Dr Nigel Francis is a lecturer on our Biochemistry Degrees.
Dr Nigel Francis is a lecturer on our Biochemistry Degrees.
The module will provide the student with a broad overview of dietary requirements, digestion processes and associated anatomy, nutrient uptake and energetic metabolism processes within the human body. The catabolism of biomolecules for energy production will be covered and the role of the kidney in removal of by-products. The role of neuronal and hormonal systems in homeostatic control of the body will also be elaborated.
The module will provide the student with a diversity of laboratory and scientific skills in relation to the undertaking of undergraduate practical sessions in a safe manner and develop skills including molarity calculations, biological extractions, basic chromatography, an introduction into anatomical dissection and physiology.
This module begins with an introduction to enzymology, enzyme kinetics and enzyme regulation. Next there is an introduction to bioenergetics and a discussion of the central metabolic pathways by which energy from food is used to fuel the synthesis of the energy currency molecule ATP (with particular attention to glycolysis, the citric acid cycle, ß oxidation of fatty acids, and oxidative phosphorylation). The concept of tissue and organ specificity is introduced, and finally the role of the hormones insulin, glucagon, epinephrine, growth hormone, thyroid hormone and leptin in controlling these pathways and producing effects on the body is considered.
This module is designed to develop the skills required for students of biochemistry and medical biochemistry. Students meet with their tutors and will be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint session cover generic skills such as internet searching for scientific sources, referencing and plagiarism
The module provides a broad study of the interactions between chemical processes and biological systems. It addresses the chemical processes used by organisms to utilize chemicals for energy production, structural functions and as building blocks of macromolecules.
This module will provide a broad introduction to fundamental concepts in Eukaryotic cell biology investigating the origins of the cell, cell structure and specialised cells and cells in disease. There will be a general focus on human cells throughout with reference to other organisms when needed. Students will gain practical experience in identification, differentiation of cells from different human and animal species.
Bydd y modiwl hwn yn darparu cyflwyniad bras i gysyniadau sylfaenol ym maes bioleg celloedd Ewcaryotig, gan ymchwilio i darddiad y gell, strwythur y gell a chelloedd arbenigol a chelloedd mewn clefyd. Bydd ffocws cyffredinol ar gelloedd dynol drwy gydol y modiwl, gan gyfeirio at organebau eraill yn ôl yr angen. Bydd myfyrwyr yn cael profiad ymarferol o nodi celloedd, gwahaniaethu rhwng gwahanol gelloedd dynol a rhywogaethau o anifeiliaid.
The module starts with a consideration of aspects of genetics and related topics, eg. mitosis and meiosis, mutation, genomes, recombination, transcription, translation, protein structure and protein properties. The second part of the module deals with evolutionary biology, natural selection and variation, molecular evolution, species and their creation, classification and phylogeny.
The module begins with a discussion of selected metabolic disorders of carbohydrate metabolism and their pathological consequences with particular emphasis on diabetes mellitus. The molecular mechanisms underlying polycystic ovarian syndrome are then considered. This is followed by a consideration of the biochemical basis of haemostasis and blood clot lysis. Next there is a discussion of inborn errors of metabolism, and the biochemical pathways affected. Finally the module reviews mechanisms of protein transport and their relevance to storage diseases.
This module reviews the basic elements of enzyme kinetics, including their mechanism and inhibition. The control of enzyme function by allosteric mechanisms is considered together with an appreciation of the significance of sigmoid kinetics. An overview of coenzymes and (metal) co-factors in enzyme function is given together with a description of the role played by vitamins in co-enzyme production. The module concludes with an overview of enzymes from extremophiles and their applications.
This module is designed to develop the skills required for students of biochemistry. Students meet with tutors and will be given a series of assignments designed to develop skills in key areas including essay writing, presentation and analysis of research papers.
Nod y modiwl hwn yw datblygu'r sgiliau mae eu hangen ar fyfyrwyr biocemeg. Bydd myfyrwyr yn cwrdd â thiwtoriaid ac yn derbyn cyfres o aseiniadau at ddiben datblygu eu sgiliau mewn meysydd allweddol, gan gynnwys ysgrifennu traethodau, cyflwyno a dadansoddi papurau ymchwil.
The course is designed as an introduction to immunology and the human immune system. The course covers the fundamentals of immunology including functional perturbations associated with disease and experimental approaches to the study of immunology.
The module will provide a sound theoretical and practical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, transcriptomics, proteomics and mass spectrometry.
Bydd y modiwl yn darparu sylfaen ddamcaniaethol ac ymarferol gref ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, transgriptomeg, proteomeg a sbectrometreg màs.
Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.
The module aims to provide students with a greater understanding of the human immune system and the causes of a range of diseases associated with immune dysfunction including autoimmune diseases, metabolic disorders and neurological conditions.