Areas of Expertise
- molecular biology
- insect symbionts
This module is designed to develop the skills required for students of genetics and medical genetics. Students will meet with tutors and be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy. Joint sessions will cover generic skills such as internet searching for scientific sources, referencing and plagiarism.
This module will give assignments designed to build on essay writing and oral presentation skills introduced in level 1. It will also develop critical evaluation, analysis skills for the understanding of peer-reviewed research papers.
The control systems governing gene expression in prokaryotic cells are explored and the molecular basis for gene regulation introduced. Practical skills in obtaining and analysing data on a bacterial system are developed. The module then assesses the structure of the bacterial genome and how genetic analysis can be used to investigate structure and function of individual components of that genome. Specific examples explored in depth are the genetics of recombination and DNA repair. The technologies used for functional genomic analysis of fully sequenced bacteria are described with reference to analysis of human pathogens. Finally, the module includes examples of synthetic biology applied to bacteria.
The module will provide a sound theoretical and practical basis to a comprehensive range of biomolecular techniques currently employed in molecular genetics and biochemistry. Particular emphasis is placed on DNA recombinant technology, next generation sequencing, transcriptomics, proteomics and mass spectrometry.
Bydd y modiwl yn darparu sylfaen ddamcaniaethol ac ymarferol gref ar gyfer ystod gynhwysfawr o dechnegau biofoleciwlaidd a ddefnyddir ar hyn o bryd mewn geneteg foleciwlaidd a biocemeg. Rhoir pwyslais penodol ar dechnoleg ailgyfuno DNA, dilyniannu cenhedlaeth nesaf, transgriptomeg, proteomeg a sbectrometreg màs.
The module aims to develop the student¿s ability to critically analyse and synthesise advanced research topics in genetics and molecular biology, and their oral and written scientific presentation skills.
Amcan y modiwl yw datblygu gallu'r myfyriwr i ddadansoddi'n feirniadol a syntheseiddio pynciau ymchwil uwch ym maes geneteg a bioleg foleciwlaidd, ac i feithrin eu sgiliau cyflwyno gwyddonol llafar ac ysgrifenedig.
The ever increasing availability of genome sequences and protein structure data demands that molecular biologists are proficient at performing extensive data analyses to guide and support traditional laboratory-based research. This Module will provide the theoretical basis and practical training on computational tools currently used to assemble and interrogate genome sequences, infer gene and protein functions, and to examine protein structure data.
The module will provide practical and in depth theory of applications and equipment available to MSci students in the biomedical research laboratories based at the Medical School. The module will provide guidelines and rationale for experimental design, and data and statistical analysis.
Bydd y modiwl yn darparu damcaniaeth ymarferol a manwl o¿r cymwysiadau ac offer sydd ar gael i fyfyrwyr MSci yn y labordai ymchwil biofeddygol sydd wedi'u lleoli yn yr Ysgol Feddygaeth. Bydd y modiwl yn darparu canllawiau a rhesymeg ar gyfer cynlluniau arbrofol, a dadansoddiad data ac ystadegau.
The advanced research project is a key component of the final year of study, providing students with experience of conducting cutting-edge research in the Institute of Life Science and Centre for Nanohealth over an 9-month period. The project will fall into one of the current medically-related research themes: Biomarkers and Genes; Microbes and Immunity; Devices. Students will employ a range of advanced analytical procedures to investigate a specific topic. In addition, they will gain experience in preparing a research proposal and presenting their data in various formats. Research topics will be assigned that are appropriate to a specific degree title. For example, a Genetics student could be assigned a project investigating gene function in an insect vector of a tropical disease, using the technique of RNA interference. The advanced research project is divided between 2 modules, PM-400 and PM-402. PM-402 comprises the final written dissertation.