I am a British Heart Foundation sponsored research scientist. I'm one of those awkward people who uses their middle name, so most will know me as Lowri. My research focusses on the massice intracellular cardiac ion channel, the ryanodine receptor (RyR2) and its role in health and disease - in particular the generation of cardiac arrhythmia. My role in the Molecular Cardiology Group is to use mutagenesis and expression techniques to make recombinant ion channel proteins and assess their gating behaviour (i.e. the way in which they open and close) using single channel recording in lipid bilayers. I'm also looking at in how these molecular events translate into calcium release dysfunction at the cellular level. As a result, I have an interest in the use of human induced pluripotent stem cell derived cariac myocytes as a model for arrhythmic disease.