Professor Venkat Kanamarlapudi

Professor Venkat Kanamarlapudi
Professor of Molecular Cell Biology
Medicine
Telephone: (01792) 295012
Room: Academic Office - 204
Second Floor
Institute of Life Science 1
Singleton Campus

Areas of Expertise

  • Cell Biology
  • Cell Signalling
  • Molecular Mechanisms of disease
  • Biochemistry
  • Molecular Biology
  • Diabetes
  • Cancer
  • Host pathogen interactions
  • Phagocytosis
  • Membrane trafficking
  • Drug discovery
  • Endocytosis
  • Glucagon like peptide-1 (GLP-1)
  • Arf6
  • G protein coupled receptor (GPCR)
  • Neuroscience

Publications

  1. Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug. FEMS Microbiology Letters 131(3), 337-341.
  2. Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungus Phanerochaete chrysosporium. FEMS Microbiology Letters 135(1), 51-55.
  3. & Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus. FEMS Immunology & Medical Microbiology 16(1), 11-20.
  4. & GAP1IP4BP; a protein linking inositol 1,3,4,5-tetrakisphosphate with Ras and Ca2+homeostasis. Biochemical Society Transactions 25(3), 507S.3-507S.
  5. & Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting. Current Biology 7(12), 1007-1010.

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Teaching

  • PM-304 Biomolecular Research Project

    *

  • PM-331 Membrane Trafficking

    The module provides an understanding of the subcellular organelles, the regulation of their biosynthesis and how impairment of this process leads to disease.

  • PM-334 Biochemistry Literature Review and Communication

    Students will acquire a detailed knowledge of one topical research area of key importance to their particular degree scheme.

  • PMLM05 LC/MS Applications IV: Medical and life sciences

    Students will have the opportunity to gain extensive knowledge of the role mass spectrometry plays in biomarker discovery (proteins and small molecules).with its application to clinical diagnosis including the analysis of carbohydrates, glycoproteins and nucleic acids using activity-based proteomics and techniques for affinity pull-down.

Supervision

  • Analysis of the Effects of Mechanical Heart Pumps on Blood Components (current)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Venkat Kanamarlapudi
  • Studying the underlying mechanisms of the GLP-1 receptor agonists treatment for diabesity (current)

    Student name:
    MPhil
    Other supervisor: Prof Steve Bain
    Other supervisor: Prof Venkat Kanamarlapudi
  • Untitled (current)

    Student name:
    MSc
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr Zhidao Xia
  • Investigating a Sterol Oxidising Cytochrome P450 Present in Mycobacteroides abscessus (current)

    Student name:
    MSc
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Prof Diane Kelly
  • Contemporary approaches to the diagnosis and management of Pancreatic Ductal Adenocarcinoma, examining the role of ELISA and Raman Spectroscopy in the development of reliable biomarkers to aid early diagnosis (current)

    Student name:
    MD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Peter Dunstan
    Other supervisor: Prof Venkat Kanamarlapudi
  • Targeting the interleukin-13 receptor (IL-13R)alpha2 expressing pancreatic cancer by a novel hybrid lytic peptide drug (current)

    Student name:
    PhD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Venkat Kanamarlapudi
  • Targeting Shear-Induced von Willebrand Factor Degradation via ADAMTS13 and Platelet Damage from Ventricular Assistance Devices«br /»«br /»«br /» (current)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Venkat Kanamarlapudi
  • Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicles Generation and their Cellular Effects (current)

    Student name:
    PhD
    Other supervisor: Prof Yuqin Wang
    Other supervisor: Prof Venkat Kanamarlapudi
  • Molecular mechanism of Arf6 small GTPase inhibition in treating multidrug resistant bacterial infections (current)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
    Other supervisor: Prof Venkat Kanamarlapudi
  • Modelling and Analysing Receptor Cooperativity (current)

    Student name:
    PhD
    Other supervisor: Prof Venkat Kanamarlapudi
    Other supervisor: Dr Gibin Powathil
  • Functional characterisation of EFA6R, a possible biomarker for Epithelial Ovarian Cancer (awarded 2019)

    Student name:
    PhD
    Other supervisor: Dr William Walker
    Other supervisor: Prof Venkat Kanamarlapudi