routinely collected primary and secondary care data. Schizophrenia Research, 220, 130-140.

    https://doi.org/10.1016/j.schres.2020.03.044, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53852
14. Kendall, K., John, A., Lee, S., Rees, E., Pardiñas, A., del Pozo Banos, M., Owen, M., O'Donovan, M., Kirov, G., Lloyd, K., Jones, I., Legge, S., & Walters, J. (2020). Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: data-linkage study. BJPsych Open, 6(6)

    https://doi.org/10.1192/bjo.2020.42, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55778

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