Matthew is a senior researcher and laboratory manager at the Haemostasis Biomedical Research Unit and the Welsh Institute of Emergency Biomedical Research at Swansea University. His main areas of expertise include rheometry, haemorheology, coagulation and haemostasis. Matthew’s research interests involve creating a better understand how disease and its treatment alter coagulation, clot quality and patient outcome. His work is centred on using his expertise from the physical sciences in the validation and development of new healthcare technologies for the measurement of coagulation. His research focuses on three important goals in health care 1) early detection 2) evaluation of therapeutic intervention 3) health screening. His work aims to improve the management of cardiovascular, cerebrovascular and thromboembolic disease.
 
He has also developed expertise in the field of research ethics and governance, where he is also a member of the local research ethics committee (Wales Rec 6- from 2013 to present).

Areas of Expertise

  • Rheology
  • Haemorheology
  • Research Ethics
  • Research Governance
  • Haemostasis

Publications

  1. & An Investigation Into the Effects of In Vitro Dilution With Different Colloid Resuscitation Fluids on Clot Microstructure Formation. Anesthesia & Analgesia 123(5), 1081-1088.
  2. & The effect of tyramine infusion and exercise on blood flow, coagulation and clot microstructure in healthy individuals. Thrombosis Research 170, 32-37.
  3. & The effect of sepsis and septic shock on the viscoelastic properties of clot quality and mass using rotational thromboelastometry: A prospective observational study. Journal of Critical Care 44, 7-11.
  4. & Assessment of platelet function in patients with stroke using multiple electrode platelet aggregometry: a prospective observational study. BMC Neurology 16(1)
  5. & Platelet reactivity influences clot structure as assessed by fractal analysis of viscoelastic properties. Platelets, 1-9.

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Teaching

  • PM-230 Selected Medical Diagnostic Techniques

    This module looks at the design and operation of a wide range of instrumentation used to make measurements for diagnostic and monitoring of health and disease. The emphasis is on the underlying electrical, mechanical, chemical, optical and other engineering principles together with the advantages and limitations of techniques.