Publications

Journal Articles

  1. Jones, R., Velasco, M., Harris, L., Morgan, S., Temple, M., Ruddy, M., Williams, R., Perry, M., Hitchings, M., Wilkinson, T., Humphrey, T., Gilbert, M., Davies, A. Resolving a clinical tuberculosis outbreak using palaeogenomic genome reconstruction methodologies Tuberculosis 119 101865
  2. Pascoe, B., Williams, L., Calland, J., Meric, G., Hitchings, M., Dyer, M., Ryder, J., Shaw, S., Lopes, B., Chintoan-Uta, C., Allan, E., Vidal, A., Fearnley, C., Everest, P., Pachebat, J., Cogan, T., Stevens, M., Humphrey, T., Wilkinson, T., Cody, A., Colles, F., Jolley, K., Maiden, M., Strachan, N., Pearson, B., Linton, D., Wren, B., Parkhill, J., Kelly, D., van Vliet, A., Forbes, K., Sheppard, S. Domestication of Campylobacter jejuni NCTC 11168 Microbial Genomics 5 7
  3. Humphrey, T., Wilkinson, T., Cody, A., Colles, F., Jolley, K., Maiden, M., Wren, B., Pearson, B., Linton, D., Stevens, M., Parkhill, J., Kelly, D., Vliet, A., Strachan, N., Cogan, T., Fearnley, C., Everest, P., Forbes, K., Vidal, A., Allan, E., Chintoan-Uta, C., Lopes, B., Shaw, S., Ryder, J., Dyer, M., Hitchings, M., Méric, G., Calland, J., Williams, L., Pascoe, B., Pachebat, J., Sheppard, S. Domestication of Campylobacter jejuni NCTC 11168 Microbial Genomics 5 7
  4. Evans, S., Clift, M., Singh, N., Wills, J., Hondow, N., Wilkinson, T., Burgum, M., Brown, A., Jenkins, G., Doak, S. In vitro detection of in vitro secondary mechanisms of genotoxicity induced by engineered nanomaterials Particle and Fibre Toxicology 16 1
  5. Sandilands, V., Whyte, F., Williams, L., Wilkinson, T., Sparks, N., Humphrey, T., Wilkinson, T., Williams, L. Reliably colonising broiler chickens with Campylobacter spp. using a litter-based method British Poultry Science 1 5
  6. Wilkinson, T., Jenkins, G., Davies, A., Row, P., Hitchings, M., Islam, S. Protocol for faecal microbiota transplantation in ulcerative colitis (FMTUC): a randomised feasibility study BMJ Open
  7. Berthenet, E., Yahara, K., Thorell, K., Pascoe, B., Meric, G., Mikhail, J., Engstrand, L., Enroth, H., Burette, A., Megraud, F., Varon, C., Atherton, J., Smith, S., Wilkinson, T., Hitchings, M., Falush, D., Sheppard, S. A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk BMC Biology 16 1
  8. Evans, S., Clift, M., Singh, N., De Oliveira Mallia, J., Burgum, M., Wills, J., Wilkinson, T., Jenkins, G., Doak, S., Jenkins, G., Wilkinson, T., Clift, M. Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity Mutagenesis 32 1 233 241
  9. Harris, L., Dudley, E., Rohde, H., Frommelt, L., Siemssen, N., Wilkinson, T., Mack, D. Limitations in the use of PSMγ, agr , RNAIII, and biofilm formation as biomarkers to define invasive Staphylococcus epidermidis from chronic biomedical device-associated infections International Journal of Medical Microbiology 307 7 382 387
  10. John, D., Williams, L., Kanamarlapudi, V., Humphrey, T., Wilkinson, T. The Bacterial Species Campylobacter jejuni Induce Diverse Innate Immune Responses in Human and Avian Intestinal Epithelial Cells Frontiers in Microbiology 8
