Dr Angelini’s main scientific interest is the relationship between lipid chemical structures and their biological function. He routinely employs mass spectrometry to carry out lipidomics studies as applied to biomedical research. He is confident that by studying lipid biological function we can increase our understanding of the fundamental mechanisms of several diseases.
Dr Angelini received his Master’s Degree and Ph.D. at the University of Bari in the laboratory of Angela Corcelli where he was trained on deciphering the lipid composition of biomembranes of archaeal, bacterial and eukaryotic cells, exposed to different environmental modifications including osmotic stress, oxygen availability, and exposure to pharmacologically active compounds. At the Corcelli Lab, he developed analytical tools based on lipid profiling for biomedical research and clinical applications. Later, he sharpened his knowledge and technical skills in mass spectrometry in the laboratories of Valerian Kagan at Pittsburgh University and of Daniele Piomelli at the University of California, Irvine.
He returned to Europe with an MSCA-COFUND Fellowship to work in the Griffiths-Wang laboratory at Swansea University where he developed mass spectrometry applications to image sterols in the brain. Here he also took his first faculty position at the Swansea University Medical School in the Institute of Life Science as Lecturer (Enhanced Research).