I studied both my BSc and MSc in Biomedical Science in University of Wales Institute, Cardiff, specialising in Forensic Toxicology and Medical Microbiology. Following this I was fortunate enough to be awarded a NISCHR Welsh Office of Research and Development PhD (2009), investigating the role of exercise in preventing the progression of Type 2 diabetes and associated cardiovascular effects e.g. atherosclerosis and cell polarisation effects. This allowed me the opportunity to carry out in vivo projects and develop a keen interest in the effects of inflammation on cell signalling pathways and their role in disease progression.

My time as a post-Doctoral researcher was spent in the Haemostasis Biomedical Research Unit, investigating the role of inflammation in haemostasis and how this varies in hypo- and hyper-coagulable states. Based in an Emergency Department in Morriston Hospital, I developed a keen interest in Emergency Medicine Research and was involved in a number of studies investigating the role of haemostasis in stroke, cardiac, sepsis and burns patients. I successfully led and completed a project investigating the changes in haemostasis in patients with lung cancer, quantifying changes to clot structure using a cutting edge haemorheological technique, developed here in Swansea University between Medical School and the College of Engineering.

Currently I am director of the Foundation Year for the BSc Applied Medical Sciences degree programme, aiming to widen access to Higher Education. In addition I am a lecturer and disability link tutor on the BSc Applied Medical Sciences, co-ordinating and contributing to several modules including laboratory skills, anatomy, physiology and pathophysiology.  

Publications

  1. & An Investigation Into the Effects of In Vitro Dilution With Different Colloid Resuscitation Fluids on Clot Microstructure Formation. Anesthesia & Analgesia 123(5), 1081-1088.
  2. Fractal dimension (df) as a new structural biomarker of clot microstructure in different stages of lung cancer. Thrombosis and Haemostasis 114(6), 1251-1259.
  3. Application of ROTEM to assess hypercoagulability in patients with lung cancer. Thrombosis Research 135(6), 1075-1080.
  4. & PO-25 - FATCAT: an observational cohort study investigating fractal dimension (df) as a biomarker of thrombogenicity in cancer associated thrombosis during chemotherapy for lung cancer. Thrombosis Research 140, S185
  5. & Effects of exercise intensity on clot microstructure and mechanical properties in healthy individuals. Thrombosis Research 143, 130-136.

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Teaching

  • PM-002 The Human Cell

    This module will provide the learner with a broad overview of the human body, from cell structure and organisation to organs and organ systems. The module will focus on blood; in particular how it functions in the circulatory system and infection. Cancer cell proliferation will be introduced in this module via haematological malignancies. This module will be supported by 2 practical sessions and essay with academic support.

  • PM-138C Sgiliau ar gyfer Gwyddorau Meddygol

    Nod y modiwl hwn yw darparu¿r sgiliau sylfaenol sydd eu hangen ar fyfyrwyr ar gyfer ymchwil labordy ym maes y gwyddorau meddygol cymhwysol. Bydd y modiwl yn cynnwys gwaith damcaniaethol a chymhwysol: caiff y myfyriwr ei hyfforddi mewn dulliau sy¿n hanfodol ar gyfer caffael data a¿i ddadansoddi, ond bydd hefyd yn cymryd rhan weithredol yn y labordy, gan ddefnyddio¿n fras y technegau arbrofol perthnasol. Byddant hefyd yn datblygu sgiliau nad ydynt yn dechnegau arbrofol yn eu hunain, ond sydd er hynny, yn sylfaenol i¿r broses wyddonol, megis, mathemateg y labordy¿, cyrchu gwybodaeth, cyfeirnodi, moeseg ac iechyd a diogelwch.

  • PM-259 Contemporary themes and techniques in medical sciences

    This module aims to give students an overview of current and emerging themes in medical sciences, both from clinical and laboratory perspectives. This will cover topics generating high media interest, such as the zika virus and alternative methods of transplantation as well as new laboratory techniques. In addition, the module will be supported by two practical classes for which students will be required to conduct mini-projects based around the identification of patient samples and how these are presented as research cases. The module will also involve a one-day "conference", during which students will present data while experiencing a research conference atmosphere.

  • PM-353 From Bench to Beside: an Introduction to Clinical Trials

    Clinical trials are conducted to determine whether medical interventions, like treatment strategies or devices, are safe and effective in humans. This is an expanding and highly competitive field of research, yet employers find it challenging to recruit people with the appropriate skills and knowledge. Taught by leading researchers currently involved in these studies, in this module, you will gain an introduction to trial research methodology. Using real, published studies, you will be introduced to study design, conduct, analysis and critical appraisal. You will learn about early to late phase trials as well as simple versus complex design. You will also learn to recognise whether certain treatments are more or less effective in particular groups of people and learn about the responsible reporting of study outcomes