Professor Venkat Kanamarlapudi

Professor Venkat Kanamarlapudi
Professor of Molecular Cell Biology
Biomedical Sciences
Telephone: (01792) 295012
Room: Academic Office - 204
Second Floor
Institute of Life Science 1
Singleton Campus

Areas of Expertise

  • Cell Biology
  • Cell Signalling
  • Molecular Mechanisms of disease
  • Biochemistry
  • Molecular Biology
  • Diabetes
  • Cancer
  • Host pathogen interactions
  • Phagocytosis
  • Membrane trafficking
  • Drug discovery
  • Endocytosis
  • Glucagon like peptide-1 (GLP-1)
  • Arf6
  • G protein coupled receptor (GPCR)
  • Neuroscience

Publications

  1. Venkateswarlu, K., Kanamarlapudi, V. Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug FEMS Microbiology Letters 131 3 337 341
  2. Masaphy, S., Kanamarlapudi, V. Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungus Phanerochaete chrysosporium FEMS Microbiology Letters 135 1 51 55
  3. Venkateswarlu, K., Kelly, S., Kanamarlapudi, V. Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus FEMS Immunology & Medical Microbiology 16 1 11 20
  4. Cullen, P., Lockyer, P., Reynolds, J., Venkateswarlu, K., Kanamarlapudi, V. GAP1IP4BP; a protein linking inositol 1,3,4,5-tetrakisphosphate with Ras and Ca2+homeostasis Biochemical Society Transactions 25 3 507S.3 507S
  5. Lockyer, P., Bottomley, J., Reynolds, J., McNulty, T., Venkateswarlu, K., Potter, B., Dempsey, C., Cullen, P., Kanamarlapudi, V. Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting Current Biology 7 12 1007 1010

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Teaching

  • PM-304 Biomolecular Research Project

    *

  • PM-331 Membrane Trafficking

    The module provides an understanding of the subcellular organelles, the regulation of their biosynthesis and how impairment of this process leads to disease.

  • PM-334 Biochemistry Literature Review and Communication

    Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.

  • PMLM05 LC/MS Applications IV: Medical and life sciences

    Students will have the opportunity to gain extensive knowledge of the role mass spectrometry plays in biomarker discovery (proteins and small molecules).with its application to clinical diagnosis including the analysis of carbohydrates, glycoproteins and nucleic acids using activity-based proteomics and techniques for affinity pull-down.

Supervision

  • Analysis of the Effects of Mechanical Heart Pumps on Blood Components (current)

    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Venkat Kanamarlapudi
  • Enhancing osteogenic capabilities of human mesenchymal stem cells of 3D-printed hydroxyapatite/calcium carbonate scaffolds. (current)

    MSc
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr Zhidao Xia
  • Studying the underlying mechanisms of the GLP-1 receptor agonists treatment for diabesity (current)

    MSc
    Other supervisor: Prof Steve Bain
    Other supervisor: Prof Venkat Kanamarlapudi
  • Investigating a Sterol Oxidising Cytochrome P450 Present in Mycobacteroides abscessus (current)

    MSc
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Prof Diane Kelly
  • Targeting the interleukin-13 receptor (IL-13R)alpha2 expressing pancreatic cancer by a novel hybrid lytic peptide drug (current)

    PhD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Venkat Kanamarlapudi
  • Modelling and Analysing Receptor Cooperativity (current)

    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr Gibin Powathil
  • Targeting Shear-Induced von Willebrand Factor Degradation via ADAMTS13 and Platelet Damage from Ventricular Assist Devices (current)

    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Venkat Kanamarlapudi
  • Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicles Generation and their Cellular Effects (current)

    PhD
    Other supervisor: Prof Yuqin Wang
    Other supervisor: Prof Venkat Kanamarlapudi
  • Untitled (current)

    MD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Venkat Kanamarlapudi
  • Molecular mechanism of Arf6 small GTPase inhibition in treating multidrug resistant bacterial infections (current)

    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Prof Venkat Kanamarlapudi
  • Contemporary approaches to the diagnosis and management of Pancreatic Ductal Adenocarcinoma, examining the role of biomarkers in aiding early diagnosis (current)

    MD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Peter Dunstan
    Other supervisor: Prof Venkat Kanamarlapudi
  • Functional characterisation of EFA6R, a possible biomarker for Epithelial Ovarian Cancer (awarded 2019)

    PhD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Venkat Kanamarlapudi