1. Warrilow, Andrew G.S.., Parker, Josie E.., Price, Claire L.., Rolley, Nicola J.., Nes, W. David., Kelly, Diane E.. & Kelly, Steven L.. (2019). Isavuconazole and voriconazole inhibition of sterol 14α-demethylases (CYP51) from Aspergillus fumigatus and Homo sapiens. International Journal of Antimicrobial Agents

   https://cronfa.swan.ac.uk/Record/cronfa51181 doi:10.1016/j.ijantimicag.2019.07.011
2. Rybak, Jeffrey M.., Ge, Wenbo., Wiederhold, Nathan P.., Parker, Josie E.., Kelly, Steven L.., Rogers, P. David. & Fortwendel, Jarrod R.. (2019). Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus. mBio 10(2)

   https://cronfa.swan.ac.uk/Record/cronfa49873 doi:10.1128/mBio.00437-19
3. Warrilow, Andrew G.., Nishimoto, Andrew T.., Parker, Josie E.., Price, Claire L.., Flowers, Stephanie A.., Kelly, Diane E.., Rogers, P. David. & Kelly, Steven L.. (2019). The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions. Antimicrobial Agents and Chemotherapy

   https://cronfa.swan.ac.uk/Record/cronfa48946 doi:10.1128/AAC.02586-18
4. Griffiths, William J.., Crick, Peter J.., Meljon, Anna., Theofilopoulos, Spyridon., Abdel-Khalik, Jonas., Yutuc, Eylan., Parker, Josie E.., Kelly, Diane E.., Kelly, Steven L.., Arenas, Ernest. & Wang, Yuqin. (2019). Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1864(2), 191-211.

   https://cronfa.swan.ac.uk/Record/cronfa46175 doi:10.1016/j.bbalip.2018.11.006
5. Ahmad, Suhail., Joseph, Leena., Parker, Josie E.., Asadzadeh, Mohammad., Kelly, Steven L.., Meis, Jacques F.. & Khan, Ziauddin. (2018). ERG6 and ERG2 Are Major Targets Conferring Reduced Susceptibility to Amphotericin B in Clinical Candida glabrata Isolates in Kuwait. Antimicrobial Agents and Chemotherapy 63(2), e01900-18

   https://cronfa.swan.ac.uk/Record/cronfa46174 doi:10.1128/AAC.01900-18
6. Zhou, Wenxu., Warrilow, Andrew G.S.., Thomas, Crista D.., Ramos, Emilio., Parker, Josie E.., Price, Claire L.., Vanderloop, Boden H.., Fisher, Paxtyn M.., Loftis, Michael D.., Kelly, Diane E.., Kelly, Steven L.. & Nes, W. David. (2018). Functional importance for developmental regulation of sterol biosynthesis in Acanthamoeba castellanii. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1863(10), 1164-1178.

   https://cronfa.swan.ac.uk/Record/cronfa41148 doi:10.1016/j.bbalip.2018.07.004
7. Luna-Tapia, Arturo., Willems, Hubertine M. E.., Parker, Josie E.., Tournu, Hélène., Barker, Katherine S.., Nishimoto, Andrew T.., Rogers, P. David., Kelly, Steven L.., Peters, Brian M.. & Palmer, Glen E.. (2018). Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity. mBio 9(3), e00225-18

   https://cronfa.swan.ac.uk/Record/cronfa40413 doi:10.1128/mBio.00225-18
8. Colley, Thomas., Sehra, Gurpreet., Chowdhary, Anuradha., Alanio, Alexandre., Kelly, Steven L.., Kizawa, Yasuo., Armstrong-James, Darius., Fisher, Matthew C.., Warrilow, Andrew G.S.., Parker, Josie E.., Kelly, Diane E.., Kimura, Genki., Nishimoto, Yuki., Sunose, Mihiro., Onions, Stuart., Crepin, Damien., Lagasse, Franz., Crittall, Matthew., Shannon, Jonathan., et. al. (2018). In Vitro and In Vivo Efficacy of a Novel and Long Acting Fungicidal Azole, PC1244 on Aspergillus fumigatus Infection. Antimicrobial Agents and Chemotherapy, AAC.01941-17

   https://cronfa.swan.ac.uk/Record/cronfa39297 doi:10.1128/AAC.01941-17
9. Butts, A., DeJarnette, C., Peters, T., Parker, J., Kerns, M., Eberle, K., Kelly, S. & Palmer, G. (2017). Target Abundance-Based Fitness Screening (TAFiS) Facilitates Rapid Identification of Target-Specific and Physiologically Active Chemical Probes. mSphere 2(5), e00379-17

