1. Godfrey, R. (2017). A ‘Periodic Table’ of mass spectrometry instrumentation and acronyms. Anal. Methods

   https://cronfa.swan.ac.uk/Record/cronfa35170 doi:10.1039/C7AY90114C
2. Godfrey, A., Jones, L., Davies, M. & Townsend, R. (2017). Miltefosine: a novel internal standard approach to lysophospholipid quantitation using LC-MS/MS. Analytical and Bioanalytical Chemistry

   https://cronfa.swan.ac.uk/Record/cronfa31860 doi:10.1007/s00216-017-0223-z
3. Brenton, A. & Godfrey, A. (2014). Electro-Focusing Liquid Extractive Surface Analysis (EF-LESA) Coupled to Mass Spectrometry. Analytical Chemistry 86(7), 3323-3329.

   https://cronfa.swan.ac.uk/Record/cronfa18278 doi:10.1021/ac4035136
4. Townsend, R., Desbrow, C. & Godfrey, R. (2014). Extraction of Over-the-Counter Pharmaceuticals from Water and Sludge Cake Using ISOLUTE® QuEChERS Prior to LC/MS Analysis.. (Application Note, Biotage No. AN831).

   http://www.biotage.com/news/clean-up-of-pharmaceuticals-in-sludge-cake

   https://cronfa.swan.ac.uk/Record/cronfa30932
5. Sargent, M., Sage, A., Wolff , C., Mussell, C., Neville, D., Lord, G., Saeed , M., Lad, R., Hird, S., Barwick, V. & Godfrey, A. (2013). Guide to achieving reliable quantitative LC-MS measurements. LGC.

   https://cronfa.swan.ac.uk/Record/cronfa18279

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• PM-355 Drug Development and Regulation

  This is an applications and project management driven module designed to provide the student with an introduction to drug development and the key role of separation science and mass spectrometry within the pharmaceutical industry. This module will introduce Good Laboratory, Clinical and Manufacturing Practice (GLP, GCP, GMP), assay validation (as requested by the Food and Drug Administration (FDA)), the need and implementation of SOPs with particular focus on the pharmaceutical and medical industries, and how these correlate with stringent quality control procedures and health and safety existing due to current legislation. The ethical principles of research, including clinical trials and animal research (design, implementation and reporting) will be outlined, as well as the essential nature of the principles of reduction, refinement and replacement for the use of animals in research. Students will also be able to characterize and map the path of a drug from administration, to metabolism and elimination, for critical evaluation of drug design.

• PMLM00 Mass Spectrometry - basics and fundamentals

  This module will enable students to gain a sound knowledgebase of the basic concepts of mass spectrometry including the individual components, linking to modern separation techniques, instrument maintenance, spectral interpretation, and the basis of modern applications such as, compound identification by generating a characteristic mass `fingerprint¿ for the chemical structure and compound quantitation.

• PMLM01 Separation science and sample handling

  This module will enable students to understand the basic and advanced concepts of separation science, how it is integrated with several forms of compound detection, gain `hands on¿ problem solving experience and strategic method development for complete bioanalysis according to compound chemical characteristics and method application.

• PMLM03 LC/MS Applications II: Pharmaceutical

  This is an applications driven module designed to provide the student with an extensive knowledgebase of drug development and the role of mass spectrometry within the pharmaceutical industry. Students will be able to characterize and map the path of a drug from administration, to metabolism and elimination, and critically evaluate drug design.

• PMLM04 LC/MS Applications III: Environmental and Forensic Analysis

  This module will provide students with a sound knowledgebase of environmental and forensic analysis by mass spectrometry and several transferable skills suitable for continued professional development. Students will gain an insight into the role mass spectrometry has to play in agriculture and archaeology, in addition to more topical subjects such as monitoring climate change and the fight against crime and terrorism.

