Areas of Expertise

  • Nanomedicine
  • Immunology
  • Molecular biology
  • Drug development
  • Project Management
  • Gynaecological cancer
  • Reproductive biology

Publications

  1. Healey, G., Conlan, S. Therapeutic Development and the Evolution of Precision Medicine (Ed.), Nanoscience and Nanotechnology for Human Health 359 378
  2. Howard, D., Garcia-Parra, J., Healey, G., Amakiri, C., Margarit, L., Francis, L., Gonzalez, D., Conlan, R., Conlan, S., Garcia Parra, J. Antibody–drug conjugates and other nanomedicines: the frontier of gynaecological cancer treatment Interface Focus 6 6 20160054
  3. Vitorino Carvalho, A., Reinaud, P., Forde, N., Healey, G., Eozenou, C., Giraud-delville, C., Mansouri-Attia, N., Gall, L., Richard, C., Lonergan, P., Sheldon, I., Lea, R., Sandra, O., Healey, G., Sheldon, M. SOCS genes expression during physiological and perturbed implantation in bovine endometrium Reproduction
  4. Vitorino Carvalho, A., Eozenou, C., Healey, G., Forde, N., Reinaud, P., Chebrout, M., Gall, L., Rodde, N., Padilla, A., Delville, C., Leveugle, M., Richard, C., Sheldon, I., Lonergan, P., Jolivet, G., Sandra, O., Healey, G., Sheldon, M. Analysis of STAT1 expression and biological activity reveals interferon-tau-dependent STAT1-regulated SOCS genes in the bovine endometrium Reproduction, Fertility and Development
  5. Healey, G., Zinnen, S., Lockridge, J., Richards, I., Evans, N., Walker, W. Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: characterisation and selection of candidates for pre-clinical development Journal of RNAi and Gene Silencing 6 2 401 410

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Teaching

  • PMNM04 Nanomedicines and Therapeutics

    The module will explore the history and development of molecular medicines. Using landmark technology and chemical development phases, the traditional small chemical entities using in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. The common target oncology and non oncology disorders will outlined and their respective targets for such medicines detailed alongside drug modes of action and delivery (IV and oral). Further exploration of targeted nanoparticle delivery, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems, will expand the knowledge to future molecular medicines such as antibody drug conjugates and kinase inhibitors. Excitingly the module will include guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.

  • PMNM11 Nanomedicines, pharmaceuticals and advanced therapeutics

    This module will explore the history and development of molecular medicines and pharmaceuticals, providing the basis for an advanced understanding of next generation therapeutic approaches. Using landmark technology and chemical development phases informed by separation science and mass spectrometry, the module uses an application driven approach to provide the student with an extensive knowledgebase of drug development, the pharmaceutical industry and nanotherapeutics. Students will be able to characterize and map the path of a drug from administration, to metabolism and elimination, and critically evaluate drug design and delivery approaches. Traditional small chemical entities used in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. Common target oncology and non-oncology disorders will provide the context; with students encouraged to explore targeted nanoparticle fabrication, drug encapsulation and release profiling, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems. Future molecular medicines such as antibody drug conjugates and kinase inhibitors will be taught by guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.

Research Groups

  • Reproductive Biology and Gynaecological Oncology

    Reproductive biology and gynaecological oncology research in Swansea covers basic and translational research into: Uterine pathologies, Gynaecological and in vitro fertilisation

Key Grants and Projects

  • CALIN (Celtic Advanced Life Science Innovation Network) 2016

    Project Manager