Claire gained her PhD in 2002 and since then has worked in the field of cancer research. Claire has previously held a post at the prestigious MRC Cancer Cell Unit in Cambridge before returning to Swansea University. Claire is based at the Institute of Life Science 1 where her research focuses on cancer drug discovery and gene manipulation. She has recently been awarded Cancer Research UK and Welsh Government Funding to further her drug discovery research.

Claire is a Senior Lecturer in Genetics and teaches on the Genetics/ Medical Genetics/Applied Medical Sciences BSc degree schemes and Graduate Entry Medicine in the School of Medicine. She has been Chair of the Student Staff Committee for the past 5 years and sits on the Genetics and Biochemistry board of studies, Applied Medical Sciences Board of Studies and College Learning and Teaching Committee.

She is a senior fellow of the Higher Education Academy (HEA) and an external reviewer for the HEA. Most recently Claire, as programme director, has established the first fully NHS- supported Genomic Medicine course in Wales.

Areas of expertise include:

  • Medical Genetics
  • Cancer research
  • Angiogenesis
  • Cancer drug discovery

Administrative responsibilities

  • Programme Director – MSc Genomic Medicine
  • Msci – co-ordinator Genetics and Biochemistry
  • Chair – School of Medicine Student Staff Consultative Committee
  • Member – School of Medicine Learning and Teaching Committee
  • Member – School of Medicine Genetics and Biochemistry Board of Studies
  • Member – School of Medicine Applied Medical Sciences
  • Member - School of Medicine Research Committee
  • Member – Post-graduate Taught Committee

External responsibilities

  • Grant reviewer for CRUK
  • External reviewer for HEA
  • Senior Fellow of the HEA
  • University representative for the Biology Education Research Group
  • Local representative for Genetics society

Publications

  1. Morgan, C, Jenkins, G, Ashton, T, Griffiths, A, Baxter, J, Parry, E, Parry, J Detection of p53 mutations in precancerous gastric tissueBritish Journal of Cancer89713141319
  2. Dunstan, P, Doak, S, Morgan, C, Walker, K, Schnur, J Quantum Dots for Multiplexed Detection and Characterisation of Prostate Cancer Cells Using a Scanning Near-Field Optical MicroscopePLoS ONE72e31592
  3. Dudley, E, Nigam, Y, Ratcliffe, N, Newton, R, Wagstaff, J, Morgan, C, Bond, A, Bexfield, A Amino acid derivatives fromLucilia sericataexcretions/secretions may contribute to the beneficial effects of maggot therapy via increased angiogenesisBritish Journal of Dermatology1623554562
  4. Morgan, C, Jeremiah, S, Wagstaff, J Ibandronate reduces endogenous reactive oxygen species levels in cultured prostate cancer and endothelial cellsMicrovascular Research782141141
  5. Wagstaff, J, Jeremiah, S, Morgan, C Metronomic administration of ibandronate and its anti-angiogenic effects in vitroMicrovascular Research78453458

See more...

Teaching

  • PM-149 Fundamental Genetics and Evolution

    The module will provide a foundation in genetics and evolution. Concepts such as DNA discovery, structure and replication, gene transcription and translation, mechanisms of gene transmission, genome organisation, epigenetic modifications and mutations will be covered with an appreciation of how how these mechanisms have an impact on human disease and antibiotic resistance. The latter part of the module will start with the work of Plato, Cuvier, Lamarck, Wallace and Darwin and how they (and others) influenced the development of an evolutionary theory framework. Using this knowledge the module will then look at the processes involved in speciation and how they can be applied at both the gene and whole organismal level.

  • PM-267 Genes on Drugs: Pharmacogenomics

    Genes affect how the body reacts to drugs as well as how they are absorbed, metabolized and eliminated. You will learn how variation in genes encoding proteins involved in these processes affect how drugs work ¿ or don¿t ¿ therapeutically. By understanding these factors, you will gain insight into the emerging field of personalized medicine and learn how individualized drug design and selection can improve therapeutic efficacy, safety and sustainability.

  • PM-317 Genetics of Cancer

    This module will provide students with an advanced understanding about the genetic mechanisms involved in carcinogenesis, and how these underlying processes and molecules affect the human body.

  • PM-338 Teaching Science In Schools

    This module is for students with an interest in entering teaching, and involves placements in local schools The student will engage both in observation and in various teaching activities. The module will be assessed through various methods including a written report and the teachers report.

