Sgiliau ar gyfer Gwyddorau Meddygol
Nod y modiwl hwn yw darparu¿r sgiliau sylfaenol sydd eu hangen ar fyfyrwyr ar gyfer ymchwil labordy ym maes y gwyddorau meddygol cymhwysol. Bydd y modiwl yn cynnwys gwaith damcaniaethol a chymhwysol: caiff y myfyriwr ei hyfforddi mewn dulliau sy¿n hanfodol ar gyfer caffael data a¿i ddadansoddi, ond bydd hefyd yn cymryd rhan weithredol yn y labordy, gan ddefnyddio¿n fras y technegau arbrofol perthnasol. Byddant hefyd yn datblygu sgiliau nad ydynt yn dechnegau arbrofol yn eu hunain, ond sydd er hynny, yn sylfaenol i¿r broses wyddonol, megis, 'mathemateg y labordy¿, cyrchu gwybodaeth, cyfeirnodi, moeseg ac iechyd a diogelwch.
Human Physiology II
This module aims to provide students with further understanding of human physiology through studies on systems physiology including the endocrine, renal, blood, digestive/metabolism and reproductive system. The module will equally describe how malfunction of physiological systems gives rise to disease, using specific examples to enable students to appreciate the relationship between physiology/anatomy and medicine. Fundamental principles of physiology will be illustrated with appropriate clinical examples and during practical assignments.
Introduction to Toxicology: The Dose Makes the Poison
We are surrounded by substances that may do our bodies harm i.e. poisons. The harm these poisons causes depends on our exposure - the dose. The science of toxicology, a discipline that crosscuts biology, chemistry, pharmacology, and
medicine, is based on the principle that the dose makes the poison.
This module will provide you with an introduction to toxicology and how dose-response relationships relate to the physiological effects of toxic substances. You will explore how they produce cellular and chemical changes that cause tissues and organs to malfunction.
You will learn how the structure and function of these tissues can be affected to varying degrees and begin to understand how tissue may repair itself and when the damage is reversible, permanent or fatal.
You will also learn how we use toxic substances to our advantage in both the laboratory and within the clinic.
Human physiology is the study of how our body works in an integrated way. A central principle of human physiology is homeostasis, the maintenance of a relatively stable internal environment. Failure to maintain homeostasis disrupts normal function that may lead to disease (or pathophysiology). Students will be taught the key concepts of homeostasis in the physiological systems of the body, enabling the student to understand the consequences of pathophysiology to human health.
Emphasis will be given to how malfunction of key physiological systems gives rise to disease, using specific examples to enable students to appreciate the relationship between physiology/anatomy and medicine. Fundamental principles of physiology will be illustrated with appropriate clinical examples and during lectures and in practical assignments.
Students will gain practical experience in assessing physiological function during four laboratory-based exercises. The impact of pathophysiology of such systems will be assessed through clinical case studies.
Introduction to Pharmacology: Dynamics and Kinetics
The aim of this module is to introduce students to basic principles of pharmacology, focussing on how drugs work on the human body (pharmacodynamics) and how the body works on drugs (pharmacokinetics). These discussions will be placed in the context of pharmacology as a discipline today and the emergence of biotechnology, including the sub-disciplines of pharmacogenomics, pharmacoepidemiology, and pharmacoeconomics. Alternative therapeutic principles will also be critiqued according to the scientific evidence base.
Advances in Toxicology: Pick Your Poison
We are surrounded by substances that may do our bodies harm i.e. poisons. The harm these poisons causes depends on our exposure - the dose. The science of toxicology, a discipline that crosscuts biology, chemistry, pharmacology, and medicine, is based on the principle that the dose makes the poison.
This module is compulsory for BSc Medical Pharmacology students and acts as a follow on from PM-147 Introduction to Toxicology: The Dose Makes the Poison.
This module will provide students with the opportunity to expand their toxicology knowledge and apply it to three distinct fields within toxicology; analytical toxicology, forensic toxicology and clinical toxicology.
Students will learn about the experimental procedures and techniques we employ for the isolation and detection of compounds as well as their effects on biological systems. Students will then learn about the role of employing these methods in the field of forensic toxicology and the role of toxicology within the legal system.
Within the module, students will also learn about the role of clinical toxicology and patient presentation following poisoning events and the techniques we have for detection and treatment of toxicology within the clinical setting.
Being a Medical Scientist
Much of a scientist¿s career is spent writing and speaking about science. The aim of this module is to give students a higher level experience of what being a lead researcher is like, away from the lab bench. Drawing on core knowledge from other modules, students will refine their oral and written communication and learn what leadership skills are needed to succeed in modern science. They will also be challenged to consider ethical aspects of research, including new technologies and the use of animal and human subjects. The module will be highly interactive, taught using informal lectures interspersed with students working in groups. Assessments will include an ethics application, a group Journal Club presentation on a published, peer-reviewed research article, and a mock grant proposal.
Advances in Pharmacology
Pharmacology is the science of how drugs act on the body and how the body acts on drugs.
Pharmacology investigates the chemical and physical properties of drugs, how those properties confer actions on living tissues and how those actions affect health and disease. In this module, students will build upon their previous pharmacology knowledge and look more in depth at how the body interacts with drugs (pharmacokinetics) and how the drug interacts with the body (pharmacodynamics).
In this module, students will study the drugs and therapeutics currently used in clinical practise and the underlying mechanisms of action of these drugs. Students will learn about the beneficial, therapeutic effects of drugs, but also some negative consequences of drug administration, such as toxicity, addiction and microbial drug-resistance. Additionally, students will learn about the cutting-edge therapies currently in development for treating disease.
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own
enquiry-based research project. The project may be laboratory or non-laboratory based, but it will always involve a
research question that is drawn from the literature, and focused on a topic relevant to medical science. It will ask a
novel research question and involve the critical analysis of research findings. Students will refine their oral and
written communication skills to a graduate level through creating an introductory presentation on the project
background, and a written dissertation and oral presentation on their research conclusions.
The Neuroscience of Learning, Memory and Cognition
How do we perceive and make sense of the world?
How do we learn?
Why do we learn?
What happens when these things go wrong?
Learning, memory and cognition will be explored from a neuroscience perspective. We will consider the functional anatomy of the brain, and medical situations which affect learning, memory and cognition.