Publications

Journal Articles

  1. Pertusati, F., Ferla, S., Bassetto, M., Brancale, A., Khandil, S., Westwell, A., McGuigan, C. A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer European Journal of Medicinal Chemistry 180 1 14
  2. Bassetto, M., Van Dycke, J., Neyts, J., Brancale, A., Rocha-Pereira, J. Targeting the Viral Polymerase of Diarrhea-Causing Viruses as a Strategy to Develop a Single Broad-Spectrum Antiviral Therapy Viruses 11 2 173
  3. Bassetto, M., Slusarczyk, M. Therapeutic use of fluorinated nucleosides – progress in patents Pharmaceutical Patent Analyst 7 6 277 299
  4. Giancotti, G., Cancellieri, M., Balboni, A., Giustiniano, M., Novellino, E., Delang, L., Neyts, J., Leyssen, P., Brancale, A., Bassetto, M. Rational modifications on a benzylidene-acrylohydrazide antiviral scaffold, synthesis and evaluation of bioactivity against Chikungunya virus European Journal of Medicinal Chemistry 149 56 68
  5. Ferla, S., Netzler, N., Ferla, S., Veronese, S., Tuipulotu, D., Guccione, S., Brancale, A., White, P., Bassetto, M. In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase Scientific Reports 8 1
  6. Tardugno, R., Giancotti, G., De Burghgraeve, T., Delang, L., Neyts, J., Leyssen, P., Brancale, A., Bassetto, M. Design, synthesis and evaluation against Chikungunya virus of novel small-molecule antiviral agents Bioorganic & Medicinal Chemistry 26 4 869 874
  7. Bassetto, M., Ferla, S., Giancotti, G., Pertusati, F., Westwell, A., Brancale, A., McGuigan, C. Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents MedChemComm 8 7 1414 1420
  8. Brancale, A., Shailubhai, K., Ferla, S., Ricci, A., Bassetto, M., Jacob, G. Therapeutically targeting guanylate cyclase-C: computational modeling of plecanatide, a uroguanylin analog Pharmacology Research & Perspectives 5 2 e00295
  9. Bassetto, M., Leyssen, P., Neyts, J., Yerukhimovich, M., Frick, D., Brancale, A. Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV Bioorganic & Medicinal Chemistry Letters 27 4 936 940
  10. Bassetto, M., Leyssen, P., Neyts, J., Yerukhimovich, M., Frick, D., Courtney-Smith, M., Brancale, A. In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase European Journal of Medicinal Chemistry 125 1115 1131
  11. Bassetto, M., Leyssen, P., Neyts, J., Yerukhimovich, M., Frick, D., Brancale, A. Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication European Journal of Medicinal Chemistry 123 31 47
  12. Bassetto, M., Massarotti, A., Coluccia, A., Brancale, A. Structural biology in antiviral drug discovery Current Opinion in Pharmacology 30 116 130
  13. Bassetto, M., Ferla, S., Pertusati, F., Kandil, S., Westwell, A., Brancale, A., McGuigan, C. Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer European Journal of Medicinal Chemistry 118 230 243
  14. Bassetto, M., Ferla, S., Leyssen, P., Neyts, J., Yerukhimovich, M., Frick, D., O’Donnell, R., Brancale, A. Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents Antiviral Chemistry and Chemotherapy 24 5-6 155 160
  15. Cancellieri, M., Bassetto, M., Widjaja, I., van Kuppeveld, F., de Haan, C., Brancale, A. In silico structure-based design and synthesis of novel anti-RSV compounds Antiviral Research 122 46 50
  16. Bassetto, M., Ferla, S., Pertusati, F. Polyfluorinated groups in medicinal chemistry Future Medicinal Chemistry 7 4 527 546
  17. Wang, X., Liu, L., Huang, L., Herbst-Robinson, K., Cornec, A., James, M., Sugiyama, S., Bassetto, M., Brancale, A., Trojanowski, J., Lee, V., Smith, A., Brunden, K., Ballatore, C. Potent, Long-Acting Cyclopentane-1,3-Dione Thromboxane (A2)-Receptor Antagonists ACS Medicinal Chemistry Letters 5 9 1015 1020
  18. Romagnoli, R., Baraldi, P., Lopez-Cara, C., Salvador, M., Preti, D., Tabrizi, M., Balzarini, J., Nussbaumer, P., Bassetto, M., Brancale, A., Fu, X., Yang-Gao, ., Li, J., Zhang, S., Hamel, E., Bortolozzi, R., Basso, G., Viola, G. Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents Bioorganic & Medicinal Chemistry 22 18 5097 5109
  19. Bassetto, M., De Burghgraeve, T., Delang, L., Massarotti, A., Coluccia, A., Zonta, N., Gatti, V., Colombano, G., Sorba, G., Silvestri, R., Tron, G., Neyts, J., Leyssen, P., Brancale, A. Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus Antiviral Research 98 1 12 18
  20. Romagnoli, R., Baraldi, P., Lopez-Cara, C., Preti, D., Aghazadeh Tabrizi, M., Balzarini, J., Bassetto, M., Brancale, A., Fu, X., Gao, Y., Li, J., Zhang, S., Hamel, E., Bortolozzi, R., Basso, G., Viola, G. Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents Journal of Medicinal Chemistry 56 22 9296 9309
  21. Romagnoli, R., Baraldi, P., Kimatrai Salvador, M., Preti, D., Aghazadeh Tabrizi, M., Bassetto, M., Brancale, A., Hamel, E., Castagliuolo, I., Bortolozzi, R., Basso, G., Viola, G. Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents Journal of Medicinal Chemistry 56 6 2606 2618
  22. Romagnoli, R., Baraldi, P., Salvador, M., Camacho, M., Preti, D., Tabrizi, M., Bassetto, M., Brancale, A., Hamel, E., Bortolozzi, R., Basso, G., Viola, G. Synthesis and biological evaluation of 2-substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents Bioorganic & Medicinal Chemistry 20 24 7083 7094