  • PM-342 Advances in Pharmacology

    Pharmacology is the science of how drugs act on the body and how the body acts on drugs. Pharmacology investigates the chemical and physical properties of drugs, how those properties confer actions on living tissues and how those actions affect health and disease. The beneficial, therapeutic effects of drugs will be discussed, but also some negative consequences of drug administration, such as toxicity, addiction and microbial drug-resistance.

  • PM-354 Cancer Pharmacology

    Cancer remains a significant cause of mortality in the modern world. Current and emerging chemotherapies, and the rationale, experimental, and clinical evidence of the pathways or molecules targeted will be explored. Causes of treatment-related side effects, and the therapies used to address these, will be discussed along with the mechanisms that lead to anti-cancer drug resistance.

  • PM-402 Advanced Research Project B

    The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an 9-month period. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-402 comprises the final written dissertation.

  • PMGM13 Ethical, Legal and Societal Issues (ELSI) in Applied Genomics

    This module will provide students with an understanding of the legal, regulatory & governance frameworks associated with medical genomics and the use of genomic data. It will equip students to explore and evaluate the main ethical, legal and social issues (ELSI) involved in: genomic testing and the wider implications for the patient and their families; precision medicine; and the use of genomic data for population research.

  • PMGM16 Genomics of Common and Rare Inherited Disease

    This module will provide an introduction to the clinical presentation and manifestations of rare inherited and common diseases, and considers the patient and family perspective with respect to the role and impact of genomics. It reviews traditional and current strategies and techniques used to identify genes responsible for both common multifactorial and rare inherited diseases.

  • PMGM17 Research Dissertation

    The module is for students to build on their previous knowledge, skills and experience by undertaking a medical genomics research project.

  • PMGM18 Critical Literature Review

    This module will allow students to carry out a critical and in-depth evaluation of previous research based on a specific subject related to genomics

Supervision

  • Pre-operative assessment of invasive lobular carcinoma of the breast - comparing Digital Breast Tomosynthesis with C-view, and magnetic resonance imaging. (current)

    Student name:
    MD
    Other supervisor: Dr Claire Morgan
    Other supervisor: Prof Paul Lewis
  • Bacterial Targeting and Manipulation of Tumour Cell Metabolism (current)

    Student name:
    PhD
    Other supervisor: Dr Claire Morgan
    Other supervisor: Prof Paul Dyson
  • “DEVELOPING BACTERIAL MEDIATED RNAi AS A THERAPY FOR PANCREATIC CANCER” (awarded 2019)

    Student name:
    MSc
    Other supervisor: Dr Claire Morgan
    Other supervisor: Prof Paul Dyson
  • Investigation of the utility of optical spectroscopy for management of chronic respiratory disease through investigation of sputum mucin glycosylation patterns (awarded 2019)

    Student name:
    PhD
    Other supervisor: Dr Claire Morgan
    Other supervisor: Prof Paul Lewis
  • The anti-cancer potentials of LSer-Cec5 and Temporin A on non-small cell lung cancer. (awarded 2019)

    Student name:
    MSc
    Other supervisor: Prof Paul Lewis
    Other supervisor: Dr Claire Morgan
  • 'Unbiased and targeted metabolomic approaches to biomarker discovery for pancreatic cancer' (awarded 2018)

    Student name:
    MSc
    Other supervisor: Dr Claire Morgan
    Other supervisor: Dr Ed Dudley
  • 'The role of STEAP2 in Prostate Cancer Progression' (awarded 2017)

    Student name:
    PhD
    Other supervisor: Dr Claire Morgan
    Other supervisor: Prof Shareen Doak

Administrative Responsibilities

  • Programme Director – MSc Genomic Medicine - Swansea University Medical School

    2018 - Present

  • Member - Post-graduate Taught Committee - Swansea University Medical School

    2017 - Present

  • Co-ordinator - MSci Biochemistry and Genetics - Swansea University Medical School

    2016 - Present

  • Member - Applied Medical Sciences Board of Studie - Swansea University Medical School

    2015 - Present

  • Member - Research Committee - Swansea University Medical School

    2014 - Present

  • Member - Athena Swansea Communication and Culture Working Group - Swansea University Medical School

    2014 - Present

  • Member - Biochemistry and Genetics Board of Studies

    2011 - Present

  • Member - Learning and Teaching Committee - Swansea University Medical School

    2011 - Present

  • Chair - Medical School Student Staff Consultative Committee - Swansea University Medical School

    2011 - 2017