Karl's research interests include the development of advanced rheological techniques for the characterisation of the structure and mechanical properties of biopolymer gelling systems including gelatin, collagen, fibrin and blood.  He is author of over 50 publications in international peer reviewed journals in the fields of fluid mechanics, medical devices and haematology. His research has been funded by EPSRC, NISCHR, British Council, industrial companies and an RCUK fellowship. He is a Co-Investigator of several EPSRC grants (including the current Healthcare Impact Partnership) with a total value in excess of £5M and is the Principal Investigator of an EPSRC first grant award that is aiding the development of novel haemorheometrical techniques for the measurement of blood coagulation and subsequent breakdown.

Areas of Expertise

  • Rheometry
  • Haemorheology
  • Biopolymer gels

Publications

  1. & Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood. Blood 116(17), 3341-3346.
  2. & In-situ synthesis of magnetic iron-oxide nanoparticle-nanofibre composites using electrospinning. Materials Science and Engineering: C 70, 512-519.
  3. & Platelet reactivity influences clot structure as assessed by fractal analysis of viscoelastic properties. Platelets, 1-9.
  4. & i-Rheo: Measuring the materials' linear viscoelastic properties “in a step”!. Journal of Rheology 60(4), 649-660.
  5. & Effects of exercise intensity on clot microstructure and mechanical properties in healthy individuals. Thrombosis Research 143, 130-136.

See more...

Teaching

  • PM-230 Selected Medical Diagnostic Techniques

    This module looks at the design and operation of a wide range of instrumentation used to make measurements for diagnostic and monitoring purposes. The emphasis is on the underlying electrical, mechanical, chemical, optical and other engineering principles.

  • PM-304 Biomolecular Research Project

    *

  • PM-M16 Nano(geno)toxicology

    Nano(geno)toxicology is a new discipline that has recently evolved with the development of the nanotechnology industry. This subject encompasses general toxicology associated with nanomaterials and also specifically focuses on the sub-discipline of genotoxicology. This course will therefore focus on, (I) the parameters of engineered nanomaterials that govern their interaction and influence on biological systems; (II) techniques that are central elements in assessing the safety evaluation of nanomaterials; (III) portals of entry into the body, their potential fate and the mechanisms that underlie cellular damage by nanomaterials.

  • PM-M28 Nano(geno)toxicology

    Nano(geno)toxicology is a new discipline that has recently evolved with the development of the nanotechnology industry. This subject encompasses general toxicology associated with nanomaterials and also specifically focuses on the sub-discipline of genotoxicology. This course will therefore focus on, (I) the parameters of engineered nanomaterials that govern their interaction and influence on biological systems; (II) techniques that are central elements in assessing the safety evaluation of nanomaterials; (III) portals of entry into the body, their potential fate and the mechanisms that underlie cellular damage by nanomaterials.

  • PMND00 Nanomedicine Research Dissertation

    This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study within nanomedicine.

  • PMNM02 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

  • PMNM07 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

  • PMZM13 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

Supervision

  • Rheological measurement of abnormal blood clot micrpstructures: A novel marker for prediciting embolic risk (current)

    Student name:
    PhD
    Other supervisor: Dr Karl Hawkins
    Other supervisor: Professor Adrian Evans
  • Development of advanced ionisation techniques for mass spectrometry (current)

    Student name:
    PhD
    Other supervisor: Dr Ruth Godfrey
    Other supervisor: Dr Karl Hawkins
  • Impact of ventricular assist devices on the activity of white blood cells and the implications for device design and testing. (current)

    Student name:
    PhD
    Other supervisor: Prof Catherine Thornton
    Other supervisor: Dr Karl Hawkins
  • Analysis of the effect of mechanical heart pumps on the blood components (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr Karl Hawkins
  • The fabrication of novel polymer scaffolds for regenerative medicine based on collagen derived from jelly fish. (current)

    Student name:
    PhD
    Other supervisor: Dr Christopher Wright
    Other supervisor: Dr Karl Hawkins
  • Development of a Novel Haemo-Rheological Test and Biomarker and its Evaluation in Patients with Stroke (current)

    Student name:
    PhD
    Other supervisor: Dr Karl Hawkins
    Other supervisor: Professor Adrian Evans

Administrative Responsibilities

  • Research Theme Lead - Devices

    2016 - Present

  • Programme Director - MSc Nanomedicine

    2014 - Present

  • Member - Medical School Research Committee

    2016 - Present

  • Member - Medical School Learning and Teaching Committee

    2016 - Present

  • Member - Medical School REF Committee

    2015 - Present

  • Member - Medical School Postgraduate Taught Studies Committee

    2014 - Present

Career History

Start Date End Date Position Held Location
2012 Present Associate Professor Swansea University Medical School
2007 2012 RCUK Fellow Swansea University Medical School
2007 Present Research Fellow ABM University Health Board
2007 2007 Visiting Researcher (British Council RXP) Penn Medicine, University of Pennsylvania, USA
2005 2007 Postdoctoral Research Officer Swansea University College of Engineering