About Me

Areas of Expertise

  • Molecular microbiology
  • Gene expression analysis
  • Cell biology
  • Bacterial symbionts of insects
  • Tumour-targetting bacteria

Publications

  1. & Targeting the Osmotic Stress Response for Strain Improvement of an Industrial Producer of Secondary Metabolites. J. Microbiol. Biotechnol. 25(11), 1787-1795.
  2. & Complete genome sequence of a psychotrophic Arthrobacter strain A3 (CGMCC 1.8987), a novel long-chain hydrocarbons producer. Journal of Biotechnology 222, 23-24.
  3. & Symbiont-mediated RNA interference in insects. Proceedings of the Royal Society B: Biological Sciences 283(1825), 20160042
  4. & Complete genome sequence of a psychotrophic Pseudarthrobacter sulfonivorans strain Ar51 (CGMCC 4.7316), a novel crude oil and multi benzene compounds degradation strain. Journal of Biotechnology 231, 81-82.
  5. & Draft Genomes, Phylogenetic Reconstruction, and Comparative Genomics of Two Novel Cohabiting Bacterial Symbionts Isolated fromFrankliniella occidentalis. Genome Biology and Evolution 7(8), 2188-2202.

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Teaching

  • PM-226 Human and Medical Genetics

    The course is designed to introduce fundamental concepts in the study of human genetics with particular reference to the application of the principles to medicine. The course covers the role of genetics in human health and disease and methods for the detection of genetic variability in human populations.

  • PM-251 Microbial Molecular Genetics

    The control systems governing gene expression in prokaryotic cells are explored and the molecular basis for gene regulation introduced. Practical skills in obtaining and analysing data on a bacterial system are developed. The module then assesses the structure of the bacterial genome and how genetic analysis can be used to investigate structure and function of individual components of that genome. Specific examples explored in depth are the genetics of recombination and DNA repair. The technologies used for functional genomic analysis of fully sequenced bacteria are described with reference to analysis of human pathogens. Finally, the module includes examples of synthetic biology applied to bacteria.

  • PM-308 Animal Development

    The module provides an understanding of the principles of animal development, introducing critical genes and their products that play roles in regulating metazoan development. Classical embryology will be integrated with contemporary molecular investigations into developmental mechanisms.

  • PM-314 Biotechnology & Protein Engineering

    The module aims to explain the biological basis of biotechnology and protein engineering: their limitations, industrial and medical importance. Students will develop their skills in gathering and interpreting relevant information.

  • PM-315 Genetic Analysis III

    The module aims to develop the student’s ability to critically analyse and synthesise advanced research topics in genetics and molecular biology, and their oral and written scientific presentation skills.

Supervision

  • Molecular characterization of Frankliniella occidentails gut symbionts: Implications to the design of novel bio-pesticides (current)

    Student name:
    PhD
    Other supervisor: Dr Ricardo Del Sol Abascal
  • Untitled (current)

    Student name:
    MSc
    Other supervisor: Dr Ricardo Del Sol Abascal
  • Post Transcriptional gene silencing of Trypanosoma brucei procyclic trypomastigotes using dsRNA expressing Sodalis glossiniduis. (current)

    Student name:
    MSc
    Other supervisor: Dr Miranda Walker (Nee Whitten)
  • Microbial pathogenicity and immune response’ (current)

    Student name:
    PhD
    Other supervisor: Professor Catherine Thornton
  • 'Investigations into the antimicrobial properties of various invertebrates' (awarded 2015)

    Student name:
    PhD
    Other supervisor: Dr Yamni Nigam
  • 'Exploring the roles of novel secondary metabolites in streptomycetes' (awarded 2014)

    Student name:
    PhD
    Other supervisor: Professor David Lamb
    Other supervisor: Professor Steven Kelly
  • 'Biochemical and structural analysis of the Dps proteins of Streptomyces coelicolor' (awarded 2014)

    Student name:
    PhD
    Other supervisor: Dr Ricardo Del Sol Abascal
  • 'Regulation ofl osmoadaptation in streptomyces coelicolor A3(2)' (awarded 2013)

    Student name:
    PhD
    Other supervisor: Dr Hugh Jones
  • 'Sporulation septation in Strptomyces as a model to investigate bacterial cell division.' (awarded 2013)

    Student name:
    PhD
    Other supervisor: Dr Ricardo Del Sol Abascal
  • Functional analysis of a novel DNA binding protein of Streptomyces coelicolor (awarded 2012)

    Student name:
    PhD
    Other supervisor: Dr Hugh Jones
  • Microbial community analysis of constructed wetlands treating effluent from a land-based marine fish farm (awarded 2008)

    Student name:
    PhD
    Other supervisor: Dr Robin Shields
  • Analysis of SEDS proteins and their cognate PBPs in Streptomyces coelicolor (awarded 2008)

    Student name:
    PhD
  • Investigations into the osmotic stress response mediated by OsaB in streptomyces coelicolor A3(2) (awarded 2008)

    Student name:
    PhD
    Other supervisor: Dr Hugh Jones
  • Interactions between orthologs of conserved actinomyce proteins (awarded 2007)

    Student name:
    MPhil
    Other supervisor: Dr Hugh Jones
  • A conserved Gram-positive signalling gene cluster: phylogeny and function (awarded 2007)

    Student name:
    PhD
    Other supervisor: Dr Hugh Jones
  • Untitled (awarded 2006)

    Student name:
    PhD
    Other supervisor: Dr Hugh Jones