My Current Main Research Interests:

Causes of genetic diversity in natural populations

Proteomics and transcriptomics with emphasis on data analysis methods

Causes and consequences of paternal inheritance of mitochondrial DNA

Evolutionary genetic modelling of plankton populations

Comparative protein modelling and applications in evolutionary biology and medicine

See my LinkedIn and ResearchGate pages (links under my photo) for further information about me.

Areas of Expertise

  • In Research:
  • Genetics and Evolution
  • Molecular Population Genetics
  • Biological Statistics and Modelling
  • Genomics and Bioinformatics

Publications

  1. Flynn, K., Skibinski, D., Lindemann, C. Effects of growth rate, cell size, motion, and elemental stoichiometry on nutrient transport kinetics PLOS Computational Biology 14 4 e1006118
  2. Romero, M., Pérez-Figueroa, A., Carrera, M., Swanson, W., Skibinski, D., Diz, A. RNA-seq coupled to proteomic analysis reveals high sperm proteome variation between two closely related marine mussel species Journal of Proteomics
  3. Diz, A., Carvajal-Rodriguez, A., Skibinski, D., Skibinski, D. Multiple Hypothesis Testing in Proteomics: A Strategy for Experimental Work Molecular & Cellular Proteomics 10 3 M110.004374 M110.004374
  4. Diz, A., Truebano, M., Skibinski, D. The consequences of sample pooling in proteomics: An empirical study ELECTROPHORESIS 30 17 2967 2975
  5. Diz, A., Dudley, E., Cogswell, A., MacDonald, B., Kenchington, E., Zouros, E., Skibinski, D. Proteomic Analysis of Eggs fromMytilus edulisFemales Differing in Mitochondrial DNA Transmission Mode Molecular & Cellular Proteomics 12 11 3068 3080
  6. Skibinski, D., Ghiselli, F., Diz, A., Milani, L., Mullins, J. Structure-Related Differences between Cytochrome Oxidase I Proteins in a Stable Heteroplasmic Mitochondrial System Genome Biology and Evolution 9 12 3265 3281
  7. Tolman, D., Wood, H., Skibinski, D., Truebano, M. Differential immunity as a factor influencing mussel hybrid zone structure Marine Biology 166 12
  8. Diz, A., Dudley, E., MacDonald, B., Pina, B., Kenchington, E., Zouros, E., Skibinski, D., Skibinski, D., Dudley, E. Genetic Variation Underlying Protein Expression in Eggs of the Marine Mussel Mytilus edulis Molecular & Cellular Proteomics 8 132 144
  9. Mitchell, I., Skibinski, D. Analysis of Genotoxicity Data in a Regulatory Context (Ed.), 399 417
  10. Diz, A., Dudley, E., Skibinski, D. Identification and characterisation of highly expressed proteins in sperm cells of the marine mussel Mytilus edulis PROTEOMICS 12 12 1949 1956
  11. Hayward, P., Porter, J., Skibinski, D., Skibinski, D. Bayesian phylogenetics of Bryozoa MOLECULAR PHYLOGENETICS AND EVOLUTION 52 904 910
  12. Diz, A., Romero, M., Pérez-Figueroa, A., Swanson, W., Skibinski, D. RNA-seq data from mature male gonads of marine mussels Mytilus edulis and M. galloprovincialis Data in Brief 21 167 175
  13. Zbawicka, M., Burzynski, A., Skibinski, D., Skibinski, D. Scottish Mytilus trossulus mussels retain ancestral mitochondrial DNA: Complete sequences of male and female mtDNA genomes GENE 456 45 53
  14. Flynn, K., St John, M., Raven, J., Skibinski, D., Allen, J., Mitra, A., Hofmann, E. Acclimation, adaptation, traits and trade-offs in plankton functional type models: reconciling terminology for biology and modelling Journal of Plankton Research 37 4 683 691
  15. Jones, N., Piasecka, J., Bryant, A., Jones, R., Skibinski, D., Francis, N., Thornton, C., Skibinski, D., Jones, R., Thornton, C., Bryant, A., Jones, N. Bioenergetic analysis of human peripheral blood mononuclear cells Clinical & Experimental Immunology 182 1 69 80

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Teaching

  • PM-402 Advanced Research Project B

    The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an 9-month period. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-402 comprises the final written dissertation.

  • PMGM11 Introduction to Human Genetics and Genomics

    The Introduction to Human Genetics and Genomics module is a subject-specific module in the MSc Genomic Medicine programme. This unit will provide essential and contemporary knowledge relating to genetic science and genetic disease. The module will prepare participants to understand disease genetics, how genomic medicine can be utilised to elucidate disease mechanisms and biology in the context of genomic medicine. It will provide core knowledge underpinning later modules in bioinformatics and statistics. This module will serve as a foundation for those wishing to advance their careers within the NHS in genomic medicine.

Supervision

  • The development and evaluation of a computer-based tool for assessing web-based information on medicines. (awarded 2019)

    Student name:
    PhD
    Other supervisor: Prof Kerina Jones
    Other supervisor: Prof Gareth Jenkins
    Other supervisor: Prof David Skibinski
    Other supervisor: Prof David Skibinski

Administrative Responsibilities

  • Deputy Head - College of Medicine

    2010 - 2013

  • Programme Director BSc Degrees in Biochemistry and Genetics

    2006 - 2013