Dr Colin Restall
Associate Professor
Telephone: (01792) 295571
Room: Office - 256
First Floor
Grove Building
Singleton Campus

Dr Colin Restall is an Associate Professor on our Biochemistry Degrees

Areas of Expertise

  • Biochemistry and Biophysics of Biological Membranes
  • Optical Spectroscopy


  1. & Negatively-Marked MCQ Assessments That Reward Partial Knowledge Do Not Introduce Gender Bias Yet Increase Student Performance and Satisfaction and Reduce Anxiety.. PLoS ONE 8(2)
  2. & Steroid hormone-induced effects on membrane fluidity and their potential roles in non-genomic mechanisms.. Life Sciences 67, 743-757.
  3. & Developmental and neurochemical effects of early postnatal exposure to flumazenil in female and male mice.. Psicothema 12, 648-653.
  4. & Changes in the neural membranes of mice related to steroid hormone influences.. Pharmacology, Biochemistry and Behaviour. 59, 829-833.
  5. & Characterisation of the binding of leukotriene B-4 to macrophages of the rainbow trout Oncorhynchus mykiss.. J. Exp. Biol. 200, 155-160.

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  • PM-127 Energy and Metabolism: The Reactions of Life

    This module begins with an introduction to enzymology, enzyme kinetics and enzyme regulation. Next there is an introduction to bioenergetics and a discussion of the central metabolic pathways by which energy from food is used to fuel the synthesis of the energy currency molecule ATP (with particular attention to glycolysis, the citric acid cycle, ß oxidation of fatty acids, and oxidative phosphorylation). The concept of tissue and organ specificity is introduced, and finally the role of the hormones insulin, glucagon, epinephrine, growth hormone, thyroid hormone and leptin in controlling these pathways and producing effects on the body is considered.

  • PM-130 Biochemistry Skills Development

    This module is designed to develop the skills required for students of biochemistry and medical biochemistry. Students meet with their tutors and will be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint session cover generic skills such as internet searching for scientific sources, referencing and plagiarism

  • PM-131 Chemistry of Life

    The module provides a broad study of the interactions between chemical processes and biological systems. It addresses the chemical processes used by organisms to utilize chemicals for energy production, structural functions and as building blocks of macromolecules.

  • PM-243 Clinical Biochemistry & Physiology

    The module begins with a discussion of selected metabolic disorders of carbohydrate metabolism and their pathological consequences with particular emphasis on diabetes mellitus. The molecular mechanisms underlying polycystic ovarian syndrome are then considered. This is followed by a consideration of the biochemical basis of haemostasis and blood clot lysis. Next there is a discussion of inborn errors of metabolism, and the biochemical pathways affected. Finally the module reviews mechanisms of protein transport and their relevance to storage diseases.

  • PM-248 Amino acids, lipids and steroids

    The module reviews the pathways of fatty acid degradation (beta-oxidation) before describing the biochemistry of the multi-functional proteins that catalyse the formation of fatty acids. The mechanisms of fatty acid elongation and desaturation are covered along with the synthesis of triacylglycerols and glycerophospholipids with consideration being being given to the control of these pathways. The synthesis of cholesterol via the mevalonate pathway is described along with the various metabolic control points and an understanding of dietary lipid transport. The further metabolism of cholesterol to bile salts, steroid hormones and vitamin D is outlined with consideration given to the stereochemistry of these compounds. The module provides a sound basis for understanding the metabolism of amino acids, lipids and steroids. The pathways of amino acid synthesis and degradation in humans are described along with an introduction to the urea cycle.

  • PM-319 Membranes and Energy Transduction

    The module provides an understanding of the dynamic structure and properties of biological membranes and the nature of lipid-lipid and lipid-protein interactions. An appreciation of the molecular architecture of energy-conserving membranes is also provided together with an understanding of the molecular mechanisms involved in energy transduction.

Administrative Responsibilities

  • Associate Dean of Undergraduate Studies - Medicine

    2011 - Present