Moller, M.Gravenor, M.Roberts, S.Sun, D.Gao, P. & Hopkin, J. (2007). Genetic haplotypes of Th-2 immune signalling link allergy to enhanced protection to parasitic worms. Human Molecular Genetics 16(15), 1828-1836.
Arima, K.Umeshita-Suyama, R.Sakata, Y.Akaiwa, M.Mao, X.Enomoto, T.Dake, Y.Shimazu, S.Yamashita, T.Sugawara, N.Brodeur, S.Geha, R.Puri, R.Sayegh, M.Adra, C.Hamasaki, N.Hopkin, J.Shirakawa, T. & Izuhara, K. (2002). Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma. Journal of Allergy and Clinical Immunology 109(6), 980-987.
PMGM16Genomics of Common and Rare Inherited Disease
This module will provide an introduction to the clinical presentation and manifestations of rare inherited and common diseases, and considers the patient and family perspective with respect to the role and impact of genomics. It reviews traditional and current strategies and techniques used to identify genes responsible for both common multifactorial and rare inherited diseases.