Professor
Medicine
Telephone: (01792) 295058
Room: Office - 210
Second Floor
Institute of Life Science 2
Singleton Campus

Karl's research interests include the development of advanced rheological techniques for the characterisation of the structure and mechanical properties of biopolymer gelling systems including gelatin, collagen, fibrin and blood.  He is author of over 50 publications in international peer reviewed journals in the fields of fluid mechanics, medical devices and haematology. His research has been funded by EPSRC, NISCHR, British Council, industrial companies and an RCUK fellowship. He is a Co-Investigator of several EPSRC grants (including the current Healthcare Impact Partnership) with a total value in excess of £5M and is the Principal Investigator of an EPSRC first grant award that is aiding the development of novel haemorheometrical techniques for the measurement of blood coagulation and subsequent breakdown.

Areas of Expertise

  • Rheometry
  • Haemorheology
  • Biopolymer gels

Publications

  1. & Artificial Shear Stress Effects on Leukocytes at a Biomaterial Interface. Artificial Organs
  2. & Characterization of pulp derived nanocellulose hydrogels using AVAP® technology. Carbohydrate Polymers 198, 270-280.
  3. & Control of collagen gel mechanical properties through manipulation of gelation conditions near the sol–gel transition. Soft Matter 14(4), 574-580.
  4. Preface to Special Topic: Papers from the Institute of Non-Newtonian Fluid Mechanics Meeting, Lake Vyrnwy, 2017. Physics of Fluids 29(12), 121401
  5. & The application of large amplitude oscillatory stress in a study of fully formed fibrin clots. Physics of Fluids 29(12), 121606

See more...

Teaching

  • PM-230 Selected Medical Diagnostic Techniques

    This module looks at the design and operation of a wide range of instrumentation used to make measurements for diagnostic and monitoring purposes. The emphasis is on the underlying electrical, mechanical, chemical, optical and other engineering principles.

  • PM-304 Biomolecular Research Project

    *

  • PM-M28 Nano(geno)toxicology

    The field of nanotechnology is ever increasing in size, and the number of nano-sized (1-100nm) particles being produced on a daily basis is at the tonnage level. Although nanotechnology-based applications are considered to be advantageous for a plethora of human activities, the potential risks posed by human exposure to nanoparticles is a constantly developing field of research. The purpose of this module therefore is to introduce to the student to particle toxicology and how it can impact upon human health. Further to this, the students will undertake a specific practical component to complement that of the theoretical content of the module. To this extent, the students will undertake a week-long, 'mini-project', covering the major areas of nanoparticle toxicology. From this approach, it is intended that the student will experience the key points of the field.

  • PMND00 Nanomedicine Research Dissertation

    This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study within nanomedicine.

  • PMNM02 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

  • PMNM07 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

  • PMNMD0 Postgraduate Taught Masters Dissertation

    Students will have the opportunity to join an established research group to work in a modern and well equipped laboratory or alternatively undertake a suitable non-laboratory based project. In this module the student will be able to gain extensive `hands on¿ specialist expertise in a chosen topic which could be targeted to their future career in the field of mass spectrometry. Please note that the topic choice will be made in conjunction with the supervisor, based upon novelty, feasibility and practical considerations on a 'first come first served' basis. The final approval of the topic rests with the module lead.

  • PMZM13 Diagnostics and Imaging

    Nanotechnology may lead to more rapid diagnostic tests, implantable devices, point of care instruments and improved medical imaging. This module will explore the application of nanotechnology to various medical techniques, focussing on novel research devices, pre-clinical tools and emerging technology within hospitals.

Supervision

  • Analysis of the effect of mechanical heart pumps on the blood components (current)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Venkat Kanamarlapudi
  • Analysis of Shear Stress-Induced Von Willebrand Factor and Platelet Damage from Ventricular Assist Devices (current)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Venkat Kanamarlapudi
  • The fabrication of novel polymer scaffolds for regenerative medicine based on collagen derived from jellyfish. (current)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Dr Christopher Wright
  • Development of a Novel Haemo-Rheological Test and Biomarker and its Evaluation in Patients with Stroke (current)

    Student name:
    PhD
    Other supervisor: Prof Adrian Evans
    Other supervisor: Prof Karl Hawkins
  • Rheological Characterisation of Vegetarian Gelling Systems (current)

    Student name:
    PhD
    Other supervisor: Dr Daniel Curtis
    Other supervisor: Prof Karl Hawkins
  • Large amplitude oscillatory stress studies of fibrin gels and blood clots (awarded 2018)

    Student name:
    PhD
    Other supervisor: Prof Adrian Evans
    Other supervisor: Prof Karl Hawkins
  • 'Impact of ventricular assist devices on the activity of white blood cells and the implications for device design and testing.' (awarded 2018)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Prof Catherine Thornton
  • 'Development of advanced ionisation techniques for mass spectrometry' (awarded 2017)

    Student name:
    PhD
    Other supervisor: Prof Karl Hawkins
    Other supervisor: Dr Ruth Godfrey

Administrative Responsibilities

  • Research Theme Lead - Devices

    2016 - Present

  • Programme Director - MSc Nanomedicine

    2014 - Present

  • Member - Medical School Research Committee

    2016 - Present

  • Member - Medical School Learning and Teaching Committee

    2016 - Present

  • Member - Medical School REF Committee

    2015 - Present

  • Member - Medical School Postgraduate Taught Studies Committee

    2014 - Present

Career History

Start Date End Date Position Held Location
2012 Present Associate Professor Swansea University Medical School
2007 2012 RCUK Fellow Swansea University Medical School
2007 Present Research Fellow ABM University Health Board
2007 2007 Visiting Researcher (British Council RXP) Penn Medicine, University of Pennsylvania, USA
2005 2007 Postdoctoral Research Officer Swansea University College of Engineering