Matthew is a senior researcher and laboratory manager at the Haemostasis Biomedical Research Unit and the Welsh Institute of Emergency Biomedical Research at Swansea University. His main areas of expertise include rheometry, haemorheology, coagulation and haemostasis. Matthew’s research interests involve creating a better understand how disease and its treatment alter coagulation, clot quality and patient outcome. His work is centred on using his expertise from the physical sciences in the validation and development of new healthcare technologies for the measurement of coagulation. His research focuses on three important goals in health care 1) early detection 2) evaluation of therapeutic intervention 3) health screening. His work aims to improve the management of cardiovascular, cerebrovascular and thromboembolic disease.
 
He has also developed expertise in the field of research ethics and governance, where he is also a member of the local research ethics committee (Wales Rec 6- from 2013 to present).

Areas of Expertise

  • Rheology
  • Haemorheology
  • Research Ethics
  • Research Governance
  • Haemostasis

Publications

  1. Evans, P., Potter, J., Wani, M., Evans, V., Morris, R., Sabra, A., Stanford, S., Storton, S., Lawrence, M., D’Silva, L. Assessment of platelet function in patients with stroke using multiple electrode platelet aggregometry: a prospective observational study BMC Neurology 16 1
  2. Lawrence, M. An Investigation Into the Effects of In Vitro Dilution With Different Colloid Resuscitation Fluids on Clot Microstructure Formation Anesthesia & Analgesia 123 5 1081 1088
  3. Lawrence, M., Marsden, N., Mothukuri, R., Morris, R., Davies, G., Hawkins, K., Curtis, D., Brown, M., Williams, P., Evans, P. The Effects of Temperature on Clot Microstructure and Strength in Healthy Volunteers Anesthesia & Analgesia 122 1 21 26
  4. Williams, R., Hawkins, K., Brown, R., Lawrence, M., Curtis, D., Evans, A. A new biomarker quantifies differences in clot microstructure in patients with venous thromboembolism British Journal of Haematology 168 4 571 575
  5. Sabra, A., Thomas, P., Obaid, D., D'Silva, L., Morris, R., Hawkins, K., Brown, M., Williams, P., Davidson, S., Chase, A., Lawrence, M., Smith, D., Evans, P. Fractal dimension: A novel clot microstructure biomarker use in ST elevation myocardial infarction patients Atherosclerosis 240 2 402 407

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Teaching

  • PM-230 Selected Medical Diagnostic Techniques

    This module looks at the design and operation of a wide range of instrumentation used to make measurements for diagnostic and monitoring of health and disease. The emphasis is on the underlying electrical, mechanical, chemical, optical and other engineering principles together with the advantages and limitations of techniques.