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This module is designed to develop the skills required for students of genetics and medical genetics. Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.
This module is designed to develop the skills required for students of biochemistry and medical biochemistry. Students meet with their tutors and will be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint session cover generic skills such as internet searching for scientific sources, referencing and plagiarism
The module starts with a consideration of aspects of genetics and related topics, eg. mitosis and meiosis, mutation, genomes, recombination, transcription, translation, protein structure and protein properties. The second part of the module deals with evolutionary biology, natural selection and variation, molecular evolution, species and their creation, classification and phylogeny.
This module will provide a broad introduction to fundamental concepts in microbiology (bacteria and viruses). Students will gain practical experience in handling and culturing microorganisms, microscopy and staining techniques.
The control systems governing gene expression in prokaryotic cells are explored and the molecular basis for gene regulation introduced. Practical skills in obtaining and analysing data on a bacterial system are developed. The module then assesses the structure of the bacterial genome and how genetic analysis can be used to investigate structure and function of individual components of that genome. Specific examples explored in depth are the genetics of recombination and DNA repair. The technologies used for functional genomic analysis of fully sequenced bacteria are described with reference to analysis of human pathogens. Finally, the module includes examples of synthetic biology applied to bacteria.
The module will provide a sound theoretical and practical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, transcriptomics, proteomics and mass spectrometry.
Bydd y modiwl yn darparu sylfaen ddamcaniaethol ac ymarferol gref ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, transgriptomeg, proteomeg a sbectrometreg màs.
The module aims to explain the biological basis of biotechnology and protein engineering: their limitations, industrial and medical importance. Students will develop their skills in gathering and interpreting relevant information.
The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an 9-month period. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-402 comprises the final written dissertation.