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Ernest’s research addresses direct clinical need. His research is patient-oriented, demand-driven and clinically applicable. His interests are cutaneous laser surgery and soft tissue infection. His collaborations wth strategic regional partners including clinical surgery, microbiology, histopathology, and further afield in Milan and Malta have yielded key outputs including publications cited in policy documents, and IP. More importantly, his work has helped make patients better faster, through directly impacting clinical care in a number of areas. After completing basic surgical training and an MSc in Surgery within the Wales and Oxford Deaneries, Dr Azzopardi completed his specialist training in plastic surgery within Wales, followed by entry on the UK specialist register. He furthered his special interest in laser through competitively securing a Training Interface Group fellowship in therapeutic use of laser, under the mentorship of Mr Maxwell Murison followed by a super-specialist fellowship in laser and photonics under the mentorship of Dr M. Tretti in Milan, both world-leading authorities in the field. 

After his PhD was conferred, without corrections, from Cardiff University UK, Ernest proceeded to become an accomplished researcher and developing key opinion leadership in his chosen field, publishing in established journals such as the Lancet, JPRAS, and PRS, and others. He has been fortunate in having his work recognised through several awards including the BAAPS travelling fellowship, the Royal College of Surgeons in England 2015 Hunterian Professor & Medal, the Royal College of Surgeons in Edinburgh 2014 James Syme Medal, the BAPRAS president’s medal (2014), the British Burns Association’s Jackson Award (2012), the ABAOMS Prize (2012), the Unilever poster prize (2011-12) among others. More recently he has been awarded the Gieh il-Qrendi civic award, for services to medical research from Malta (EU). Dr Azzopardi’s funding mix includes charities, regional, UK, EU/ESF, and international research grants. This background informs his clinical practice with a depth of knowledge, and grounds it in current best evidence. His works are cited in Policy by the US dept of Department of Defence and the USA Military among others. He continues to review for the British Journal of Surgery, the Journal of Antimicrobial Chemotherapy and the Journal of Plastic Reconstructive Surgery. He is an Editorial Board Member of Scientific Reports (Nature Publishing Group). His research ethos is inclusive and interdisciplinary. Dr Azzopardi firmly believes in the principle of teaching as nurturing the next generation of leaders in the field.

Areas of Expertise

  • Laser and Reconstruction
  • Plastic Reconstructive and Burn Surgery
  • Nanomedicine (polymer therapeutics)
  • Drug Discovery
  • Translational research
  • Mathematics in Experimental Medicine


  1. McGoldrick, R., Theodorakopoulou, E., Azzopardi, E., Murison, M. Lasers and ancillary treatments for scar management Part 2: Keloid, hypertrophic, pigmented and acne scars Scars, Burns & Healing 3 205951311668980
  2. Marsden, N., Van, M., Dean, S., Azzopardi, E., Hemington-Gorse, S., Evans, P., Whitaker, I. Measuring coagulation in burns: an evidence-based systematic review Scars, Burns & Healing 3 205951311772820
  3. Azzopardi, E., Ferguson, E., Thomas, D. Development and Validation of anIn VitroPharmacokinetic/Pharmacodynamic Model To Test the Antibacterial Efficacy of Antibiotic Polymer Conjugates Antimicrobial Agents and Chemotherapy 59 4 1837 1843
  4. Azzopardi, E. Royal College of Surgeons in England 2015 Hunterian Professor
  5. Azzopardi, E. Finalist, Academy of Medical Sciences Young Scientist Award. Royal College of Physicians Academy of Medical Sciences 2014 Young Investigator Award

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  • PMNM04 Nanomedicines and Therapeutics

    The module will explore the history and development of molecular medicines. Using landmark technology and chemical development phases, the traditional small chemical entities using in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. The common target oncology and non oncology disorders will outlined and their respective targets for such medicines detailed alongside drug modes of action and delivery (IV and oral). Further exploration of targeted nanoparticle delivery, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems, will expand the knowledge to future molecular medicines such as antibody drug conjugates and kinase inhibitors. Excitingly the module will include guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.


  • Graphene-based amylase biosensor for infection diagnosis (awarded 2020)

    Other supervisor: Prof Steve Conlan