Areas of Expertise

  • nanoparticles
  • Streptomyces
  • molecular biology
  • insect symbionts
  • genomics

Publications

  1. Del Sol , R., Jones, H., Dyson, P., Del Sol Abascal, R., Hitchings, M., Facey, P. A tale of tails: deciphering the contribution of terminal tails to the biochemical properties of two Dps proteins from Streptomyces coelicolor. Cell Mol Life Sci
  2. Del Sol Abascal, R., Dyson, P., Walker (neeWhitten), M., Hitchings, M., Facey, P., Meric, G. Draft genomes, phylogenetic reconstruction and comparative genomics of two novel cohabiting bacterial symbionts isolated from Frankliniella occidentalis. Genome Biology and Evolution
  3. Mejia, A., Millan-Pacheco, C., Barrios-Gonzalez, J., Sol, R., Dyson, P., Godinez, O., Del Sol Abascal, R. Targeting the Osmotic Stress Response for Strain Improvement of an Industrial Producer of Secondary Metabolites Journal of Microbiology and Biotechnology 25 11 1787 1795
  4. Del Sol Abascal, E., Del Sol Abascal, R. A DNA fragment from Streptomyces peucetius activates biosynthesis of actinorhodin in Streptomyces lividans and daunomycin in the original strain Biotechnology Letters 23 4 289 293
  5. Del Sol Abascal, E., Del Sol Abascal, R. A DNA fragment from Mycobacterium bovis (BCG) activates secondary metabolism in Sterptomyces Biotechnology Letters 17 4 351 354

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Teaching

  • PM-120 Skills for Geneticists I

    This module is designed to develop the skills required for students of genetics and medical genetics. Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.

  • PM-200 Skills For Geneticists II

    This module will give assignments designed to build on essay writing and oral presentation skills introduced in level 1. It will also develop critical evaluation, analysis skills for the understanding of peer-reviewed research papers.

  • PM-251 Microbial Molecular Genetics

    The control systems governing gene expression in prokaryotic cells are explored and the molecular basis for gene regulation introduced. Practical skills in obtaining and analysing data on a bacterial system are developed. The module then assesses the structure of the bacterial genome and how genetic analysis can be used to investigate structure and function of individual components of that genome. Specific examples explored in depth are the genetics of recombination and DNA repair. The technologies used for functional genomic analysis of fully sequenced bacteria are described with reference to analysis of human pathogens. Finally, the module includes examples of synthetic biology applied to bacteria.

  • PM-253 Techniques in Molecular Biology

    The module will provide a sound theoretical and practical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, transcriptomics, proteomics and mass spectrometry.

  • PM-253C Technegau Bioleg Foleciwlaidd

    Bydd y modiwl yn darparu sylfaen ddamcaniaethol ac ymarferol gref ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, transgriptomeg, proteomeg a sbectrometreg màs.

  • PM-304 Biomolecular Research Project

    *

  • PM-315 Skills For Geneticists III

    The module aims to develop the student¿s ability to critically analyse and synthesise advanced research topics in genetics and molecular biology, and their oral and written scientific presentation skills.

  • PM-315C Sgiliau ar gyfer Genetegwyr III

    Amcan y modiwl yw datblygu gallu'r myfyriwr i ddadansoddi'n feirniadol a syntheseiddio pynciau ymchwil uwch ym maes geneteg a bioleg foleciwlaidd, ac i feithrin eu sgiliau cyflwyno gwyddonol llafar ac ysgrifenedig.

  • PM-345 Bioinformatics: From sequence to Function

    The ever increasing availability of genome sequences and protein structure data demands that molecular biologists are proficient at performing extensive data analyses to guide and support traditional laboratory-based research. This Module will provide the theoretical basis and practical training on computational tools currently used to assemble and interrogate genome sequences, infer gene and protein functions, and to examine protein structure data.

  • PM-357 Biomedical Laboratory Techniques

    The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.

  • PM-357C Technegau Labordy Biofeddygol

    Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.

  • PM-402 Advanced Research Project B

    The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an 9-month period. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-402 comprises the final written dissertation.

Supervision

  • Monitoring inflammatory response to pre-infectious pathogens. (current)

    Student name:
    MSc
    Other supervisor: Prof Steve Conlan
  • Genomic interrogation of Candida albicans with relation to reproductive health and fertility (current)

    Student name:
    MSc
    Other supervisor: Dr Paul Facey
  • Genome guided evaluation of probiotic bacteria from the Lactobacillus and Bifidobacterium genera. (current)

    Student name:
    PhD
    Other supervisor: Dr Paul Facey
  • Characterising novel Antibody-Drug Conjugate targets for ovarian cancer: Implications for patient stratification and precision medicine (current)

    Student name:
    PhD
    Other supervisor: Prof Steve Conlan
  • A Genome Sequence view of the Microbiome in Two Insect Species: Relevance to the Prey and Predator Relationship (current)

    Student name:
    PhD
    Other supervisor: Prof Paul Dyson
  • Microbiome Characterization Guides the Development of Novel Pest Control Strategies: Lessons Derived From F. occidentalis Microbial Symbionts (current)

    Student name:
    PhD
    Other supervisor: Prof Paul Dyson
  • Untitled (current)

    Student name:
    MSc
    Other supervisor: Dr Paul Facey
  • 'Study of the correlation between archived metal polluted soils and microbial resistance to antibiotics and metals' (awarded 2018)

    Student name:
    PhD
    Other supervisor: Dr Geertje Van Keulen
  • 'Population genomics approaches to understanding the evolution and ecology of bacterial pathogens' (awarded 2018)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson
  • 'Population genomics of bacterial pathogens' (awarded 2018)

    Student name:
    PhD
    Other supervisor: Dr Thomas Wilkinson