Areas of Expertise

  • DSc IWAF FSB FRSC FLSW

Publications

  1. & Loss of C-5 sterol desaturase activity results in increased resistance to azole and echinocandin antifungals in a clinical isolate of Candida parapsilosis. Antimicrobial Agents and Chemotherapy, AAC.00651-17
  2. & Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence. G3 Genes|Genomes|Genetics 6(11)
  3. & The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme. Antimicrobial Agents and Chemotherapy 60(8), 4530-4538.
  4. & Multidrug transporters and alterations in sterol biosynthesis contribute to azole antifungal resistance in Candida parapsilosis.. Antimicrob.Ag.Chemother. 59
  5. & Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa. Scientific Reports 6, 27690

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Supervision

  • Application of GC-MS to the identification of products derived from a couples gasification/Fischer-Tropsch system for the production of hydrocarbons for fuel from carbonaceous waste. (current)

    Student name:
    PhD
    Other supervisor: Dr Ruth Godfrey
    Other supervisor: Prof Steven Kelly