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Owen is a consultant neurologist and senior lecturer at Swansea University Medical School. He practices clinically as a neurologist in Swansea Bay University Health board with a sub-speciality interest in epilepsy. His research interests include epilepsy genetics, using routinely collected data for neurology research, using natural language processing as a clinical and research tool and clinical neurology research.


Mae Owen yn ymgynghorydd niwrolegol ac uwch darllithydd yn Ysgol Feddygaeth Prifysgol Abertawe. Mae’n gweithio yn glinigol fel ymgynghorydd niwrolegol ym Mwrdd Iechyd Prifysgol Bae Abertawe ac mae ganddo ddiddordeb is-arbenigol mewn epilepsi. Mae ei ddiddordebau ymchwil yn cynnwys geneteg epilepsi, defnyddio data a gesglir fel mater o drefn ar gyfer ymchwil niwroleg, defnyddio prosesu iaith naturiol fel offeryn clinigol ac ymchwil, ac ymchwil niwroleg glinigol.

Areas of Expertise

  • epilepsy
  • genetics
  • next generation sequencing
  • natural language processing
  • routinely collected healthcare data

Publications

  1. & SUDEP and mortality in epilepsy: The role of routinely collected healthcare data, registries, and health inequalities. Epilepsy & Behavior, 106453
  2. et. al. Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals. The American Journal of Human Genetics 105(2), 267-282.
  3. & Using natural language processing to extract structured epilepsy data from unstructured clinic letters: development and validation of the ExECT (extraction of epilepsy clinical text) system. BMJ Open 9(4), e023232
  4. & Risk factors for self-harm in people with epilepsy. Journal of Neurology
  5. & New treatments in Alzheimer’s disease. Journal of Neurology 265(9), 2162-2163.

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Teaching

  • PM-257 Neuroscience

    In order to help students understand the biological basis for behavioural neuroscience and neurological disorders, this module seeks to integrate the multidisciplinary sciences - for example, anatomy, physiology and biochemistry - that have combined to build the emerging field of neuroscience. The aim is to gain a mechanistic and holistic knowledge of the nervous system that builds from the molecular, cellular and developmental, to the systems level. In addition to exploring normal function, this module will introduce common disorders of the central and peripheral nervous systems in an integrated way. Students will be guided in exploring the scientific evidence around what is known and unknown and will be introduced to current research findings in the scientific literature.

  • PM-267 Genes on Drugs: Pharmacogenomics

    Genes affect how the body reacts to drugs as well as how they are absorbed, metabolized and eliminated. You will learn how variation in genes encoding proteins involved in these processes affect how drugs work ¿ or don¿t ¿ therapeutically. By understanding these factors, you will gain insight into the emerging field of personalized medicine and learn how individualized drug design and selection can improve therapeutic efficacy, safety and sustainability.

  • PM-300 Medical Genetics

    The course is designed to provide an advanced study of the identification of human genes and the determination of the influence of human genes upon disease and health status. Gene identification provides targets for the development of new pharmaceuticals and the range of variation present in the population.