I studied both my BSc and MSc in Biomedical Science in University of Wales Institute, Cardiff, specialising in Forensic Toxicology and Medical Microbiology. Following this I was fortunate enough to be awarded a NISCHR Welsh Office of Research and Development PhD (2009), investigating the role of exercise in preventing the progression of Type 2 diabetes and associated cardiovascular effects e.g. atherosclerosis and cell polarisation effects. This allowed me the opportunity to carry out in vivo projects and develop a keen interest in the effects of inflammation on cell signalling pathways and their role in disease progression.

My time as a post-Doctoral researcher was spent in the Haemostasis Biomedical Research Unit, investigating the role of inflammation in haemostasis and how this varies in hypo- and hyper-coagulable states. Based in an Emergency Department in Morriston Hospital, I developed a keen interest in Emergency Medicine Research and was involved in a number of studies investigating the role of haemostasis in stroke, cardiac, sepsis and burns patients. I successfully led and completed a project investigating the changes in haemostasis in patients with lung cancer, quantifying changes to clot structure using a cutting edge haemorheological technique, developed here in Swansea University between Medical School and the College of Engineering.

Currently I am director of the Foundation Year for the BSc Applied Medical Sciences degree programme, aiming to widen access to Higher Education. In addition I am a lecturer and disability link tutor on the BSc Applied Medical Sciences, co-ordinating and contributing to several modules including laboratory skills, anatomy, physiology and pathophysiology.  

Publications

  1. & An Investigation Into the Effects of In Vitro Dilution With Different Colloid Resuscitation Fluids on Clot Microstructure Formation. Anesthesia & Analgesia 123(5), 1081-1088.
  2. Fractal dimension (df) as a new structural biomarker of clot microstructure in different stages of lung cancer. Thrombosis and Haemostasis 114(6), 1251-1259.
  3. Application of ROTEM to assess hypercoagulability in patients with lung cancer. Thrombosis Research 135(6), 1075-1080.
  4. & PO-25 - FATCAT: an observational cohort study investigating fractal dimension (df) as a biomarker of thrombogenicity in cancer associated thrombosis during chemotherapy for lung cancer. Thrombosis Research 140, S185
  5. & Effects of exercise intensity on clot microstructure and mechanical properties in healthy individuals. Thrombosis Research 143, 130-136.

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Teaching

  • PM-002 The Human Cell

    This module will provide the learner with a broad overview of the human body, from cell structure and organisation to organs and organ systems. The module will focus on blood; in particular how it functions in the circulatory system and infection. Cancer cell proliferation will be introduced in this module via haematological malignancies. This module will be supported by 2 practical sessions and essay with academic support.

  • PM-003 Introduction to Molecular Biology

    This module will provide the learner with an introduction to molecular biology, classification of species and its applications in medical science. The concept of evolution and sexual reproduction and development will also be covered, and the processes of inheritance and genetic variation, particularly with regard to evolution and natural selection. This module will be supported by 2 practical sessions and essay with academic support on a topic relevant to the medical applications of molecular biology.

  • PM-007 Foundation Applied Medical Sciences Skills Development 1

    The module will provide the student with a diversity of study, laboratory and scientific skills in relation to the undertaking of undergraduate practical sessions in a safe manner. This will involve the development of skills including basic biologically relevant mathematics, appropriate data handling, working safely and key laboratory skills. Students will also be provided with an introduction to laboratory methods such as accurate pipetting and standard curve construction.In addition, students will receive lectures on developing study skills in literature searching, referencing & plaigarism and communication of information.

  • PM-008 Foundation Applied Medical Sciences Skills Development 2

    The module will provide the student with a diversity of laboratory and scientific skills in relation to the undertaking of undergraduate practical sessions in a safe manner and develop skills including molarity calculations, biological extractions, basic chromatography, an introduction into anatomical dissection and physiology.

  • PM-138 Skills for Medical Sciences

    The aim of this module is to provide the student with basic skills required for laboratory research in the field of applied medical sciences. The module will be both theoretical and applied: the student will be instructed in methods essential for data acquisition and analyses but will also actively participate in the laboratory, using broadly applicable experimental techniques. They will also develop skills that are not experimental techniques themselves, but are nevertheless fundamental to the scientific process, such as `lab math,¿ sourcing information, referencing, ethics and health and safety.

  • PM-138C Sgiliau ar gyfer Gwyddorau Meddygol

    Nod y modiwl hwn yw darparu¿r sgiliau sylfaenol sydd eu hangen ar fyfyrwyr ar gyfer ymchwil labordy ym maes y gwyddorau meddygol cymhwysol. Bydd y modiwl yn cynnwys gwaith damcaniaethol a chymhwysol: caiff y myfyriwr ei hyfforddi mewn dulliau sy¿n hanfodol ar gyfer caffael data a¿i ddadansoddi, ond bydd hefyd yn cymryd rhan weithredol yn y labordy, gan ddefnyddio¿n fras y technegau arbrofol perthnasol. Byddant hefyd yn datblygu sgiliau nad ydynt yn dechnegau arbrofol yn eu hunain, ond sydd er hynny, yn sylfaenol i¿r broses wyddonol, megis, mathemateg y labordy¿, cyrchu gwybodaeth, cyfeirnodi, moeseg ac iechyd a diogelwch.

  • PM-139 Human Physiology I

    This module aims to provide an understanding of the structure and function of key physiological systems of the human body. Human physiology is the study of how our body works in an integrated way. A central principle of human physiology is homeostasis, the maintenance of a relatively stable internal environment. Failure to maintain homeostasis disrupts normal function that may lead to disease (or pathophysiology). Students will be taught the key concepts of homeostasis in the physiological systems of the body, enabling the student to understand the consequences of pathophysiology to human health. Students will gain practical experience in assessing respiration and cardiac function during two separate laboratory based exercises

  • PM-140 Anatomy

    This module will provide knowledge of the structure of the human body, and how this adult anatomy develops. It will study human anatomy in a systems approach, focusing on the cardiovascular, gastrointestinal, musculoskeletal, urogenital, and nervous systems. Anatomy is a fundamental science and supports many areas of biology. As such the topics chosen for this module are those most useful to other areas of biological science, and are often clinically significant. This module will use practical classes to study human tissue and will develop the skills needed to dissect and study cadavers. Support materials and laboratory space for self directed learning will be available, including plastic anatomical models, bones and skeletons, and computer based anatomical models.

  • PM-141 Human Physiology II

    This module aims to provide students with further understanding of human physiology through studies on systems physiology including the endocrine, renal, blood, digestive/metabolism and reproductive system. The module will equally describe how malfunction of physiological systems gives rise to disease, using specific examples to enable students to appreciate the relationship between physiology/anatomy and medicine. Fundamental principles of physiology will be illustrated with appropriate clinical examples and during practical assignments.

  • PM-259 Contemporary themes and techniques in medical sciences

    This module aims to give students an overview of current and emerging themes in medical sciences, both from clinical and laboratory perspectives. This will cover topics generating high media interest, such as zika virus and alternative methods of transplantation as well as new laboratory techniques used in clinical trials such as Rama spectroscopy in the identification of cancer cells. In addition, the module will be supported by 2 practical classes for which students will be required to conduct mini-projects based around the identification of patient samples and how these are presented as research cases.