Areas of Expertise

  • DSc IWAF FSB FRSC FLSW

Publications

  1. & Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence. G3 Genes|Genomes|Genetics 6(11)
  2. & The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme. Antimicrobial Agents and Chemotherapy 60(8), 4530-4538.
  3. & Multidrug transporters and alterations in sterol biosynthesis contribute to azole antifungal resistance in Candida parapsilosis.. Antimicrob.Ag.Chemother. 59
  4. & Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa. Scientific Reports 6, 27690
  5. & Analysis of cytochrome b5 reductase-mediated metabolism in the phytopathogenic fungus Zymoseptoria tritici reveals novel functionalities implicated in virulence. Fungal Genetics and Biology

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Supervision

  • Application of GC-MS to the identification of products derived from a couples gasification/Fischer-Tropsch system for the production of hydrocarbons for fuel from carbonaceous waste. (current)

    Student name:
    PhD
    Other supervisor: Dr Ruth Godfrey
    Other supervisor: Prof Steven Kelly
  • 'Exploring the roles of novel secondary metabolites in streptomycetes' (awarded 2014)

    Student name:
    PhD
    Other supervisor: Prof David Lamb
    Other supervisor: Prof Paul Dyson
    Other supervisor: Prof Steven Kelly
  • 'The Role of Cytochrome P450 and ABC Transporters in M. graminicola Antifungal Resistance' (awarded 2013)

    Student name:
    PhD
    Other supervisor: Prof Steven Kelly
    Other supervisor: Prof Diane Kelly
  • Candida CYP52: ALkane and Fatty Acid Metabolism (awarded 2012)

    Student name:
    PhD
    Other supervisor: Prof Steven Kelly
    Other supervisor: Prof Diane Kelly
  • Gene deletion studies in analysis of the role of cytochrome P450 in flaviolin metabolism in Streptomyces coelicolor. (awarded 2009)

    Student name:
    MPhil
    Other supervisor: Prof Steven Kelly
    Other supervisor: Prof David Lamb
  • Development of a Diagnostic Tool for cutaneous Melanoma using Flourescence induced by the Topical Application of 5-Aminolevulanic Acid (awarded 2008)

    Student name:
    PhD
    Other supervisor: Prof Marc Clement
    Other supervisor: Prof Steven Kelly
  • Fungal azole resistance and the role of cytochrome P450 (awarded 2007)

    Student name:
    PhD
    Other supervisor: Prof Steven Kelly
    Other supervisor: Prof Diane Kelly