Areas of Expertise

  • Toxicology
  • DNA damage
  • Cell biology
  • Image analysis

Publications

  1. Shah, U., Seager, A., Fowler, P., Doak, S., Johnson, G., Scott, S., Scott, A., Jenkins, G. A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity Mutation Research/Genetic Toxicology and Environmental Mutagenesis 808 8 19
  2. Patni, S., Wynen, L., Seager, A., Morgan, G., White, J., Thornton, C. Expression and Activity of Toll-Like Receptors 1–9 in the Human Term Placenta and Changes Associated with Labor at Term Biology of Reproduction 80 2 243 248
  3. Macfarlane, T., Seager, A., Moller, M., Morgan, G., Thornton, C. Thymic stromal lymphopoietin is present in human breast milk Pediatric Allergy and Immunology 21 2p2 e454 e456
  4. Seager, A., Shah, U., Mikhail, J., Nelson, B., Marquis, B., Doak, S., Johnson, G., Griffiths, S., Carmichael, P., Scott, S., Scott, A., Jenkins, G., Jenkins, G., Doak, S., Seager, A., Johnson, G., Mikhail, J. Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance Toxicological Sciences 128 2 387 397
  5. Seager, A., Shah, U., Brusehafer, K., Wills, J., Manshian, B., Chapman, K., Thomas, A., Scott, A., Doherty, A., Doak, S., Johnson, G., Jenkins, G., Jenkins, G., Doak, S., Seager, A., Johnson, G., Bruesehafer, K., Shah, U., Chapman, K. Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells Mutagenesis 29 3 155 164

Teaching

  • PM-147 The Dose Makes the Poison: Intro to Toxicology and Dose Response

    We are surrounded by substances that may do our bodies harm ¿ poisons. The harm these poisons causes depends on our exposure - the dose. The science of toxicology, a discipline that crosscuts biology, chemistry, pharmacology, and medicine, is based on the principle that the dose makes the poison. This module will provide you with an introduction to toxicology and how dose-response relationships relate to the physiological effects of toxic substances. You will explore how they produce cellular and chemical changes that cause tissues and organs to malfunction. You will learn how the structure and function of these tissues can be affected to varying degrees and begin to understand how tissue may repair itself and when the damage is permanent or fatal.

  • PM-315 Skills For Geneticists III

    The module aims to develop the student¿s ability to critically analyse and synthesise advanced research topics in genetics and molecular biology, and their oral and written scientific presentation skills.

  • PM-315C Sgiliau ar gyfer Genetegwyr III

    Amcan y modiwl yw datblygu gallu'r myfyriwr i ddadansoddi'n feirniadol a syntheseiddio pynciau ymchwil uwch ym maes geneteg a bioleg foleciwlaidd, ac i feithrin eu sgiliau cyflwyno gwyddonol llafar ac ysgrifenedig.

  • PM-317 Genetics of Cancer

    This module will provide students with an advanced understanding about the genetic mechanisms involved in carcinogenesis, and how these underlying processes and molecules affect the human body.

  • PMRM00 Introduction to the practice of Medical Physicists & Clinical Engineers in Health Care

    Provides a broad-based overview of the Medical Physics & Clinical Engineering discipline.

Administrative Responsibilities