   https://cronfa.swan.ac.uk/Record/cronfa36657 doi:10.1128/mSphere.00379-17
10. Rybak, J., Dickens, C., Parker, J., Caudle, K., Manigaba, K., Whaley, S., Nishimoto, A., Luna-Tapia, A., Roy, S., Zhang, Q., Barker, K., Palmer, G., Sutter, T., Homayouni, R., Wiederhold, N., Kelly, S. & Rogers, P. (2017). Loss of C-5 sterol desaturase activity results in increased resistance to azole and echinocandin antifungals in a clinical isolate of Candida parapsilosis. Antimicrobial Agents and Chemotherapy, AAC.00651-17

    https://cronfa.swan.ac.uk/Record/cronfa34719 doi:10.1128/AAC.00651-17
11. Warrilow, A., Parker, J., Price, C., Garvey, E., Hoekstra, W., Schotzinger, R., Wiederhold, N., Nes, W., Kelly, D. & Kelly, S. (2017). The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51. Antimicrobial Agents and Chemotherapy 61(7), e00333-17

    https://cronfa.swan.ac.uk/Record/cronfa34720 doi:10.1128/AAC.00333-17
12. Colley, T., Alanio, A., Kelly, S., Sehra, G., Kizawa, Y., Warrilow, A., Parker, J., Kelly, D., Kimura, G., Anderson-Dring, L., Nakaoki, T., Sunose, M., Onions, S., Crepin, D., Lagasse, F., Crittall, M., Shannon, J., Cooke, M., Bretagne, S., et. al. (2017). In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection. Antimicrobial Agents and Chemotherapy 61(5), e02280-16

    https://cronfa.swan.ac.uk/Record/cronfa33103 doi:10.1128/AAC.02280-16
13. McCourt, P., Liu, H., Parker, J., Gallo-Ebert, C., Donigan, M., Bata, A., Giordano, C., Kelly, S. & Nickels, J. (2016). Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence. G3: Genes|Genomes|Genetics

    https://cronfa.swan.ac.uk/Record/cronfa32088 doi:10.1534/g3.116.033969
14. Warrilow, A., Parker, J., Price, C., Nes, W., Garvey, E., Hoekstra, W., Schotzinger, R., Kelly, D. & Kelly, S. (2016). The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme. Antimicrobial Agents and Chemotherapy 60(8), 4530-4538.

    https://cronfa.swan.ac.uk/Record/cronfa29213 doi:10.1128/AAC.00349-16
15. Warrilow, A., Price, C., Parker, J., Rolley, N., Smyrniotis, C., Hughes, D., Thoss, V., Nes, W., Kelly, D., Holman, T. & Kelly, S. (2016). Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa. Scientific Reports 6, 27690

    https://cronfa.swan.ac.uk/Record/cronfa29214 doi:10.1038/srep27690
16. Berkow, E., Manigaba, K., Parker, J., Barker, K., Kelly, S. & Rogers, P. (2015). Multidrug transporters and alterations in sterol biosynthesis contribute to azole antifungal resistance inCandida parapsilosis. Antimicrobial Agents and Chemotherapy, AAC.01358-15

    https://cronfa.swan.ac.uk/Record/cronfa22523 doi:10.1128/AAC.01358-15
17. Derbyshire, M., Michaelson, L., Parker, J., Kelly, S., Thacker, U., Powers, S., Bailey, A., Hammond-Kosack, K., Courbot, M. & Rudd, J. (2015). Analysis of cytochrome b5 reductase-mediated metabolism in the phytopathogenic fungus Zymoseptoria tritici reveals novel functionalities implicated in virulence. Fungal Genetics and Biology

    https://cronfa.swan.ac.uk/Record/cronfa22091 doi:10.1016/j.fgb.2015.05.008
18. Lamb, D., Warrilow, A., Rolley, N., Parker, J., Nes, W., Smith, S., Kelly, D. & Kelly, S. (2015). Azole antifungal agents to treat the human pathogensAcanthamoeba castellanii and Acanthamoeba polyphagathrough inhibition of sterol 14α-demethylase (CYP51). Antimicrobial Agents and Chemotherapy, AAC.00476-15

    https://cronfa.swan.ac.uk/Record/cronfa21904 doi:10.1128/AAC.00476-15
19. Price, C., Parker, J., Warrilow, A., Kelly, D. & Kelly, S. (2015). Azole fungicides - understanding resistance mechanisms in agricultural fungal pathogens. Pest Management Science 71(8), 1054-1058.