  11. Murray, S., Pascoe, B., Méric, G., Mageiros, L., Yahara, K., Hitchings, M., Friedmann, Y., Wilkinson, T., Gormley, F., Mack, D., Bray, J., Lamble, S., Bowden, R., Jolley, K., Maiden, M., Wendlandt, S., Schwarz, S., Corander, J., Fitzgerald, J., Sheppard, S. Recombination-Mediated Host Adaptation by Avian Staphylococcus aureus Genome Biology and Evolution 9 4 830 842
  12. Harris, L., Murray, S., Pascoe, B., Bray, J., Meric, G., Mageiros, L., Wilkinson, T., Jeeves, R., Rohde, H., Schwarz, S., de Lencastre, H., Miragaia, M., Rolo, J., Bowden, R., Jolley, K., Maiden, M., Mack, D., Sheppard, S. Correction: Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples PLOS ONE 11 4 e0154510
  13. Harris, L., Murray, S., Pascoe, B., Bray, J., Meric, G., Magerios, L., Wilkinson, T., Jeeves, R., Rohde, H., Schwarz, S., de Lencastre, H., Miragaia, M., Rolo, J., Bowden, R., Jolley, K., Maiden, M., Mack, D., Sheppard, S. Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples PLOS ONE 11 3 e0151240
  14. AL-Ishaq, R., Armstrong, J., Gregory, M., O’Hara, M., Phiri, K., Harris, L., Rohde, H., Siemssen, N., Frommelt, L., Mack, D., Wilkinson, T. Effects of polysaccharide intercellular adhesin (PIA) in an ex vivo model of whole blood killing and in prosthetic joint infection (PJI): A role for C5a International Journal of Medical Microbiology
  15. Al-Ali, A., Singh, N., Manshian, B., Wilkinson, T., Wills, J., Jenkins, G., Doak, S., Wilkinson, T. Quantum dot induced cellular perturbations involving varying toxicity pathways Toxicol. Res.
  16. Méric, G., Miragaia, M., de Been, M., Yahara, K., Pascoe, B., Mageiros, L., Mikhail, J., Harris, L., Wilkinson, T., Rolo, J., Lamble, S., Bray, J., Jolley, K., Hanage, W., Bowden, R., Maiden, M., Mack, D., de Lencastre, H., Feil, E., Corander, J., Sheppard, S., Meric, G. Ecological Overlap and Horizontal Gene Transfer in Staphylococcus aureus and Staphylococcus epidermidis Genome Biology and Evolution 7 5 1313 1328
  17. Moncayo-Nieto, O., Wilkinson, T., Brittan, M., McHugh, B., Jones, R., Conway Morris, A., Walker, W., Davidson, D., Simpson, A. Differential response to bacteria, and TOLLIP expression, in the human respiratory tract BMJ Open Respiratory Research 1 1 e000046
  18. Pascoe, B., Dams, L., Wilkinson, T., Harris, L., Bodger, O., Mack, D., Davies, A. Dormant Cells of Staphylococcus aureus Are Resuscitated by Spent Culture Supernatant PLoS ONE 9 2 e85998
  19. Conway Morris, A., Anderson, N., Brittan, M., Wilkinson, T., McAuley, D., Antonelli, J., McCulloch, C., Barr, L., Dhaliwal, K., Jones, R., Haslett, C., Hay, A., Swann, D., Laurenson, I., Davidson, D., Rossi, A., Walsh, T., Simpson, A., Wilkinson, T. Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients British Journal of Anaesthesia 111 5 778 787
  20. Morris, A., Wilkinson, T., Walsh, T., Simpson, A., Wilkinson, T. Comment on "Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans" The Journal of Immunology 191 10 4893 4893
  21. Wilkinson, T., Conway Morris, A., Kefala, K., O'Kane, C., Moore, N., Booth, N., McAuley, D., Dhaliwal, K., Walsh, T., Haslett, C., Sallenave, J., Simpson, A., Wilkinson, T. Ventilator-Associated Pneumonia Is Characterized by Excessive Release of Neutrophil Proteases in the Lung Chest 142 6 1425 1432
