Dr Wendy Francis

Research Highlights

1. Francis, W., Ireland, R., Spear, A., Jenner, D., Watts, S., Kirkman, E., Pallister, I. 2019 Flow Cytometric Analysis of Hematopoietic Populations in Rat Bone Marrow. Impact of Trauma and Hemorrhagic Shock Cytometry Part A 95 11 1167 1177

   https://cronfa.swan.ac.uk/Record/cronfa51993 doi: 10.1002/cyto.a.23903
2. Jessop, Z., Al-Sabah, A., Francis, W., Whitaker, I. 2016 Transforming healthcare through regenerative medicine BMC Medicine 14 1

   https://cronfa.swan.ac.uk/Record/cronfa29742 doi: 10.1186/s12916-016-0669-4
3. Francis, W., Bodger, O., Pallister, I. 2012 Altered leucocyte progenitor profile in human bone marrow from patients with major trauma during the recovery phase. Br J Surg 99 11 1591 1599

   https://cronfa.swan.ac.uk/Record/cronfa13008 doi: 10.1002/bjs.8919
4. Tu, Y., Xue, H., Francis, W., Davies, A., Pallister, I., Kanamarlapudi, V., Xia, Z. 2013 Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3 Biochemical and Biophysical Research Communications 441 1 249 255

   https://cronfa.swan.ac.uk/Record/cronfa16395 doi: 10.1016/j.bbrc.2013.10.047
5. Naderi, N., Wilde, C., Haque, T., Francis, W., Seifalian, A., Thornton, C., Xia, Z., Whitaker, I. 2014 Adipogenic differentiation of adipose-derived stem cells in 3-dimensional spheroid cultures (microtissue): Implications for the reconstructive surgeon Journal of Plastic, Reconstructive & Aesthetic Surgery 67 12 1726 1734

   https://cronfa.swan.ac.uk/Record/cronfa18931 doi: 10.1016/j.bjps.2014.08.013
6. Xia, Z., Francis, W., Kanamarlapudi, V., Owens, S. 2014 The temporal expression of estrogen receptor alpha-36 and runx2 in human bone marrow derived mesenchymal stromal cells during osteogenesis Biochem Biophys Res Commun

   https://cronfa.swan.ac.uk/Record/cronfa19126 doi: 10.1016/j.bbrc.2014.09.111

   http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=25281901
7. Day, A., Francis, W., Fu, K., Pieper, I., Guy, O., Xia, Z., Guy, O., Francis, W., Xia, Z. 2018 Osteogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells on Coralline Hydroxyapatite/Calcium Carbonate Microparticles Stem Cells International 2018 1 9

   https://cronfa.swan.ac.uk/Record/cronfa46128 doi: 10.1155/2018/4258613

All Research

• PM-120 Skills for Geneticists I

  This module is designed to develop the skills required for students of genetics and medical genetics. Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.

• PM-132 Eukaryotic Cell Biology

  This module will provide a broad introduction to fundamental concepts in Eukaryotic cell biology investigating the origins of the cell, cell structure and specialised cells and cells in disease. There will be a general focus on human cells throughout with reference to other organisms when needed. Students will gain practical experience in identification, differentiation of cells from different human and animal species.

• PM-132C Bioleg Celloedd Ewcaryotig

  Bydd y modiwl hwn yn darparu cyflwyniad bras i gysyniadau sylfaenol ym maes bioleg celloedd Ewcaryotig, gan ymchwilio i darddiad y gell, strwythur y gell a chelloedd arbenigol a chelloedd mewn clefyd. Bydd ffocws cyffredinol ar gelloedd dynol drwy gydol y modiwl, gan gyfeirio at organebau eraill yn ôl yr angen. Bydd myfyrwyr yn cael profiad ymarferol o nodi celloedd, gwahaniaethu rhwng gwahanol gelloedd dynol a rhywogaethau o anifeiliaid.

• PM-200 Skills For Geneticists II

  This module will give assignments designed to build on essay writing and oral presentation skills introduced in level 1. It will also develop critical evaluation, analysis skills for the understanding of peer-reviewed research papers.

• PM-246 Biochemistry Skills Development II

  This module is designed to develop the skills required for students of biochemistry. Students meet with tutors and will be given a series of assignments designed to develop skills in key areas including essay writing, presentation and analysis of research papers.

• PM-344 Capstone Project

  The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project. Depending on the student's employability strand within the programme, the project may be laboratory, data, or education-based, but it will always involve a research question that is drawn from the literature, focused on a topic relevant to medical science. It will ask a novel research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through creating an introductory presentation on the project background, and a written dissertation and oral presentation on their research conclusions.

• PM-347 Human Immunopathology

  The module aims to provide students with a greater understanding of the human immune system and the causes of a range of diseases associated with immune dysfunction including autoimmune diseases, metabolic disorders and neurological conditions.

• PM-358 Tissue Engineering and Regenerative Medicine

  This module will provide students with a firm understanding of the principles of Regenerative Medicine that extend from cellular to tissue and organ repair and regeneration. This module will focus on the practical aspects of revolutionary technologies, generated through research, that have the potential to significantly improve how we treat injury, illness and disease.

• PMGM11 Introduction to Human Genetics and Genomics

  The Introduction to Human Genetics and Genomics module is a subject-specific module in the MSc Genomic Medicine programme. This unit will provide essential and contemporary knowledge relating to genetic science and genetic disease. The module will prepare participants to understand disease genetics, how genomic medicine can be utilised to elucidate disease mechanisms and biology in the context of genomic medicine. It will provide core knowledge underpinning later modules in bioinformatics and statistics. This module will serve as a foundation for those wishing to advance their careers within the NHS in genomic medicine.

• PMGM18 Critical Literature Review

  This module will allow students to carry out a critical and in-depth evaluation of previous research based on a specific subject related to genomics