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PM-120
Skills for Geneticists I
This module is designed to develop the skills required for students of genetics and medical genetics.
Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy.
Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.
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PM-240
Carbohydrate Metabolism and Glycobiology
Saccharides are the major source of energy and carbon that is used by the cell for growth and maintenance. The central roles of glycolysis in providing cellular energy and components from saccharides substrates, and the regulation of these processes are explained. The relationship between glycolysis and glycogen metabolism in mammals is explored as one of the ways in which substrate supply to the pathway is regulated. The complexity of the mechanisms, including hormonal, for controlling glycolysis and gluconeogenesis in mammalian to maintain blood concentrations is compared to glycogen and glucose metabolism in muscle tissue. The role or glycosyltransferases in the synthesis of oligo- and polysaccharides, including glycoprotein assembly, is also explained.
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PM-273
Advances in Toxicology: Pick Your Poison
BSc Medical Pharmacology module, follow on from PM-147 Introduction to Toxicology.
This module will provide students with the opportunity to expand their toxicology knowledge and apply it to analytical experience. This module will encompass medical toxicology, applied toxicology, and clinical poison information.
Content will be analytical, forensic and clinical toxicology.
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PM-300
Medical Genetics
The course is designed to provide an advanced study of the identification of human genes and the determination of the influence of human genes upon disease and health status. Gene identification provides targets for the development of new pharmaceuticals and the range of variation present in the population.
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PM-304
Biomolecular Research Project
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PM-334
Biochemistry Literature Review and Communication
Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.
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PM-334C
Adolygiad Llenyddiaeth Biocemeg a Chyfathrebu
Bydd y myfyrwyr yn dysgu gwybodaeth fanwl o un maes ymchwil cyfamserol â phwysigrwydd allweddol i'w cynllun gradd penodol.
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PM-357
Biomedical Laboratory Techniques
The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.
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PM-357C
Technegau Labordy Biofeddygol
Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.
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PM-400
Advanced Research Project A
The advanced research project is a key component of the final year of study, providing students with experience of
conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an 9-month period.
The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and
Immunity; Devices. Students will employ a range of advanced analytical procedures to investigate a specific topic.
In addition, they will gain experience in preparing a research proposal and presenting their data in various formats.
Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student
could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique
of RNA interference.
The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-400
includes the following components: (1) Preparation of a research poster, (2) A 15-minute audio recording giving a presentation of the research area, (3) Lab performance and (4) Oral defence of the project in an open viva (20-minute presentation followed
by 10-minutes of questions).
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PM-400C
Prosiect Ymchwil Uwch A
Mae'r prosiect ymchwil uwch yn elfen allweddol o'r flwyddyn astudio olaf. Mae'n rhoi cyfle i fyfyrwyr gael profiad o ymgymryd ag ymchwil arloesol yn y Sefydliad Gwyddor Bywyd a'r Ganolfan NanoIechyd am naw mis. Bydd y prosiect yn canolbwyntio ar un o'r themâu ymchwil canlynol sy'n berthnasol i'r gwyddorau meddygol: Biofarcwyr a Genynnau; Microbau ac Imiwnedd; Dyfeisiau. Bydd myfyrwyr yn defnyddio amrywiaeth o dechnegau dadansoddi uwch i ymchwilio i bwnc penodol. Yn ogystal, byddant yn cael profiad o lunio cynnig ymchwil a chyflwyno eu data mewn amrywiaeth o fformatau. Dynodir themâu ymchwil sy'n briodol i deitl gradd penodol. Er enghraifft, os yw myfyriwr yn astudio Geneteg, gellir dynodi prosiect yn ymchwilio i weithrediad gennyn mewn fector pryfed clefyd trofannol, gan ddefnyddio techneg ymyrraeth RNA.
Rhennir y prosiect ymchwil uwch rhwng dau fodiwl, PM-400 a PM-402. Mae PM-400 yn cynnwys y cydrannau canlynol:
(1) Llunio poster ymchwil;
(2) Recordiad sain 15 munud sy'n cyflwyno'r maes ymchwil;
(3) Perfformiad yn y labordy a
(4) Amddiffyn y prosiect mewn arholiad llafar agored (cyflwyniad 20 munud i'w ddilyn gan 10 munud o gwestiynau).
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PMLM01
Analytical Techniques for Medicinal Chemistry and Nanomedicine
This module will enable students to understand the basic and advanced concepts of separation science, how it is integrated with several forms of compound detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to compound chemical characteristics and method application.
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PMND00
Nanomedicine Research Dissertation
This module builds on the knowledge and skills developed in teaching components in part one of their relevant
programme. Students will work independently in order to critically explore and add to the evidence base for a topic
of relevance to their area of study within nanomedicine.
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PMNM04
Nanomedicines and Therapeutics
The module will explore the history and development of molecular medicines. Using landmark technology and chemical development phases, the traditional small chemical entities using in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. The common target oncology and non oncology disorders will outlined and their respective targets for such medicines detailed alongside drug modes of action and delivery (IV and oral). Further exploration of targeted nanoparticle delivery, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems, will expand the knowledge to future molecular medicines such as antibody drug conjugates and kinase inhibitors. Excitingly the module will include guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.
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PMNM11
Nanomedicines, pharmaceuticals and advanced therapeutics
This module will explore the history and development of molecular medicines and pharmaceuticals, providing the basis for an advanced understanding of next generation therapeutic approaches. Using landmark technology and chemical development phases informed by separation science and mass spectrometry, the module uses an application driven approach to provide the student with an extensive knowledgebase of drug development, the pharmaceutical industry and nanotherapeutics.
Students will be able to characterize and map the path of a drug from administration, to metabolism and elimination, and critically evaluate drug design and delivery approaches. Traditional small chemical entities used in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. Common target oncology and non-oncology disorders will provide the context; with students encouraged to explore targeted nanoparticle fabrication, drug encapsulation and release profiling, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems. Future molecular medicines such as antibody drug conjugates and kinase inhibitors will be taught by guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.
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PMNMD0
Postgraduate Taught Masters Dissertation
Students will have the opportunity to join an established research group or industry partner to work in a modern and well equipped laboratory, or alternatively undertake a suitable non-laboratory based project. In this module the student will be able to gain extensive `hands on¿ specialist expertise in a chosen topic which could be targeted to their future career in the field of nanomedicine/ mass-spectrometry.
Please note that the topic choice will be made in conjunction with the supervisor, based upon novelty, feasibility and practical considerations on a 'first come first served' basis. The final approval of the topic rests with the module lead .
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PMZM15
Nanomedicines and Therapeutics
The module will explore the history and development of molecular medicines. Using landmark technology and chemical development phases, the traditional small chemical entities using in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. The common target oncology and non oncology disorders will outlined and their respective targets for such medicines detailed alongside drug modes of action and delivery (IV and oral). Further exploration of targeted nanoparticle delivery, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems, will expand the knowledge to future molecular medicines such as antibody drug conjugates and kinase inhibitors. Excitingly the module will include guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.