  22. Dhaliwal, K., Scholefield, E., Ferenbach, D., Gibbons, M., Duffin, R., Dorward, D., Morris, A., Humphries, D., MacKinnon, A., Wilkinson, T., Wallace, W., Van Rooijen, N., Mack, M., Rossi, A., Davidson, D., Hirani, N., Hughes, J., Haslett, C., Simpson, A., Wilkinson, T. Monocytes Control Second-Phase Neutrophil Emigration in Established Lipopolysaccharide-induced Murine Lung Injury American Journal of Respiratory and Critical Care Medicine 186 6 514 524
  23. Almarashi, J., Kapel, N., Wilkinson, T., Telle, H. Raman Spectroscopy of Bacterial Species and Strains Cultivated under Reproducible Conditions Spectroscopy: An International Journal 27 5-6 365
  24. Wilkinson, T. Monocytes control second-phase neutrophil emigration in established LPS-induced murine injury Am J Respir Crit Care Med 186 6 514 524
  25. Spiliopoulou, A., Kolonitsiou, F., Krevvata, M., Leontsinidis, M., Wilkinson, T., Mack, D., Anastassiou, E., Wilkinson, T. Bacterial adhesion, intracellular survival and cytokine induction upon stimulation of mononuclear cells with planktonic or biofilm phase Staphylococcus epidermidis FEMS Microbiology Letters 330 1 56 65
  26. Spiliopoulou, A., Krevvata, M., Kolonitsiou, F., Harris, L., Wilkinson, T., Davies, A., Dimitracopoulos, G., Karamanos, N., Mack, D., Anastassiou, E. An extracellular Staphylococcus epidermidis polysaccharide: relation to Polysaccharide Intercellular Adhesin and its implication in phagocytosis BMC Microbiology 12 1 76
  27. Morris, A., Brittan, M., Wilkinson, T., McAuley, D., Antonelli, J., McCulloch, C., Barr, L., McDonald, N., Dhaliwal, K., Jones, R., Mackellar, A., Haslett, C., Hay, A., Swann, D., Anderson, N., Laurenson, I., Davidson, D., Rossi, A., Walsh, T., Simpson, A., Wilkinson, T. C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients Blood 117 19 5178 5188
  28. Wilkinson, T., Roghanian, A., Simpson, A., Wilkinson, T. WAP domain proteins as modulators of mucosal immunity Biochem Soc Trans 39 1409 1415
  29. Murray, M., Govan, J., Doherty, C., Simpson, A., Wilkinson, T., Chalmers, J., Greening, A., Haslett, C., Hill, A. A Randomized Controlled Trial of Nebulized Gentamicin in Non–Cystic Fibrosis Bronchiectasis American Journal of Respiratory and Critical Care Medicine 183 4 491 499
  30. Barlow, P., Beaumont, P., Cosseau, C., Mackellar, A., Wilkinson, T., Hancock, R., Haslett, C., Govan, J., Simpson, A., Davidson, D., Wilkinson, T. The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium American Journal of Respiratory Cell and Molecular Biology 43 6 692 702
  31. Potter-Perigo, S., Johnson, P., Evanko, S., Chan, C., Braun, K., Wilkinson, T., Altman, L., Wight, T., Wilkinson, T. Polyinosine-Polycytidylic Acid Stimulates Versican Accumulation in the Extracellular Matrix Promoting Monocyte Adhesion American Journal of Respiratory Cell and Molecular Biology 43 1 109 120
  32. Fox, S., Wilkinson, T., Wheatley, P., Xiao, B., Morris, R., Sutherland, A., Simpson, A., Barlow, P., Butler, A., Megson, I., Rossi, A., Wilkinson, T. NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy Acta Biomaterialia 6 4 1515 1521
  33. Conway Morris, A., Kefala, K., Wilkinson, T., Wilkinson, T. Correction Thorax 65 9 844 844
  34. Fox, S., Wilkinson, T., Wheatley, P., Wilkinson, T. NO-loaded Zn2+-Exchanged Zeolite Materials; A Potential Bi-Functional Anti-Bacterial Strategy Acta Biomaterialia 692 702