    https://cronfa.swan.ac.uk/Record/cronfa21903 doi:10.1002/ps.4029
20. (2015). In Vitro Biochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy 59(12), 7771-7778.

    https://cronfa.swan.ac.uk/Record/cronfa29212 doi:10.1128/AAC.01806-15
21. Price, C., Warrilow, A., Parker, J., Mullins, J., Nes, W., Kelly, D., Kelly, S. & Schottel, J. (2015). Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase. Applied and Environmental Microbiology 81(10), 3379-3386.

    https://cronfa.swan.ac.uk/Record/cronfa21902 doi:10.1128/AEM.03965-14
22. Warrilow, A., Hull, C., Rolley, N., Parker, J., Nes, W., Smith, S., et. al. (2014). Clotrimazole as a Potent Agent for Treating the Oomycete Fish Pathogen Saprolegnia parasitica through Inhibition of Sterol 14 -Demethylase (CYP51). Applied and Environmental Microbiology 80(19), 6154-6166.

    https://cronfa.swan.ac.uk/Record/cronfa19341 doi:10.1128/AEM.01195-14
23. Parker, J., Warrilow, A., Price, C., Mullins, J., Kelly, D. & Kelly, S. (2014). Resistance to antifungals that target CYP51. Journal of Chemical Biology 7(4), 143-161.

    https://cronfa.swan.ac.uk/Record/cronfa19342 doi:10.1007/s12154-014-0121-1
24. Warrilow, A., Hull, C., Parker, J., Garvey, E., Hoekstra, W., Moore, W., et. al. (2014). The Clinical Candidate VT-1161 Is a Highly Potent Inhibitor of Candida albicans CYP51 but Fails To Bind the Human Enzyme. Antimicrobial Agents and Chemotherapy 58(12), 7121-7127.

    https://cronfa.swan.ac.uk/Record/cronfa19343 doi:10.1128/AAC.03707-14
25. Warrilow, A. Parker, J. Kelly, D. & Kelly, S. (2013). Azole Affinity of Sterol 14 -Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens. Antimicrobial Agents and Chemotherapy 57(3)-1360.

    https://cronfa.swan.ac.uk/Record/cronfa14419 doi:10.1128/AAC.02067-12
26. Parker, J. Warrilow, A. Cools, H. Fraaije, B. Lucas, J. Rigdova, K. Griffiths, W. Kelly, D. & Kelly, S. (2013). Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14- -Demethylase. Applied and Environmental Microbiology 79(5)-1645.

    https://cronfa.swan.ac.uk/Record/cronfa14420 doi:10.1128/AEM.03246-12
27. Fan, J. Urban, M. Parker, J. Brewer, H. Kelly, S. Hammond-Kosack, K. Fraaije, B. Liu, X. & Cools, H. (2013). Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. New Phytologist-n/a.

    https://cronfa.swan.ac.uk/Record/cronfa14421 doi:10.1111/NPH.12193
28. Eddouzi, J. Parker, J. Vale-Silva, L. Coste, A. Ischer, F. Kelly, S. Manai, M. & Sanglard, D. (2013). Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals. Antimicrobial Agents and Chemotherapy 57(7)-3193.

    https://cronfa.swan.ac.uk/Record/cronfa15734 doi:10.1128/AAC.00555-13
29. Nie, D. Hoobler, E. Rai, G. Warrilow, A. Perry, S. Smyrniotis, C. Jadhav, A. Simeonov, A. Parker, J. Kelly, D. Maloney, D. Kelly, S. & Holman, T. (2013). Discovery of a Novel Dual Fungal CYP51/Human 5-Lipoxygenase Inhibitor: Implications for Anti-Fungal Therapy. PLoS ONE 8(6)

    https://cronfa.swan.ac.uk/Record/cronfa15735 doi:10.1371/journal.pone.0065928
30. Vale-Silva, L. Coste, A. Ischer, F. Parker, J. Kelly, S. Pinto, E. & Sanglard, D. (2012). Azole resistance by loss of function of the sterol  5,6-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence. Antimicrobial Agents and Chemotherapy

    https://cronfa.swan.ac.uk/Record/cronfa6836 doi:10.1128/AAC.05720-11

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