• PMLM04A Environmental & forensic analysis

  This module will provide students with a sound knowledgebase of environmental and forensic analysis by mass spectrometry and several transferable skills suitable for continued professional development, including those require within regulated industries. Students will gain an insight into the role mass spectrometry has to play in agriculture and archaeology, in addition to more topical subjects such as monitoring climate change and the fight against crime and terrorism.

• PMLM07 Data analysis and method development

  This module will allow students to statistically evaluate their data acquired using LC-MS to provide meaningful conclusions for their work. This will involve the practical use of `state-of-the-art¿ databases and software analysis tools available to the mass spectrometry community. Students will gain experience using the latest software technology and techniques for their future careers.

• PMLM08 Professional Management and laboratory practice

  This module will cover Good Laboratory, Clinical and Manufacturing Practice (GLP, GCP, GMP) including, experimental design required for assay validation approved by the Food and Drug Administration (FDA). The need and implementation of SOPs with particular focus on the pharmaceutical and medical industries, and how these correlate with stringent quality control procedures and health and safety existing due to current legislation.

• PMLM09 Dissertation: MS experimental project.

  Students will have the opportunity to join an established research group to work in a modern and well equipped laboratory or alternatively undertake a suitable non-laboratory based project. In this module the student will be able to gain extensive `hands on¿ specialist expertise in a chosen topic which could be targeted to their future career in the field of mass spectrometry.

• PMNM11 Nanomedicines, pharmaceuticals and advanced therapeutics

  This module will explore the history and development of molecular medicines and pharmaceuticals, providing the basis for an advanced understanding of next generation therapeutic approaches. Using landmark technology and chemical development phases informed by separation science and mass spectrometry, the module uses an application driven approach to provide the student with an extensive knowledgebase of drug development, the pharmaceutical industry and nanotherapeutics. Students will be able to characterize and map the path of a drug from administration, to metabolism and elimination, and critically evaluate drug design and delivery approaches. Traditional small chemical entities used in molecular medicine will be outlined, using drugs such as taxols and tamoxifen as exemplars. Common target oncology and non-oncology disorders will provide the context; with students encouraged to explore targeted nanoparticle fabrication, drug encapsulation and release profiling, from early first generation drugs such as Abraxane to second generation biologically targeted SMART delivery systems. Future molecular medicines such as antibody drug conjugates and kinase inhibitors will be taught by guest lectures from industry and clinicians, covering the spectrum of drug development to delivery and clinical considerations.

• PMNMD0 Postgraduate Taught Masters Dissertation

  Students will have the opportunity to join an established research group to work in a modern and well equipped laboratory or alternatively undertake a suitable non-laboratory based project. In this module the student will be able to gain extensive `hands on¿ specialist expertise in a chosen topic which could be targeted to their future career in the field of mass spectrometry. Please note that the topic choice will be made in conjunction with the supervisor, based upon novelty, feasibility and practical considerations on a 'first come first served' basis. The final approval of the topic rests with the module lead.

• Untitled (current)

  Student name: Krzysztof Okonski

  MRes

• Untitled (current)

  Student name: Becki Conniff-Jenkins

  MRes

• Application of gas chromatography-mass spectrometry (GC-MS) in the quantitative analysis of organic analytes generated in gasification/pyrolysis coupled Fischer Tropsch (FT) reactor: syngas clean-up and hydrocarbon production. (current)

  Student name: Geraint Sullivan

  PhD

  Other supervisor: Prof Steven Kelly

• Mass spectrometric investigation of pharmaceuticals in environmental matrices: homogenate analysis. (current)

  Student name: Rachel Townsend

  PhD

  Other supervisor: Prof Anthony Brenton

  Other supervisor: Dr Geertje Van Keulen

• 'Development and feasibility of a FLowing Atmospheric Pressure Afterglow (FAPA) Discharge ionisation source' (awarded 2017)

  Student name: Tamara Mcfarlane

  MRes

  Other supervisor: Prof Anthony Brenton

• 'Development of advanced ionisation techniques for mass spectrometry' (awarded 2017)

  Student name: Charlotte Davies

  PhD

  Other supervisor: Dr Karl Hawkins