  35. Conway Morris, A., Kefala, K., Wilkinson, T., Dhaliwal, K., Farrell, L., Walsh, T., Mackenzie, S, J., Reid, H., Davidson, D., Haslett, C., Rossi, A., J-M, S., Simpson, A., Wilkinson, T. C5a mediates peripheral blood neutrophil dysfunction in critically ill patients American Journal of Respiratory and Critical Care Medicine 180 1 19 28
  36. Marriott, H., Jackson, L., Wilkinson, T., Simpson, A., Mitchell, T., Buttle, D., Cross, S., Ince, P., Hellewell, P., Whyte, M., Dockrell, D. Reactive Oxygen Species Regulate Neutrophil Recruitment and Survival in Pneumococcal Pneumonia American Journal of Respiratory and Critical Care Medicine 177 8 887 895
  37. Farnworth, S., Henderson, N., Mackinnon, A., Atkinson, K., Wilkinson, T., Dhaliwal, K., Hayashi, K., Simpson, A., Rossi, A., Haslett, C., Sethi, T., Wilkinson, T. Galectin-3 Reduces the Severity of Pneumococcal Pneumonia by Augmenting Neutrophil Function The American Journal of Pathology 172 2 395 405
  38. Barlow, P., Li, Y., Wilkinson, T., Bowdish, D., Lau, Y., Cosseau, C., Haslett, C., Simpson, A., Hancock, R., Davidson, D., Wilkinson, T. The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system Journal of Leukocyte Biology 80 3 509 520
  39. Wilkinson, T., Bressler, S., Evanko, S., Braun, K., Wight, T., Wilkinson, T. Overexpression of hyaluronan synthases alters vascular smooth muscle cell phenotype and promotes monocyte adhesion Journal of Cellular Physiology 206 2 378 385
  40. Wilkinson, T., Potter-Perigo, S., Tsoi, C., Altman, L., Wight, T., Wilkinson, T. Pro- and Anti-Inflammatory Factors Cooperate to Control Hyaluronan Synthesis in Lung Fibroblasts American Journal of Respiratory Cell and Molecular Biology 31 1 92 99
  41. McLoughlin, R., Hurst, S., Nowell, M., Harris, D., Horiuchi, S., Morgan, L., Wilkinson, T., Yamamoto, N., Topley, N., Jones, S., Wilkinson, T. Differential Regulation of Neutrophil-Activating Chemokines by IL-6 and Its Soluble Receptor Isoforms The Journal of Immunology 172 9 5676 5683
  42. McLoughlin, R., Witowski, J., Robson, R., Wilkinson, T., Hurst, S., Williams, A., Williams, J., Rose-John, S., Jones, S., Topley, N., Wilkinson, T. Interplay between IFN-γ and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation Journal of Clinical Investigation 112 4 598 607
  43. Hurst, S., Wilkinson, T., McLoughlin, R., Jones, S., Horiuchi, S., Yamamoto, N., Rose-John, S., Fuller, G., Topley, N., Jones, S., Wilkinson, T. IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation Immunity 14 6 705 714
  44. Robson, R., McLoughlin, R., Witowski, J., Loetscher, P., Wilkinson, T., Jones, S., Topley, N., Wilkinson, T. Differential Regulation of Chemokine Production in Human Peritoneal Mesothelial Cells: IFN-  Controls Neutrophil Migration Across the Mesothelium In Vitro and In Vivo The Journal of Immunology 167 2 1028 1038
  45. Davenport, A., Li, F., Robson, R., Wilkinson, T., McLoughlin, R., Topley, N., Wilkinson, T. Early peritoneal responses to bacterial invasion: Cellular exudation Sepsis 3 4 303 309

Books

  1. Mack, D., Davies, A., Harris, L., Jeeves, R., Pascoe, B., Knobloch, J., Rohde, H., Wilkinson, T., Wilkinson, T. Biomaterials Associated Infection