I have been a member of academic staff in Microbiology and Infectious Disease in the College of Medicine at Swansea University since September 2008 . I undertook my PhD in College of Medicine at Cardiff University (1997-2001) prior to two periods of postdoctoral training in Seattle (Hope Heart Institute, 2001-2004) and Edinburgh (MRC Centre for Inflammation Research, 2004-2008). At Swansea my academic role focuses on basic and translational research, support of postgraduate research degrees and undergraduate teaching.

My research interests include:
1. Development of new anti-biofilm therapeutics to target medical device related infections
2. Identifying innate immune barrier responses in epithelial cells to specific lineages of Campylobacter and Staphylococci
3. Linking bacterial genotype with their phenotypic responses in cell co-culture systems
4. Investigating the interactions between bacterial biofilms in primary leukocyte systems

I can be found in the ILS1 building, in room 137.

Publications

  1. & Limitations in the use of PSMγ, agr , RNAIII, and biofilm formation as biomarkers to define invasive Staphylococcus epidermidis from chronic biomedical device-associated infections. International Journal of Medical Microbiology
  2. et. al. Recombination-Mediated Host Adaptation by Avian Staphylococcus aureus. Genome Biology and Evolution 9(4), 830-842.
  3. & Critical review of the current and future challenges associated with advancedin vitrosystems towards the study of nanoparticle (secondary) genotoxicity. Mutagenesis 32(1), 233-241.
  4. & Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples. PLOS ONE 11(3), e0151240
  5. & Correction: Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples. PLOS ONE 11(4), e0154510

See more...

Teaching

  • PM-132 Eukaryotic Cell Biology

    This module will provide a broad introduction to fundamental concepts in Eukaryotic cell biology investigating the origins of the cell, cell structure and specialised cells and cells in disease. There will be a general focus on human cells throughout with reference to other organisms when needed. Students will gain practical experience in identification, differentiation of cells from different human and animal species.

  • PM-132C Bioleg Celloedd Ewcaryotig

    Bydd y modiwl hwn yn darparu cyflwyniad bras i gysyniadau sylfaenol ym maes bioleg celloedd Ewcaryotig, gan ymchwilio i darddiad y gell, strwythur y gell a chelloedd arbenigol a chelloedd mewn clefyd. Bydd ffocws cyffredinol ar gelloedd dynol drwy gydol y modiwl, gan gyfeirio at organebau eraill yn ôl yr angen. Bydd myfyrwyr yn cael profiad ymarferol o nodi celloedd, gwahaniaethu rhwng gwahanol gelloedd dynol a rhywogaethau o anifeiliaid.

  • PM-249 Human Immunology

    The course is designed as an introduction to immunology and the human immune system. The course covers the fundamentals of immunology including functional perturbations associated with disease and experimental approaches to the study of immunology.

  • PM-250 Infectious Disease and Parasitology

    The course will build on the fundamentals of microbiology and introduce new topics in bacteriology, mycology and parasitology. Level 5 Immunology (PM-249) is a pre-requisite. The course covers the fundamentals of infectious diseases, including clinical aspects, treatment / prevention, and experimental approaches to the study of infectious and parasitic organisms. The course will also cover topics including disease outbreaks, beneficial parasites, tropical disease and behaviour-modifying parasites.

  • PM-304 Biomolecular Research Project

    *

Supervision

  • Defining the mechanisms driving genomic variation and virulence in Helicobacter pylori and identifying the genes/alleles responsible. (current)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Prof Thomas Humphrey
    Other supervisor: Prof Gareth Jenkins
  • Untitled (current)

    Student name:
    PhD
    Other supervisor: Dr Angharad Davies
    Other supervisor: Prof Thomas Humphrey
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Dr Llinos Harris
  • Untitled (current)

    Student name:
    MSc
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Dr Martin Clift
  • Population genomics of bacterial pathogens (current)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Dr Ricardo Del Sol Abascal
  • Population genomics approaches to understanding the evolution and ecology of bacterial pathogens (current)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Dr Ricardo Del Sol Abascal
  • Sensing bacterial infection: 25-hydroxycholesterol as a biomarker (current)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Dr Yuqin Wang
    Other supervisor: Prof Thomas Humphrey
    Other supervisor: Prof William Griffiths
  • Characterization of alginate-mucin glycan interaction for tailored therapeutic development in cystic fibrosis (current)

    Student name:
    PhD
    Other supervisor: Prof Gareth Jenkins
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Prof Paul Lewis
  • Effect of Camplylobacter on the inflammatory response of intestinal cells (current)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Prof Thomas Humphrey