Dr Andrew Warrilow
Research Officer
Medicine
Telephone: (01792) 295828
Room: Academic Office - 527
Fifth Floor
Institute of Life Science 1
Singleton Campus

Areas of Expertise

  • Sterol 14-alpha demethylases (CYP51)
  • NADPH-Cytochrome P450 reductases
  • Azole antifungals (pharmazoles and agriazoles)
  • Enzymology
  • Protein Biochemistry
  • Protein Purification
  • Centre for Cytochrome P450 Biodiversity Homepage ( http://www.p450swansea.co.uk/ )
  • Co-investigator on BEACON ( http://www.beaconwales.org )

Publications

  1. & Functional importance for developmental regulation of sterol biosynthesis in Acanthamoeba castellanii. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1863(10), 1164-1178.
  2. et. al. In Vitro and In Vivo Efficacy of a Novel and Long Acting Fungicidal Azole, PC1244 on Aspergillus fumigatus Infection. Antimicrobial Agents and Chemotherapy, AAC.01941-17
  3. & Co-production of 11α-hydroxyprogesterone and ethanol using recombinant yeast expressing fungal steroid hydroxylases. Biotechnology for Biofuels 10(1)
  4. et. al. In vitro and in vivo antifungal profile of a novel and long acting inhaled azole, PC945, on Aspergillus fumigatus infection. Antimicrobial Agents and Chemotherapy, AAC.02280-16
  5. & The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51. Antimicrobial Agents and Chemotherapy 61(7), e00333-17

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Teaching

  • PM-357 Biomedical Laboratory Techniques

    The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.

  • PM-357C Technegau Labordy Biofeddygol

    Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.