Professor Steve Bain
Professor in Medicine(Diabetes)
Medicine
Telephone: (01792) 602205
Room: Office - 123
Ground Floor
Grove Building
Singleton Campus

Professor Steve Bain is Assistant Medical Director for Research & Development for ABM University Health Board and Clinical Lead for the Diabetes Research Network, Wales.
After undergraduate training at St John's College, Cambridge, he was clinically trained at King's College Hospital, London. Qualifying in 1983, he held junior appointments in London, East Midlands, and West Midlands. His research centred on the genetics of type 1 diabetes, and he was granted a Medical Research Council Lecturership. In 1993, he became a Senior Lecturer/Honorary Consultant Physician at Birmingham Heartlands Hospital, with promotion to Reader in Diabetic Medicine in 1998. Professor Bain became a Fellow of the Royal College of Physicians, UK, in 1996 and was appointed to a newly created Chair in Medicine (Diabetes) at Swansea University in 2005. His clinical interests include the genetics of diabetic nephropathy, new therapies for diabetes and the provision of diabetes services within the community. He has been Principal Investigator for several multi-centre trials investigating novel therapies for diabetes.
As a result of his genetics background, Professor Bain became a member of the inaugural West Midlands Multicentre Research Ethics Committee (MREC) and joined the UK Human Genetics Commission. From 2003-2008 he was HGC’s nomination on the National DNA Database Strategy Board and led the HGC report on DNA testing in 2009. In 2007 he was invited to sit on the newly formed National DNA Database Ethics Group, established by the Secretary of State for the Home Department. Professor Bain is Diabetes Lead Clinician for ABM University Health Board, a member of the Wales Diabetes & Endocrine Society (WEDS) executive committee and chairs the Specialist Training Committee for Diabetes & Endocrinology for Wales. He is also on the Board which oversees the ILS Joint Clinical Research Facility, the premier clinical research institute in Wales and is Clinical Director of the Academic Health Science Collaboration for Wales.

Areas of Expertise

  • R&D

Publications

  1. Bain, S. Impact of baseline characteristics and beta‐cell function on the efficacy and safety of subcutaneous once‐weekly semaglutide: a patient‐level, pooled analysis of the SUSTAIN 1–5 trials Diabetes, Obesity and Metabolism
  2. Bain, S. Pharmacological treatment for Type 2 diabetes integrating findings from cardiovascular outcome trials: an expert consensus in the UK Diabetic Medicine 36 9 1063 1071
  3. Bain, S. SGLT2 Inhibitors: Cardiovascular Benefits Beyond HbA1c—Translating Evidence into Practice Diabetes Therapy 1 28
  4. Bain, S. Evaluating the burden of poor glycemic control associated with therapeutic inertia in patients with type 2 diabetes in the UK Journal of Medical Economics 1 8
  5. Bain, S. Effect of liraglutide on occurrence of total (first and recurrent) major cardiovascular events in the LEADER cardiovascular outcomes trial JAMA Cardiology

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Teaching

  • PM-356 The Sweet Sickness: Advances in Diabetes and Related Disorders

    7% of the population suffers from diabetes. This prevalence is set to rise with an ageing population and increasing rates of obesity. The problem is especially acute in Wales, where over half the adult population is obese. According to Diabetes Wales, there are 177,000 people in the country living with diabetes, and estimates suggest a further 70,000 people have diabetes but are either unaware or have no confirmed diagnosis. If current trends continue, by 2025, it is estimated that 300,000 people in Wales will have diabetes. This module will provide an overview of diabetes and the public health challenges it presents. The world-leading research of the Diabetes Research Unit Cymru, located here at Swansea University Medical School, will be a particular focus with basic, clinical, epidemiological, social care and health services research discussed.

  • PMDM01 Diabetes Basics

    This core module aims to introduce the basics of diabetes, a condition where there are an estimated 4.5 million people living with the disease in the UK alone, and a further 1.1 million that are undiagnosed. It will detail prevalence and pathophysiology, nutrition and self-care, and a basic understanding of associated complications. It aims to develop the students¿ knowledge of the many key factors that contribute to this enormous healthcare issue. The module will be delivered online via distance learning, with online assessments.

  • PMDM05 Diabetes Management II

    This core module is delivered primarily as a 5-day residential that aims to enhance the students¿ knowledge of the advanced treatments for diabetes. It will explore continuous/flash glucose monitoring and all aspects of pump technologies and pregnancy usage. This will enable the students to see and handle these new technologies that are not necessarily common place in clinics, and appreciate the concept of treatment planning and progression using these devices. The module will be delivered primarily on campus (5-day residential) with extra online content, and both in situ and online assessments.

  • PMDM101 Diabetic Practice

    Diabetes has reached world wide epidemic proportions and is fast becoming the defining disease of the 21st century. It also represents a major challenge to health organizations in chronic disease management. This module provides the basis for health care professionals to deliver high quality multidisciplinary diabetes care is an accredited qualification in Diabetes Care from the Swansea University. The module enables students to extend their network of contacts with others working in diabetes care, share experiences and develop supportive relationships.

  • PMZM17 Diabetes Management II

    This core module is delivered as a 5-day residential that aims to enhance the students¿ knowledge of the advanced treatments for diabetes. It will explore continuous/flash glucose monitoring and all aspects of pump technologies and pregnancy usage. This will enable the students to see and handle these new technologies that are not necessarily common place in clinics, and appreciate the concept of treatment planning and progression using these devices. This module will be delivered through via a 5 day residential.

  • PMZM18 Diabetic Practice

    Diabetes has reached world wide epidemic proportions and is fast becoming the defining disease of the 21st century. It also represents a major challenge to health organizations in chronic disease management. This module provides the basis for health care professionals to deliver high quality multidisciplinary diabetes care is an accredited qualification in Diabetes Care from the Swansea University. The module enables students to extend their network of contacts with others working in diabetes care, share experiences and develop supportive relationships.

Supervision

  • Provisional Title: Influence of adjusting rapid-acting insulin aspart on post-exercise nocturnal hypoglycaemia in recreationally active people with type 1 diabetes on insulin degludec (current)

    Student name:
    PhD
    Other supervisor: Dr Richard Bracken
  • Studying the underlying mechanisms of the GLP-1 receptor agonists treatment for diabesity (current)

    Student name:
    MPhil
    Other supervisor: Prof Venkat Kanamarlapudi
  • Acute Kidney Injury in Wales (current)

    Student name:
    MD
    Other supervisor: Prof Ronan Lyons
  • Biobanking neurological conditions in Wales for Genetic Research (current)

    Student name:
    PhD
    Other supervisor: Dr Owain Howell
  • The use of Proinsulin in identification of glucose intolerance (current)

    Student name:
    PhD
    Other supervisor: Prof Stephen Luzio
  • Interstitial glucose monitoring around sustained moderate intensity exercse in individuals with type 1 diabetes (awarded 2018)

    Student name:
    MSc
    Other supervisor: Dr Richard Bracken
  • 'Temporal Effects of Bariatric Surgery on Cardiovascular Risk, Glucose Metabolism and Inflammation at 5 years Follow-Up' (awarded 2018)

    Student name:
    MD
    Other supervisor: Prof Jeffrey Stephens